CAS: 17475-41-1; 3-Ethylisobenzofuran-1(3H)-One

该化合物是有机化合物,其特点是双环结构,其中包括一个被熔化的超正辛诺美酒,该化合物通常呈现黄色色色,褐色光色,由于存在苯环而闻名于其芳香性.碳骨的乙基组因存在苯乙烯环而导致其疏水性,影响其在有机溶剂中的溶解性,同时使其在水中不易溶解.该产品可能具有各种功能特性,包括药物,农用化学品合成中的潜在应用,或因其独特的结构特征而用作调味剂.该化合物的再活性可归因于碳基组的存在,该组可能参与各种化学反应,例如核嗜好性添加物或环球变.此外,其在不同条件下的稳定性和行为可能受温度和pH等因素的影响.总体而言,1,3H(H)-西优美诺酮,3乙基是有机化学及相关领域的利益复合物.

结构式图片

相似化合物

6066-49-5 72424-08-9 199736-94-2

欧盟法规

C&L通报

上下游产品

diazomethanediazomethane diazomethanediazomethane diethylzinc 2-(prop-1-en-1-yl)benzoic acid 2-(n-Propyl)-benzoesaeure 1-(1-hydroxypropyl)-2-hydroxymethylbenzene

合成工艺路线路线简述

    📜N,N-二乙基苯甲酰胺置于吡啶,Sodium Tetrahydroborate,四甲基乙二胺,仲丁基锂,Sodium Hydride,对甲苯磺酸,臭氧,鹰爪豆碱体系中,用 四氢呋喃,甲醇,二甲基亚砜,甲苯,正戊烷 用作溶剂,化学反应 3.0H,反应生成丁苯酞杂质
    参考文献:Enantioselective [2,3]-Wittig Rearrangement Via Sparteine-Mediated Lateral Metalation Of N,N-Dialkyl-O-Allyloxymethylbenzamides And O-Substituted Benzyl Prenyl Ethers
    标题:Enantioselective [2,3]-Wittig Rearrangement Via Sparteine-Mediated Lateral Metalation Of N,N-Dialkyl-O-Allyloxymethylbenzamides And O-Substituted Benzyl Prenyl Ethers
    摘要:已研究了(-)-Sparteine介导的n,N-二烷基-O-烯丙氧基甲基苯酰胺和o-取代苄基普尼醚的对映选择性[2,3]-Wittig重排.使用n,N-二乙基-O-烯丙氧基甲基苯酰胺时,在戊烷中观测到了高达60%的对映体过量.这些结果表明,氨基羧基可以通过与(-)-Sparteine-N-Buli复合物的配位有效地辅助立体信息的传递.其他功能团(ome,oconr2,Omom,F)对该重排的对映体分化无效.
    Doi:10.1055/s-1998-1978

    海关参考信息

    专利信息


    专利号:US-7692019-B2
    优先权日:2000-12-04
    标 题:Methods for the stereoselective synthesis of substituted piperidines
    发明人:AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HEFFERNAN MICHELE L R; HOEMANN MICHAEL Z; KESSLER DONALD W; SHAO LIMING; WU XINHE; XIE ROGER L
    权利人:SEPRACOR INC
    摘要:One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.

    专利号:US-2015045564-A1
    优先权日:2012-01-03
    标 题 :Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES
    发明人:REDDY SANTHOSH REKULA; PRAGATI KISHORE PRASAD; NAGA KIRAN; SUDALAI ARUMUGAM
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention disclosed herein is a novel commercially feasible, one pot synthesis of library of 3-substituted phthalides of formula I via CuCN mediated oxidative cyclization in high yield. Formula I

    专利号:WO-2013102935-A2
    优先权日:2012-01-03
    标 题:Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 159.
    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 184.
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