CAS: 112898-33-6; (E)-3-(2,5-Difluorophenyl)Acrylic Acid

相似化合物

451-69-4 18944-77-9 1007862-01-2

上下游产品

CAS号110-89-4 六氢吡啶 | CAS号2646-90-4 2,5-二氟苯甲醛 | CAS号399-94-0 2,5-二氟溴苯 | CAS号79-10-7 丙烯酸 | CAS号130408-15-0 3-(2,5-二氟苯基)丙酸 | CAS号566172-81-4 3-Chloro-4,7-di...

2,5-二氟溴苯,丙烯酸置于bis-Triphenylphosphine-Palladium(II) Chloride,Potassium Carbonate体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 6.0H,以10%的收率获得反式-2,5-二氟肉桂酸
参考文献:Aizikovich; Korotaev,Russian Journal Of Organic Chemistry,1997,Vol. 33,# 4,P. 563-564
标题:Aizikovich; Korotaev,Russian Journal Of Organic Chemistry,1997,Vol. 33,# 4,P. 563-564

专利信息

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-2012202787-A1
优先权日:2009-10-20
标 题:Novel Heteroaryl Imidazoles And Heteroaryl Triazoles As Gamma-Secretase Modulators
发明人：AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN
权利人:AM ENDE CHRISTOPHER WILLIAM; JOHNSON DOUGLAS SCOTT; PETTERSSON MARTIN YOUNGJIN; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I; n n n n n n n n n n as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:RU-2164913-C2
优先权日:1995-05-22
标 题:ALKENYLCARBOXYLIC ACID GUANIDIDES, METHOD OF THEIR SYNTHESIS, METHOD OF INHIBITION OF CELLULAR Na+/H+-EXCHANGE AND PHARMACEUTICAL COMPOSITION