CAS: 1984-27-6; 4-Bromo-N-Isopropylbenzenesulfonamide
该化合物是一种有机化合物,其特点是存在一个溴原子,一个磺酰胺功能组,以及苯环上的异丙基替代物.该化合物一般在室温时是一种固体,在极地有机溶剂中可溶解.由于磺酰胺具有抗菌性能,因此它具有作为制药中间体的潜力.溴基二苯二酰二甲胺的替代物可以增强该化合物的再活性,使其在各种化学反应中有用,包括电光学芳香替代.此外,异丙基磺可影响该化合物的消毒性能和电子特性,影响其在生物系统中的相互作用.安全数据表明,与许多溴化化合物一样,应对该化合物的处理应顾及潜在的毒性和环境关切.
- 英文名称4-Bromo-N-Isopropylbenzenesulfonamide
- 中文名称4-溴-N-异丙基苯磺酰胺
- IUPAC名称4-bromo-N-isopropylbenzenesulfonamide
- 其它别名4-Bromo-N-Isopropylbenzenesulphonamide; P-Bromo-N-Isopropyl-Benzenesulfonamid; N-Isopropyl 4-Bromobenzenesulfonamide; 4-Bromo-N-Isopropylbenzenesulphonamide ; 4-Bromo-N-Isopropylbenzenesulphonamide; N-Isopropyl-P-Bromobenzenesulfonamide; 4-Bromo-N-Isopropyl-Benzenesulfonamide; 4-Bromo-N-Propan-2-Ylbenzenesulfonamide
- CAS编号1984-27-6
- MFCD编号:MFCD01215090
- EINECS号:640-894-5
- 分子式:C9H12BrNO2S分子量:278.17
- 产品CID: 1009706
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
CAS号108-20-3 异丙醚 | CAS号701-34-8 4-溴苯磺酰胺 | CAS号75-31-0 异丙胺 | CAS号98-58-8 对溴苯磺酰氯 | CAS号701-34-8 4-溴苯磺酰胺合成工艺路线路线简述
📜异丙醚,4-溴苯磺酰胺置于三氟甲磺酸体系中,用 甲苯 用作溶剂,化学反应 45.0H,以70%的收率获得n-异丙基-4-溴苯磺酰胺
参考文献:Brønsted Acid-Assisted N-Alkylation Of Sulfonamides Using Ethers As The Alkylation Reagents
标题:Brønsted Acid-Assisted N-Alkylation Of Sulfonamides Using Ethers As The Alkylation Reagents
摘要:N-Alkylation Of Sulfonamides Using Cyclic Ethers As Alkylation Reagents And Bronsted Acid As A Catalyst Produced Pyrrolidine And Piperidine Derivatives In Good Yields. When Using Symmetrical And Unsymmetrical Ethers As Alkylation Reagents,Mono-N-Allcylation Of Sulfonamides Took Place To Afford The Corresponding Products. (C) 2013 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tet.2013.11.036
专利信息
专利号:US-5783699-A
优先权日:1986-10-22
标 题:Chemiluminescent acridinium salts
发明人：MATTINGLY PHILLIP GREGORY; BENNETT LARRY GENE
权利人:ABBOTT LAB
摘要:Acridinium sulfonylamides and isomers, such as phenanthridinium sulfonylamides, may be employed in applications including chemiluminmescent immunoassays. Methods for synthesis of these compounds include contacting an amine with a sulfonylhalide to form a sulfonamide and acylating with an activated carboxylic acid of an acridine or isomer thereof. The N-sulfonyl-9-acridinium carboxamide and isomers may be conjugated to antigens, haptens, antibodies, and nucleic acids for use in chemiluminescent assays.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Journal of Medicinal Chemistry., 8(548), 1965
📝 需求与反馈
尽可能描述清楚需求与问题信息
