CAS: 77-65-6; 2-Bromo-N-Carbamoyl-2-Ethylbutanamide

该化合物是一种有机酒精,其特点是其分支链结构的有机酒精,其特性是其独特的物理和化学特性.它通常是一种无色液体,其气味较轻.氢氧基(OH)功能组的存在将它归类为酒精,影响其在水中的溶解性及其在各种化学反应中的再活性.2,4-二甲基-3-pentanol被用于有机合成,并可作为其他化学化合物生产的中间体.其沸点和熔点受到分子结构的影响,该分子结构影响其挥发性和相行为.安全数据表明,与许多有机溶剂一样,应谨慎处理,以避免吸入或皮肤接触.

结构式图片

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

上下游产品

methanol N,N'-bis-(2-ethyl-2-bromo-butyryl)-ureaN,N'-bis-(2-ethyl-2-bromo-butyryl)-urea N-carbamoyl-2-ethylbutyraldehyde 2-ethyl-butyryl is°Cyanate cis-2-Ethyl-crotonylharnstoff N-carbamoyl-2-ethylbutyraldehyde 2-ethyl-2-butenoic acid (2Z)-2-ethyl-2-butenoic acid

合成工艺路线路线简述

  • 合成目标产物 (2-Bromo-2-Ethylbutyryl)Urea 主要起始原料 2-Bromo-2-Ethylbutyryl Bromide
  • (文献来源)合成步骤主要原料 2-Bromo-2-Ethylbutyryl Bromide
📜N-氨基甲酰基-2-乙基丁酰胺置于溴体系中,化学反应生成 乙溴酰脲
参考文献:De225710
标题:De225710

海关参考信息

专利信息


专利号:US-7247752-B2
优先权日:2004-10-01
标 题 :Methods for the synthesis of astaxanthin
发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.

专利号:WO-2009018504-A1
优先权日:2007-08-01
标题 :Process for the synthesis of diaminopyridine and related compounds
发明人:RITTER JOACHIM C
权利人:DU PONT; RITTER JOACHIM C
摘要:A process is provided for the synthesis of a diaminopyridine, such as 2,6-diaminopyridine and related compounds, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a chlorine-ammonia displacement in the presence of a copper source.

专利号:US-9388131-B2
优先权日:2011-04-27
标题:Automated synthesis of small molecules using chiral, non-racemic boronates
发明人:BURKE MARTIN D; LI JUNQI; GILLIS ERIC P
权利人:UNIV ILLINOIS
摘要:Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification.

专利号:WO-2023012709-A1
优先权日:2021-08-05
标 题 :An improved process for fmoc synthesis of semaglutide
发明人:LOBO LESTER JOHN; CHANDRAKESAN MURALIDHARAN; DOSHI CHETAN; CHANADAK SHAILESH LALCHAND; YADAV NANDLAL GOPAL; MOHE NIKHIL UMESH; VISHWANATHAN KODANDARAMAN
权利人:USV PRIVATE LTD
摘要:The present invention relates to an improved process for the synthesis of glucagon-like-peptide-1 (GLP-1) and its analogs by using combination of solid and solution phase synthesis of Fmoc protected amino acids in a sequential manner, optionally incorporating Boc protected dipeptide for unnatural amino acid in the Sequence of GLP-1, cleaving GLP-1 sequence from the resin followed by purification; attaching side-chain to the desired amino acid in the solution phase to synthesize desired GLP-1 analog, purifying it to Semaglutide. Temperature gradient is applied during initial coupling of amino acids to facilitate completion of difficult coupling reactions.

专利号:US-6376676-B1
优先权日:1993-06-30
标题 :Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof
发明人:CURRAN DENNIS P; LIU HUI
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of novel intermediates in the synthesis of (±)-camptothecin and related compounds. The present synthesis scheme includes a novel 4+1 radical annulation followed by another cyclization to simultaneously assemble rings B and C of the camptothecin compound. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-11891351-B2
优先权日:2020-03-20
标 题 :Synthesis of capsaicin derivatives
发明人:LAGER ERIK
权利人:AXICHEM AS
摘要:The present invention relates to the synthesis of capsaicin derivatives, specifically to the synthesis of 6-heptyne derivatives of capsaicin.

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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Oehmichen M, Ochs U, Meissner C. Regional potassium distribution in the brain in forensic relevant types of intoxication preliminary morphometric evaluation using a histochemical method. Neurotoxicology. 2001 Feb;22(1):99-107. German. German. German. German. German. German. German. German. German.

合成参考文献


摘要:Clinical and Experimental Pharmacology and Physiology., 3(443), 1976 []
摘要:Journal of the American Pharmaceutical Association., 23(788), 1934
摘要:Archives of Toxicology., 40(211), 1978 []
摘要:Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals, 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989, 11(278), 1989
摘要:Testa, B. and P. Jenner. Drug Metabolism: Chemical & Biochemical Aspects. New York: Marcel Dekker, Inc., 1976., p. 168
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