CAS: 691-57-6; 2-Azidopropane

该化合物是有机化合物,其特点是附于一个分支烷基链的Azide功能组(-N3),其分子式为C4H8N3, 其分子重量相对较低;该化合物一般是室内温度下无色液体,具有独特的气味. 已知1-甲基乙基乙基硫化物具有较高的反应性,特别是由于该亚齐德组的存在,该组可能发生分解并导致氮气的释放.这种特性在一定条件下具有爆炸性潜力,需要小心处理和储存.此外,该化合物在有机溶剂中可溶解,但水溶性有限.该化合物主要用于有机合成,特别是各种含氮化合物的制造.由于该化合物具有再活性和潜在危险,在实验室环境中与1-甲基乙酰胺合作时应采取适当的安全措施.

结构式图片

MSDS等安全信息

上下游产品

CAS号75-26-3 2-溴丙烷 | CAS号75-31-0 异丙胺 | CAS号87549-57-3 1-Propanamine, ... | CAS号74-98-6 丙烷 | CAS号38697-07-3 propan-2-imine | CAS号74-90-8 氢氰酸 | CAS号75-05-8 乙腈 | CAS号40168-14-7 triphenyl(propa...

合成工艺路线路线简述

    📜异丙胺置于碳酸氢钠,Perfluorobutanesulfonyl Azide,Copper(II) Sulfate体系中,用 甲醇,乙醚,水 作为反应溶剂,化学反应生成 2-叠氮基丙烷
    参考文献:"单击"双三唑为中性c吗h⋅⋅⋅阴离子受体有机催化剂
    标题:"单击"双三唑为中性c吗h⋅⋅⋅阴离子受体有机催化剂
    摘要:球场上的新球员!"点击"双-三唑已被引入作为高效率的新型类中性的c  H⋅⋅⋅anion结合有机催化剂(参见方案).dft和NMR研究用于确认这种活化方式并确定最佳催化剂.
    DOI:10.1002/chem.201203360

    专利信息


    专利号:US-2024024497-A1
    优先权日:2020-08-06
    标 题:Methods for the synthesis of protein-drug conjugates
    发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
    权利人:CIDARA THERAPEUTICS INC
    摘要:The present invention relates to methods for the synthesis of conjugates useful for the treatment of viral infections, e.g., conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir or an analog thereof) linked to an Fc domain monomer.

    专利号:US-8268936-B2
    优先权日:2005-01-04
    标题:Synthesis of hybrid block copolymers and uses thereof
    发明人:BREITENKAMP KURT; SILL KEVIN N
    权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
    摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

    专利号:US-2012196989-A1
    优先权日:2005-02-11
    标题:Synthesis of homopolymers and block copolymers
    发明人:BREITENKAMP KURT; SILL KEVIN N
    权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
    摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.

    专利号:US-2023364251-A1
    优先权日:2020-08-06
    标 题:Methods for the synthesis of protein-drug conjugates
    发明人:BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
    权利人:CIDARA THERAPEUTICS INC
    摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

    专利号:US-5629394-A
    优先权日:1992-12-17
    标 题 :Direct synthesis by living cationic polymerization of nitrogen-containing polymers
    发明人:CHERADAME HERVE M; CHEN FRANK J; STANAT JON E R; NGUYEN HUNG A; TABAR BEHROOZ R
    权利人:EXXON CHEMICAL PATENTS INC
    摘要:A method is provided for the direct synthesis by living cationic polymerization of novel polymeric materials functionalized with desirable nitrogen-containing functional groups such as terminal azido, cyano, carbonylamino, cyanato, thiocyanato or thiocarbonylamino groups. Polymerization and functionalization occur in a substantially simultaneous manner. All necessary reactants for the functionalization are present when polymerization is initiated. The nitrogen-containing functional group is provided as a part of a molecule having a release moiety which is preferably resonance stabilized or a tertiary alkyl type and which acts to aid the nitrogen-containing species in functioning as a leaving group.

    专利号:US-2006172914-A1
    优先权日:2005-01-04
    标题:Synthesis of hybrid block copolymers and uses thereof

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 238.
    摘要:Kilah, N. L.; Wild, S. B., Science of Synthesis, (2009) 42, 627.
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