CAS: 131274-22-1; Tri-Tert-Butylphosphonium Tetrafluoroborate

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CAS号13716-12-6 三叔丁基膦 | CAS号677-22-5 叔丁基氯化镁

专利信息

专利号:WO-2025119975-A1
优先权日:2023-12-04
标 题:A method for synthesis of harmine
发明人：HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN
权利人:RECONNECT LABS AG
摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.

专利号:US-8288581-B2
优先权日:2008-07-17
标 题:Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO
权利人:PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO; SERVIER LAB; CENTRE NAT RECH SCIENT
摘要:Process for the preparation of compounds of formula (IV): n nwherein R 1 -R 6 are as defined in the specification.n n Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:EP-4186890-A1
优先权日:2021-11-29
标题 :Preparation of n-benzyl-2-(5-bromo-pyridin-2-yl)-acetamide for the synthesis of tirbanibulin
发明人：ARE CELESTE; BALLETTE ROBERTO; DOBARRO RODRÃ?GUEZ ALICIA
权利人:MOEHS IBERICA SL
摘要:The present invention relates to a process for the preparation of N-benzyl-2-(5-bromo-pyridin-2-yl)-acetamide, which is a suitable intermediate for the synthesis of tirbanibulin or a pharmaceutically acceptable salt thereof, as well as to a process for the preparation of tirbanibulin or a pharmaceutically acceptable salt thereof using said N-benzyl-2-(5-bromo-pyridin-2-yl)-acetamide intermediate.

专利号:US-2023183246-A1
优先权日:2020-05-19
标题 :Continuous flow sonogashira coupling synthesis method
发明人：THOMPSON DAVID HARLEY; SINTIM HERMAN O; QI QINGQING; BIYANI SHRUTI
权利人:PURDUE RESEARCH FOUNDATION
摘要:The present disclosure relates to a telescoped continuous flow Sonogashira coupling synthesis for some lead compounds to support in vivo studies and pre-clinical evaluation. The application of high throughput tools combined with the telescoped continuous synthesis method can enable an efficient and safe synthesis of compounds of interest involving hazardous coupling reagents such as HATU, while minimizing by-product formation.

专利号:US-11718584-B2
优先权日:2019-02-22
标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof
发明人：KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR
权利人:PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)

专利号:US-9379335-B2
优先权日:2012-04-08
标题:Benzodipyrrolidones and their polymers: synthesis and applications for organic electronics and optoelectronics
发明人：CUI WEIBIN; WUDL FRED
权利人:UNIV CALIFORNIA
摘要:Disclosed is the synthesis of benzodipyrrolidone and their polymers and small molecules for electronic and optoelectronic applications. Also disclosed are devices that incorporate such polymers and small molecules.