CAS: 20529-23-1; 3-(4-(2-Methoxyphenyl)Piperazin-1-yl)Propan-1-Amine

上下游产品

3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propionitrile urapidil 2-(3-bromopropyl)isoindole-1,3-dione 1-(2-Methoxyphenyl)piperazine 2-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-5-sulfamoyl-benzamide 2-Amino-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-acetamide 2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N-dimethylnicotinamide

📜在 盐酸体系中,化学反应生成1-(3-氨基)-4-(2-甲氧基苯基)哌嗪
参考文献:A Simple And Efficient Synthesis Of A Derivatized Pseudotripeptide Containing A Methylene Thioether Isostere And Its Use For The Design Of Bifunctional Rhenium And Technetium Chelating Agents
标题:A Simple And Efficient Synthesis Of A Derivatized Pseudotripeptide Containing A Methylene Thioether Isostere And Its Use For The Design Of Bifunctional Rhenium And Technetium Chelating Agents
摘要:A New Approach To A Pseudotripeptide Based Tetradentate Chelating Unit Functionalizable With Various Bioactive Groups Has Been Developed. Using A One-Pot Reaction,A Given Omega-Aminoalkyl Compound Has Been Converted To A Methylene Thioether Peptide Isostere By Two Consecutive Ring Opening Reactions. (C) 1997 Elsevier Science Ltd.
Doi:10.1016/s0040-4039(97)00083-X

专利信息

专利号:WO-2005021506-A1
优先权日:2003-08-28
标题:Synthesis of 1-[4-(2-methoxyphenyl) piperazin-1-yl]-3-(2,6-dioxopiperidin-1-yl) propane
发明人：YADAV GYAN CHAND; SHARMA SOMESH; SALMAN MOHAMMAD
权利人:RANBAXY LAB LTD; YADAV GYAN CHAND; SHARMA SOMESH; SALMAN MOHAMMAD
摘要:The present invention relates to syntheses of 1-[4-(2-methoxyphenyl)piperazin-1-yl]-(2,6-dioxopiperidin-1-yl)propane and its pharmaceutically acceptable salts, preferably hydrochloride having protracted uro-selective α1-adrenoceptor antagonistic activity. The compound holds promise for treating benign prostatic hyperplasia (BPH).

专利号:US-6387909-B1
优先权日:1999-07-30
标 题 :Thienopyranecarboxamide derivatives
发明人：LEONARDI AMEDEO; MOTTA GIANNI; RIVA CARLO; TESTA RODOLFO
权利人:RECORDATI CHEM PHARM
摘要:The invention relates to novel N-(substituted phenyl)-N'-[omega-(5-substituted-7-oxo-7H-thieno[3,2-b]pyran-3-carbonylamino)alkyl]piperazines their N-oxides and pharmaceutically acceptable salts thereof. The compounds are endowed with enhanced selectivity for alpha1-adrenergic receptors and a low activity in lowering blood pressure. The compounds are useful in the treatment of obstructive syndromes of the lower urinary tract, including benign prostatic hyperplasia (BPH), and in the treatment of lower urinary tract symptoms (LUTS) and neurogenic lower urinary tract dysfunction (NLUTD). The compounds are also useful in the treatment of excessive intraocular pressure, cardiac arrhythmia, erectile dysfunction, sexual dysfunction, and for inhibiting cholesterol synthesis or reducing sympathetically mediated pain.

专利号:WO-2008144764-A1
优先权日:2007-05-21
标 题 :Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

专利号:AU-2008254585-B2
优先权日:2007-05-21
标 题:Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents

专利号:US-2008293736-A1
优先权日:2007-05-21
标 题:Compositions, Synthesis, and Methods of Using Quinolinone Based Atypical Antipsychotic Agents

专利号:US-8247420-B2
优先权日:2007-05-21
标 题:Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents
发明人：BHAT LAXMINARAYAN; MOHAPATRA PRABHU P; BHAT SEEMA RANI
权利人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU P; BHAT SEEMA RANI; REVIVA PHARMACEUTICALS INC
摘要:The present invention provides novel quinolinone derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder, and depression.