(4,6-Dimethylpyrimid-2'-yl)-Trimethylammonium Chloride置于乙酰胺,盐酸,水体系中,化学反应生成4,6-二甲基嘧啶 参考文献:Heteroarylierungen Mit Quartrsubstituierten Pyrimidinsalzen 标题:Heteroarylierungen Mit Quartrsubstituierten Pyrimidinsalzen 摘要: Doi:10.1007/bf00917846
专利信息
专利号:US-4866175-A 优先权日:1966-11-08 标 题 :Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides 发明人:ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J 权利人:RESEARCH CORP 摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.
专利号:US-4343942-A 优先权日:1966-11-08 标题:Quinoxaline derivatives 发明人:ISSIDORIDES COSTAS H; HADDADIN MAKHLUF J 权利人:RESEARCH CORP 摘要:The synthesis of quinoxaline and benzimidazole-N-oxides and of ester and amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a novel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under basic conditions.
专利号:EP-3070087-B1 优先权日:2011-08-05 标题 :Intermediates for the synthesis of cyclic p1 linkers as factor xia inhibitors
专利号:EP-3070087-A1 优先权日:2011-08-05 标 题 :Intermediates for the synthesis of cyclic p1 linkers as factor xia inhibitors
专利号:US-11518933-B2 优先权日:2016-05-25 标题:Precursor based method of synthesis and fabrication of hybrid lighting phosphors with high quantum efficiency, and significantly enhanced thermal and photostability 发明人:LI JING; FANG YANG; LIU WEI 权利人:UNIV RUTGERS 摘要:Highly thermal and photo-stable inorganic-organic hybrid phosphor compounds, in which a copper (I) halide module is coordinated with a multi-dentate organic ligand. Also disclosed are semiconductor and light emitting devices comprising these materials, including light emitting diodes, and methods of preparing these materials and devices.
专利号:US-6936600-B2 优先权日:1999-04-01 标题:Sorbitol dehrydrogenase inhibitors 发明人:CHU-MOYER MARGARET Y; MYLARI BANAVARA L; ZEMBROWSKI WILLIAM J 权利人:PFIZER 摘要:This invention is directed to sorbitol dehydrogenase inhibitory compounds of the formula I, n n nwherein R 1 , R 2 and R 3 are as defined in the specification. This invention is also directed to pharmaceutical compositions containing those compounds and methods of treating or preventing diabetic complications, particularly diabetic neuropathy, diabetic nephropathy, diabetic microangiopathy, diabetic macroangiopathy and diabetic cardiomyopathy by administering such compounds to a mammal suffering from diabetes and therefore at risk for developing such complications. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an aldose reductase inhibitor and to methods of treating or preventing diabetic complications therewith. This invention is also directed to pharmaceutical compositions comprising a combination of a compound of formula I of this invention with an NHE-1 inhibitor and to methods of treating cardiomyopathy and other heart-related problems therewith. This invention is also directed to certain intermediates used in the synthesis of the compounds of formula I and to processes for preparing those intermediates.
参考文献:10.1107/s1600536811012323 摘要:Saeed S, Rashid N, Wong WT, Hussain R. 1-(4,6-Dimethyl-pyrimidin-2-yl)-3-(3,5-dinitro-benzo-yl)thio-urea monohydrate. Acta Crystallogr Sect E Struct Rep Online. 2011 May 01;67(Pt 5):o1094.