CAS: 13788-92-6; 1-(4-Bromophenyl)-1H-Pyrazole

该化合物是一个有机化合物,其特点是有五人环,含有两个相邻的氮原子,由五人环组成;在Pyraole结构的1位置上存在一个溴联苯集团,这对其独特性起到了作用;该化合物通常是一种固体,因其在医药化学领域的潜在应用而闻名,特别是因其生物活动而在药物开发方面的潜在应用;它可能表现出与生物目标的各种相互作用,从而引起对......

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相似化合物

294877-33-1 1184673-82-2 98946-73-7

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号288-13-1 吡唑 | CAS号589-87-7 对溴碘苯 | CAS号106-37-6 对二溴苯 | CAS号460-00-4 对氟溴苯 | CAS号102-52-3 1,1,3,3-四甲氧基丙烷 | CAS号589-21-9 4-溴苯基肼

合成工艺路线路线简述

  • 288-13-1 = 13788-92-6 + 87488-84-4
    反应条件:1.1 Reagents: Acetic Acid,Lithium Perchlorate Catalysts: Cyclopropenylium,1,2,3-Tris[(2R,6S)-2,6-Dimethyl-1-Piperidinyl]-,Rel-,Perchlo... Solvents: Acetonitrile; 96 H,Rt
    标题:Electrophotocatalysis With A Trisaminocyclopropenium Radical Dication
    作者:Huang,He; Et Al
    参考文献:Angewandte Chemie 日期:2019 卷标:58(38) 页码:13318-13322
📜(E)-3-(2-Methylaziridin-1-yl)Prop-2-Enal 以43%的收率获得
参考文献:Eremeev A. V.; Tixomirov D. A.; Tyusheva V. A.; Liepinsh Eh. Eh.,Ximiya Geterotsikl. Soedin.,1978,Ho 4,483-488
标题:Eremeev A. V.; Tixomirov D. A.; Tyusheva V. A.; Liepinsh Eh. Eh.,Ximiya Geterotsikl. Soedin.,1978,Ho 4,483-488

专利信息


专利号:US-10226449-B2
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof
发明人:HEUER TIMOTHY SEAN; OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREGORY; OHOL-GUPTA YAMINI; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

专利号:US-9428502-B2
优先权日:2012-07-03
标题:Heterocyclic modulators of lipid synthesis
发明人:OSLOB JOHAN D; MCDOWELL ROBERT S; JOHNSON RUSSELL; YANG HANBIAO; EVANCHIK MARC; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; WAGMAN ALLAN S
权利人:3-V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by disregulation of a fatty acid synthase pathway by the administration of such compounds.

专利号:US-2018222892-A1
优先权日:2012-07-03
标 题 :Heterocyclic modulators of lipid synthesis

专利号:EP-3083583-B1
优先权日:2013-12-20
标 题:Heterocyclic modulators of lipid synthesis and combinations thereof

专利号:EP-3083583-A1
优先权日:2013-12-20
标题 :Heterocyclic modulators of lipid synthesis and combinations thereof

专利号:CA-2934251-C
优先权日:2013-12-20
标 题:A combination of heterocyclic modulators of lipid synthesis and chemotherapeutic drugs in treatment of cancer

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✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Götzinger, A. C.; Müller, T. J. J., Science of Synthesis Knowledge Updates, (2017) 3, 188.
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