CAS: 34255-08-8; Spirilloxanthin

📜(3'E)-1,1'-Dimethoxy-3',4'-Didehydro-1,2,1',2'-Tetrahydro-ψ,ψ-Caroten-4-One置于盐酸,钾硼氢,氯仿体系中,用 乙醇 用作溶剂,化学反应 0.07H,反应生成(4E,6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E,28E)-2,31-二甲氧基-2,6,10,14,19,23,27,31-八甲基三十二碳-4,6,8,10,12,14,16,18,20,22,24,26,28-十三烯
参考文献:Schmidt; Liaaen-Jensen,Acta Chemica Scandinavica (1947),1973,Vol. 27,# 8,P. 3040-3052
标题:Schmidt; Liaaen-Jensen,Acta Chemica Scandinavica (1947),1973,Vol. 27,# 8,P. 3040-3052

专利信息

专利号:US-7741070-B2
优先权日:2003-12-24
标 题 :Gene targets for enhanced carotenoid production
发明人：STEPHANOPOULOS GREGORY; ALPER HAL S; JIN YONG-SU
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides engineered cells and methods for utilizing same. Methods of enhanced carotenoid synthesis utilizing cells genetically disrupted for a yjiD, hnr or yjfP gene, or further disrupted for a gdhA, gpmB, aceE, ppc, talB or fdhF gene, or any combination thereof, or cells inhibited for their expression, activity or function are disclosed. Additionally, methods of enhanced carotenoid synthesis utilizing cells genetically disrupted for gdhA, aceE, fdhF, yjiD, hnr or yjfP gene expression or any combination thereof and ackA, appY, aspC, clp, clpP, clpXP, crcB, csdA, cyaA, evgS, fdhA, fdhD, feoB, funA, glnE, glxR, gntK, hycI, lipB, lysU, modA, moeA, nadA, nuoC, nuoK, pflB, pitA, pst, pstC, pta, p-yjiD, sohA, stpA, yagR, yaiD, ybaS, ycfZ, ydeN, yebB, yedN, yfcC, ygjP, yibD, yjfP, yjhH, or yliE gene expression, or a combination thereof or cells inhibited for their expression, activity or function are disclosed. Methods of enhanced carotenoid synthesis utilizing cells genetically engineered to overexpress dxs, idi, ispFD, yjiD, rpoS, torC, appY, ydgK, yeiA, yedR, tort, arcB, yggT, purDH, yfjN or a combination thereof, or further disrupted for the above-referenced genes are disclosed. Methods for identifying genes involved in optimized production of a carotenoid, and cells disrupted for, or inhibited for the expression, activity or function of genes thus identified are described.

专利号:US-7695932-B2
优先权日:2003-12-24
标 题:Gene targets for enhanced carotenoid production
发明人：STEPHANOPOULOS GREGORY; ALPER HAL S; JIN YONG-SU
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present invention provides genetically manipulated cells and methods for utilizing same. Methods of enhanced carotenoid synthesis utilizing cells genetically disrupted for a yjiD, hnr or yjfP gene, or further disrupted for a gdhA, gpmB aceE, ppc, talB or fdhF gene, or any combination thereof, or cells inhibited for their expression, activity or function are disclosed. Methods of enhanced carotenoid synthesis utilizing cells genetically engineered to overexpress dxs, idi, yjiD, rpoS, torC, appY, ydgK, yeiA, yedR, tort, arcB, yggT, purDH, yfjN or a combination thereof, or further disrupted for the above-referenced genes are disclosed. Methods for identifying genes involved in optimized production of a carotenoid, and cells disrupted for, or inhibited for the expression, activity or function of genes thus identified are described.

专利号:US-7504236-B2
优先权日:2005-09-15
标题 :Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
发明人：MILLER JR EDWARD S; ODOM JAMES M; SHARPE PAMELA L
权利人:DU PONT
摘要:A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a carotenogenic microbial host cell significantly increased carotenoid production. Carotenogenic microorganisms are also provided that have been optimized for the production of carotenoid compounds through the down-regulation and/or disruption of glycogen synthase activity.