CAS: 22118-12-3; 2-Bromobutyrylchloride

该化合物是有机合成中,特别是在生产药品,农用化学品和特殊化学品时使用的多种通气剂,其反应性溴和丙基氯功能使得能够有效地将二溴丁基内分泌引入目标分子,促进进一步转化,如核生殖替代或混合反应.该化合物的高度反应性和选择性使得它对于建造复杂的分子结构具有价值.由于对水分的敏感性,它通常在缺水条件下处理.适当的储存和处理对于维持稳定性和防止分解至关重要.应用包括将其用作活性药物成分和精细化学物合成的中间体.

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7148-74-5 18791-02-1 4509-90-4

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CAS号80-58-0 2-溴丁酸 | CAS号141-75-3 丁酰氯 | CAS号107-92-6 正丁酸 | CAS号3196-15-4 2-溴丁酸甲酯 | CAS号1440-82-0 (2,6-dimethoxyp... | CAS号20334-52-5 C2H5CH=C=O | CAS号36717-59-6 5-ethyloxolane-... | CAS号881-43-6 2-bromo-1-(4-me... | CAS号42115-51-5 benzyl 2-bromob... | CAS号5398-24-3 2-溴丁酰胺 | CAS号54261-07-3 1-(2-Bromobutan...

合成工艺路线路线简述

    丁酸 反应生成2-溴丁酰氯
    参考文献:Efficient .Alpha.-Halogenation Of Acyl Chlorides By N-Bromosuccinimide,N-Chlorosuccinimide,And Molecular Iodine
    标题:Efficient .Alpha.-Halogenation Of Acyl Chlorides By N-Bromosuccinimide,N-Chlorosuccinimide,And Molecular Iodine
    摘要:
    Doi:10.1021/jo00911A026

    海关参考信息

    专利信息


    专利号:US-2023117284-A1
    优先权日:2020-02-11
    标题 :Process for the synthesis of s-beflubutamid from (r)-2-aminobutanoic acid
    发明人:DATAR RAVINDRA V; MAO JIANHUA
    权利人:CHEMINOVA AS
    摘要:Disclosed are methods for preparing compound S-1 (S-1) from (R)-2-bromobutanoic acid prepared by treating (R)-2-aminobutanoic acid with an alkali metal nitrite compound and hydrobromic acid.

    专利号:CN-112195203-B
    优先权日:2020-11-10
    标题 :A kind of method for enzymatic synthesis of (S)-2-aminobutanamide

    专利号:CN-109678752-A
    优先权日:2018-12-27
    标 题:A kind of method for asymmetric transformation and synthesis of L-2-aminobutanamide hydrochloride

    专利号:EP-0946526-B1
    优先权日:1996-12-04
    标 题 :Macrocyclic metal complex carboxylic acids, use and method for the production thereof
    发明人:PLATZEK JOHANNES; SCHMITT-WILLICH HERIBERT; RADUECHEL BERND
    权利人:SCHERING AG
    摘要:The invention relates to novel macrocyclic metal complex carboxylic acids of formula (II), wherein Z DEG means a metal iron equivalent of atomic numbers 58-71 and R is a CHX<1>-CO-NH-CHY<1>-(CH2)f-COOH group, wherein X<1> and Y<1> mean individually a hydrogen atom, a straight-chained or branched C1-C7-alkyl radical, a phenyl or benzyl group and f means the figures 0-9. Said acids can be used as intermediate preparations for synthesis of cascade polymer complexes suitable as diagnostic agents.

    专利号:US-5919433-A
    优先权日:1996-12-04
    标 题:Macrocyclic metal complex carboxylic acids, their use as well as process for their production
    发明人:PLATZEK JOHANNES; RADUECHEL BERND; SCHMITT-WILLICH HERIBERT
    权利人:SCHERING AG
    摘要:The invention relates to new macrocyclic metal complex carboxylic acids of formula II whereby Zo stands for a metal ion equivalent of atomic numbers 58-71 and R stands for a CHX1-CO-NH-CHY1-(CH2)f-COOH group, in which X1 and Y1, independently of one another, mean a hydrogen atom, a straight-chain or branched C1-C7 alkyl radical, a phenyl or benzyl group and f means numbers 0 to 9. They can be used as intermediate stages for synthesis of cascade polymer complexes that are suitable as diagnostic agents.

    专利号:CN-112195203-A
    优先权日:2020-11-10
    标题 :A kind of method for enzymatic synthesis of (S)-2-aminobutanamide
    铜陵立事达化学科技有限公司
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    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
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