CAS: 149-29-1; Patulin

上下游产品

Aspergilsmin C 123251-09-2
(S)-展青霉素甲基醚 (S)-O-Methylpatulin 123251-09-2
Ascladiol 32013-85-7

📜2,2-Dimethyl-Propionic Acid 4-Hydroxy-2-Oxo-2,6,7,7A-Tetrahydro-4H-Furo[3,2-C]Pyran-7-Yl Ester置于1,8-二氮杂双环[5.4.0]十一碳-7-烯体系中,用 二氯甲烷 用作溶剂,化学反应 0.75H,以70%的收率获得棒曲霉素
参考文献:抗生素棒曲霉素的有效全合成
标题:抗生素棒曲霉素的有效全合成
摘要:由6-(叔丁基二甲基甲硅烷氧基)-4-[(叔丁基二甲基甲硅烷氧基)-甲基]呋喃(2)和苄氧基乙醛(4)以六步合成(41.3%的总产率)有效的抗生素棒棒蛋白(1).
Doi:10.1016/0040-4039(95)01487-3

专利信息

专利号:US-4774173-A
优先权日:1984-12-06
标 题 :Microbiological assay kit and method for detecting de novo biomolecular synthesis inhibitors
发明人：REINHARTZ AVRAHAM
权利人:ORGENICS LTD
摘要:A method for assaying a specimen for the presence of a substance capable of inhibiting de novo biomolecular synthesis in a test microorganism, which comprises: exposing a cell wall permeability-enhanced test microorganism exhibiting delayed de novo synthesis of said biomolecule to said specimen, and assaying the extent of inhibition of synthesis of said biomolecule in said microorganism. A kit is described for performing the method, as well as a reaction mixture for performing the technique.

专利号:US-6887694-B1
优先权日:1999-01-29
标 题 :DNA encoding a polypeptide required for biosynthesis of TA antibiotic
发明人：ROSENBERG EUGENE; RON ELIORA; ORR ELISHA; PAITAN YOSSI
权利人:UNIV RAMOT
摘要:There is provided DNA sequences isolated from Myxococcus xanthus partially encoding a functional portion of a polypeptide component required for the synthesis of antibiotic TA. Also provided are purified, isolated and cloned DNA sequences encoding a polypeptide component required for postmodification of antibiotic TA and encoding a gene product involved in the regulation of the biosynthesis of antibiotic TA. A purified, isolated and cloned DNA sequence having a DNA sequence (seq. ID No:2 and 20) encoding a polypeptide component required for encoding the TA gene cluster and any mutations thereof is provided. Also provided are methods of using the TA genes for combinatorial genetics and of using the TA genes encoding for synthesis and modification or regulation of antibiotic TA.

专利号:US-2008108109-A1
优先权日:1999-01-29
标 题 :Biosynthesis of TA antibiotic
发明人：ROSENBERG EUGENE; RON ELIORA; ORR ELISHA; PAITAN YOSSI
权利人:UNIV RAMOT
摘要:A method of producing an antibiotic TA comprising (i) expressing in a host cell an exogenous polynucleotide sequence encoding at least one polypeptide selected from the group consisting of SEQ ID NOs: 1 and 3-19; and (ii) culturing the host cell under conditions suitable for synthesis of the antibiotic TA, thereby producing the antibiotic TA.

专利号:US-2022249576-A1
优先权日:2021-02-09
标 题:Method of disrupting mycotoxin synthesis using a composition comprising vibrio gazogenes
发明人：CHANDA ANINDYA
权利人:Mycologics LLC
摘要:A method of inhibiting mycotoxin synthesis in filamentous fungi comprises contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC. Additionally, infections caused by filamentous fungi can be inhibited by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942. Endosomal function in filamentous fungi can be disrupted by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942. Hyphal fusion formation can be restricted in filamentous fungi by contacting the filamentous fungi with a composition comprising Vibrio gazogenes, ATCC 43942.

专利号:US-11612878-B2
优先权日:2018-07-25
标题 :Synthesis and application of a nanomaterial for removal of patulin
发明人：SUN XIULAN; YE YONGLI; JI JIAN; PI FUWEI; ZHANG YINZHI; GUO WEI; SHAN XUEQING
权利人:UNIV JIANGNAN
摘要:The present disclosure belongs to the technical field of analytical chemistry, in particular to synthesis and application of a nanomaterial for removal of patulin (Pat). The present disclosure adopts 2-Oxin as a substitute template, AM as a functional monomer, and synthetic Fe 3 O4@SiO 2 @CS-GO magnetic nanoparticles as a carrier, for preparing a magnetic MIP specific for Pat adsorption by surface imprinting. The addition of Fe 3 O 4 makes the finally prepared molecular imprinted adsorbent material magnetic, thereby facilitating separation of a material from a matrix, eliminating complicated operation steps such as filtration and centrifugation, and facilitating recovery of materials.

专利号:US-9719098-B2
优先权日:2011-04-05
标 题:Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors
发明人：ARGYROS AARON; SILLERS WILLIAM RYAN; BARRETT TRISHA; CAIAZZA NICKY; SHAW IV ARTHUR J
权利人:LALLEMAND HUNGARY LIQUIDITY MAN LLC
摘要:The present invention provides for novel metabolic pathways to reduce or eliminate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising a deletion of one or more native enzymes that function to produce glycerol and/or regulate glycerol synthesis and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous enzymes is activated, upregulated, or downregulated. The invention also provides for a recombinant microorganism comprising one or more heterologous enzymes that function to regulate glycerol synthesis and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source to ethanol, wherein said one or more native and/or heterologous enzymes is activated, upregulated or downregulated.