CAS: 102-98-7; Boronooxy(Phenyl)Mercury

专利信息

专利号:US-2025009786-A1
优先权日:2021-09-30
标 题 :Automated synthesis of polymeric dual drugs
发明人：MATRAY TRACY; VANBRUNT MICHAEL; MCCUTCHEON JOHN MICHAEL
权利人:SONY GROUP CORP
摘要:Compounds useful as biologically active compounds with or without fluorescent or colored dyes are disclosed. In some embodiments, the compounds have the following structure (I): (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, L1, L2, L3, L4, L5, L6, L7, L8, L9, L10, L11, M1, M2, M3, l, m, n, p, and q are as defined herein. Additional compound, methods of preparation, pharmaceutical compositions, and methods of treatment related to compounds of Structure (I) are also provided.

专利号:US-11718596-B2
优先权日:2014-03-19
标题 :Amyloid targeting agents and methods of using the same
发明人：YANG JERRY; THEODORAKIS EMMANUEL A; SARRAF STELLA
权利人:UNIV CALIFORNIA; AMYDIS INC
摘要:Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

专利号:WO-2023002431-A1
优先权日:2021-07-22
标 题:Automated synthesis of polymeric drugs

专利号:US-2008057128-A1
优先权日:2003-07-18
标 题:Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from
发明人：LI JUN; LI XU; NI XIPING; LEONG KAM W
权利人:OMEROS CORP
摘要:A drug delivery system that includes micelles formed from an amphiphilic copolymer that includes an A polymer block comprising a poly(alkylene oxide) and a B polymer block comprising a poly(hydroxyalkanoate), and a therapeutically effective amount of at least one therapeutic agent intimately contained within the micelles. In one preferred embodiment of the invention, the A polymer block is poly(ethylene oxide) (PEO) and the B polymer block is poly[(R)-3-hydroxybutyrate] (PHB), and the copolymer is the triblock ABA copolymer PEO-PHB-PEO. A method of synthesizing the amphiphilic triblock copolymer is also provided.

专利号:WO-2023052971-A1
优先权日:2021-09-30
标题 :Automated synthesis of polymeric dual drugs

专利号:US-7297348-B2
优先权日:2002-07-19
标 题 :Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from
发明人：LI JUN; LI XU; NI XIPING; LEONG KAM W
权利人:OMEROS CORP; INST MATERIALS RESEARCH & ENG
摘要:A drug delivery system that includes a hydrogel formed from cyclodextrin and an amphiphilic copolymer that includes an A polymer block comprising a poly(alkylene oxide) and a B polymer block comprising a poly(hydroxyalkanoate), and a therapeutically effective amount of at least one therapeutic agent intimately contained within the hydrogel. In one preferred embodiment of the invention, the A polymer block is poly(ethylene oxide) (PEO) and the B polymer block is poly[(R)-3-hydroxybutyrate] (PHB), and the copolymer is the triblock ABA copolymer PEO-PHB-PEO. A method of synthesizing the amphiphilic triblock copolymer is also provided.