CAS: 1637-73-6; Sodium 1-Hydroxypropane-1,2,3-Tricarboxylate

相似化合物

6132-04-3 676-46-0 18996-35-5

专利信息

专利号:US-2025250599-A1
优先权日:2024-02-05
标 题:POLYPHOSPHATE KINASES (PPKs) FOR EFFICIENT REGENERATION OF GUANOSINE TRIPHOSPHATE (GTP) AND USE THEREOF
发明人：LIU LUO; Cao Chenqi; WU LINBO; WANG RUIKAI; LIU CHENYUAN; JIANG LINTONG
权利人:UNIV BEIJING CHEM TECH
摘要:Polyphosphate kinases (PPKs) for efficient regeneration of guanosine triphosphate (GTP) and use thereof are provided, belonging to the field of biotechnology. The PPKs expressed and obtained in Escherichia coli BL21(DE3) can efficiently regenerate the GTP using tripolyphosphate (tripolyP), tetrapolyP, and hexametaphosphate as phosphate donors. Use of the PPKs in regeneration of GTP as well as synthesis of guanosine diphosphate (GDP)-L-fucose or GDP-mannose and a derivative thereof (such as fucosyllactose) significantly improves synthesis sustainability and reduces a synthesis cost.

专利号:US-6255475-B1
优先权日:1995-01-31
标 题:Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation
发明人：KWIATKOWSKI MAREK
摘要:The invention relates to compounds of general structure (I) or salts thereof, wherein B is a nucleobase, X and Z independently are oxygen or sulphur, Y is hydrogen or hydroxy, which optionally may be protected, R 1 is hydrocarbyl, which optionally is substituted with a functional group, R 2 is hydrogen or hydrocarbyl, which optionally is substituted with a functional group, A is an electron withdrawing or electron donating group capable of moderating the acetal stability of compound (I), L 1 and L 2 are hydrocarbon linkers, which may be the same or different, L 2 , when present, being either (i) connected to L 1 via the group A, or (ii) directly connected to L 1 , the group A then being connected to one of linkers L 1 and L 2 , F is a dye label, Q is a coupling group for F, and l, m and n independently are 0 or 1, with the proviso that l is 1 when m is 1, and l is 1 and m is 1 when n is 1. The compounds of formula (I) are useful as deactivatable chain extension terminators. The invention also relates to the use of the compounds (I) in nucleic acid synthesis and nucleic acid sequencing as well as to a method of preparing compounds of Formula (I).

专利号:DE-69627314-T2
优先权日:1995-01-31
标题:CHAIN TERMINATION GROUPS, THEIR USE FOR SEQUENCING AND SYNTHESIS OF NUCLEIC ACIDS, AND METHOD FOR THE PRODUCTION THEREOF

专利号:EP-0808320-A1
优先权日:1995-01-31
标题:Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

专利号:WO-9623807-A1
优先权日:1995-01-31
标题:Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation

专利号:EP-0808320-B1
优先权日:1995-01-31
标 题 :Novel chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation