CAS: 10030-80-5; (2R,3R,4S,5S)-2,3,4,5,6-Pentahydroxyhexanal

上下游产品

CAS号7251-85-6 1,6-Dichloro-1,...

📜L-阿拉伯糖置于吡啶,氢氰酸体系中,化学反应生成L(-)-甘露糖
参考文献:Kuhn; Klesse,Chemische Berichte,1958,Vol. 91,P. 1989
标题:Kuhn; Klesse,Chemische Berichte,1958,Vol. 91,P. 1989

专利信息

专利号:US-2023212216-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins
发明人：MORRIS ALEXANDER REDFERN; SUTOV GRIGORIJ; BRUNE KARL DIETRICH
权利人:GENIE BIOTECH UK LTD
摘要:Site-specific modifications of proteins are desirable in biotechnological applications such as biopharmaceuticals, immunotherapy, vaccines, and are useful in chemical biology. Gluconoylation is a non-enzymatic, covalent, post-translational modification commonly observed on N-terminal His-Tags bearing proteins. We synthesized glucono-1,5-lactone derivatives, including azido variants for selective acylation. High yield acylation is achieved by simply mixing derivatives with target protein amidst diverse conditions of temperatures, aqueous buffers, excipients, or complex cell lysate.

专利号:US-8697416-B2
优先权日:2002-08-26
标 题:Recombinant polynucleotide, host cells containing the same and a process for producing a protein having aldolase activity
发明人：SUGIYAMA MASAKAZU; WATANABE KUNIHIKO; KAWAHARA SHIGERU
权利人:SUGIYAMA MASAKAZU; WATANABE KUNIHIKO; KAWAHARA SHIGERU; AJINOMOTO KK
摘要:4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus Pseudomonas, Erwinia, Flavobacterium , or Xanthomonas.

专利号:AU-2020409711-A1
优先权日:2019-12-20
标题 :Synthesis of lactone derivatives and their use in the modification of proteins

专利号:EP-4076533-A1
优先权日:2019-12-20
标 题:Synthesis of lactone derivatives and their use in the modification of proteins

专利号:WO-9619438-A1
优先权日:1994-12-22
标 题 :An enantioselective synthesis of certain hydroxylamines

专利号:US-11248016-B2
优先权日:2014-04-04
标 题:Glycolipids and pharmaceutical compositions thereof for use in therapy
发明人：BOTTLEY ANDREW; HAYES CHRISTOPHER; SEYMOUR GRAHAM; GRABOWSKA ANNA; CLARKE PHILIP
权利人:UNIV NOTTINGHAM
摘要:The invention may provide, in part, compounds for use as antiproliferative, chemotherapeutic, antiviral, cell sensitising or adjuvant agents, and pharmaceutical compositions including the compounds. The compounds may be for use in treating diseases and disorders related to cell proliferation such as cancer, or in treating diseases and disorder which are linked to aberrant control of protein synthesis, such as cancer, viral infection, muscle wasting, autistic spectrum disorders, Alzheimer's disease, Huntingdon's disease and Parkinson's disease.