CAS: 67416-61-9; (3R,4R,4Ar,6Ar,6Bs,8Ar,11R,12S,12Ar,14Ar,14Bs)-3-Acetoxy-4,6A,6B,8A,11,12,14B-Heptamethyl-14-Oxo-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,14,14A,14B-Icosahydropicene-4-Carboxylic Acid

上下游产品

CAS号631-69-6 β-乳香酸 | CAS号17019-92-0 11-氧代-β-乳香酸 | CAS号5968-70-7 3-O-乙酰基-β-乳香酸 | CAS号108-24-7 乙酸酐 | CAS号17019-92-0 11-氧代-β-乳香酸

📜3-乙酰基-Beta-乳香酸置于n-溴代丁二酰亚胺(Nbs),水,Calcium Carbonate体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 4.0H,反应生成 乙酰基-11-酮基-Beta-乳香酸
参考文献:一种大规模制备 3-O-Acetyl-11-Oxo-β-乳香酸和其他乳香酸的有效方法
标题:一种大规模制备 3-O-Acetyl-11-Oxo-β-乳香酸和其他乳香酸的有效方法
摘要:3-O-Acetyl-11-Oxo-β-Boswellic Acid (Akba) 存在于香中,是 5-脂氧合酶,P38 和 P42 Map 激酶和拓扑异构酶的有效抑制剂.从熏香的粗提取物开始,介绍了高效大规模合成 Akba 和其他乳香酸的程序(© Wiley-Vch Verlag Gmbh & Co. Kgaa,69451 Weinheim,德国,2003 年)
DOI:10.1002/ejoc.200300386

专利信息

专利号:US-2006234990-A1
优先权日:1999-04-30
标题 :Compositions of boswellic acids derived from Boswellia serrata gum resin, for treating lymphoproliferative and autoimmune conditions
发明人：MAJEED MUHAMMED; BADMAEV VLADIMIR
权利人:SAMI LABS LTD
摘要:A method of treatment of lymphoproliferative and autoimmune disorders with a new composition of four boswellic acids including β-boswellic acid, 3-O-acetyl-β-boswellic acid, 11-keto-β-boswellic acid, and 3-O-acetyl-11-keto-β-boswellic acid. Boswellic acids of invention have been obtained in a novel industrial process from the gum resin of Boswellia serrata tree, providing standardized composition which inhibits DNA, RNA and protein synthesis of the target cell without cytotoxic effects. The composition of invention provides advantage of irreversible cytostatic therapy, equivalent to biological effects of a cytotoxic therapy without killing body cells.

专利号:WO-2008058514-A1
优先权日:2006-11-14
标 题:Preparations comprising boswellic acids for inhibiting the synthesis of prostaglandin e2
发明人：WERZ OLIVER; SIEMONEIT ULF
权利人:UNIV EBERHARD KARLS; WERZ OLIVER; SIEMONEIT ULF
摘要:The present invention relates to the use of preparations with pentacyclic triterpenoic acids and structural derivatives thereof, in particular boswellic acids from Boswellia species (such as B. serrata, B. carterii, B. sacra), for inhibiting the inducible mitochondrial prostaglandin E₂ synthase-1. In addition, the invention relates to the use of pentacyclic triterpenoic acids and derivatives thereof for producing a medicament for the treatment of PGE₂-mediated diseases.

专利号:US-2008281105-A1
优先权日:2005-01-18
标题:Novel Quinolinium Salts and Derivatives
发明人：MACDONALD JAMES E; HYSELL MICHELLE K; YU DEHUA; LI HENRY; WONG-STAAL FLOSSIE
权利人:IMMUSOL INC
摘要:The present invention relates generally to the synthesis of novel quinolinium salts and derivative compounds. Such salts and compounds are useful for inhibiting the growth of cancer cells.

专利号:EA-002100-B1
优先权日:1996-12-23
标题:CYCLOALCYL COMPOUNDS, LACTAMS, LACTONES AND RELATED COMPOUNDS CONTAINING THEIR PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING THE SURVIVAL AND / OR SYNTHESIS OF β-AMYLOUS PEPTIDE SOFTWARE AGREED SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE, SOFTWARE AND SOFTWORK

专利号:WO-02085921-A2
优先权日:2001-03-01
标 题 :Simple method for the synthesis of boswellic acids and derivatives thereof

专利号:CN-120004968-A
优先权日:2023-11-15
标 题:Synthesis of AKBA derivative and application thereof in glioma resistance