CAS: 554-68-7; Triethylamine Hydrochloride

相似化合物

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CAS号64-17-5 乙醇 | CAS号131933-37-4 2,3-bis(phenylm... | CAS号96-53-7 2-巯基噻唑啉 | CAS号4856-97-7 2-羟甲基苯并咪唑 | CAS号814-49-3 氯磷酸二乙酯 | CAS号96-45-7 乙撑硫脲 | CAS号75-94-5 乙烯基三氯硅烷 | CAS号121-44-8 三乙胺 | CAS号67-64-1 丙酮 | CAS号55-18-5 N-二乙基亚硝胺 | CAS号1112-67-0 四丁基氯化铵(TBAC) | CAS号14999-75-8 N,N-diethyletha... | CAS号1722-26-5 三乙胺-硼烷 | CAS号75-77-4 三甲基氯硅烷 | CAS号999-97-3 六甲基二硅氮烷 | CAS号994-28-5 三乙基氯化锗 | CAS号56-34-8 四乙基氯化铵 | CAS号56-37-1 三乙基苄基氯化铵(TEBAC)

N,N-二乙基氯乙胺置于三乙胺体系中,用 丙酮 作为反应溶剂,化学反应生成 三乙胺盐酸盐
参考文献:2-Or 3 Keto-3-Or-2-Phenyl-1,4-Disubstituted Piperazines
标题:2-Or 3 Keto-3-Or-2-Phenyl-1,4-Disubstituted Piperazines
摘要:1,4-取代苯基哌嗪化合物对血液凝固具有显著影响,并且在治疗血栓性疾病,尤其是动脉系统的治疗中非常有用.它们特别用于抑制冠状动脉或脑动脉的血栓形成.这类化合物的示例包括1-苯基(较低)烷基-2-苯基-3-酮基-4-双(较低)烷基氨基(较低)烷基哌嗪,1-苯基(较低)烷基-2-酮基-3-苯基-4-双(较低)烷基氨基(较低)烷基哌嗪,1-苯基(较低)烷基-2-苯基-4-双烷基氨基(较低)烷基哌嗪,1-苯基(较低)烷基-3-苯基-4-双(较低)烷基氨基(较低)烷基哌嗪及其药学上可接受的酸盐.1-位置的苯环可能被卤素,三氟(较低)烷基,较低烷氧基或苯基较低烷氧基取代;4-位置的双(较低)烷氨基(较低)烷基基团可能被哌啶(较低)烷基,吗啉(较低)烷基,吡咯啉(较低)烷基,哌嗪(较低)烷基等单核氮杂环取代(较低)烷基所替代.

专利信息

专利号:US-6683189-B1
优先权日:1996-02-26
标 题 :Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
发明人：DERVAN PETER B; BAIRD ELDON
权利人:CALIFORNIA INST OF TECHN
摘要:The present invention describes a novel method for the solid phase synthesis of polyamides containing imidazole and pyrrole carboxamides. The polyamides are prepared on a solid support from aromatic carboxylic acids and aromatic amines with high stepwise coupling yields (>99%), providing milligram quantities of highly pure polyamides. The present invention also describes the synthesis of analogs of the natural products Netropsin and Distamycin A, two antiviral antibiotics. The present invention also describes a novel method for the solid phase synthesis of imidazole and pyrrole carboxamide polyamide-oligonucleotide conjugates. This methodology will greatly increase both the complexity and quantity of minor-groove binding polyamides and minor-groove binding polyamide-oligonucleotide conjugates which can be synthesized and tested.

专利号:US-10189803-B2
优先权日:2008-02-22
标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-2008032964-A1
优先权日:2006-04-10
标题:Process for the synthesis of azetidinone
发明人：KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
权利人:KANSAL VINOD K; AHMAD SUHAIL; MARIAPPAN SHANMUGAVEL; TYAGI BHUPENDRA; PERLMAN NURIT; LE PAIH JACQUES; ZANOTTI-GEROSA ANTONIO
摘要:Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis of 1-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)-hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-11479577-B2
优先权日:2016-05-18
标题:Intermediates for the synthesis of bile acid derivatives, in particular of obeticholic acid
发明人：WEYMOUTH-WILSON ALEXANDER; KOMSTA ZOFIA; WALLIS LAURA; EVANS TIMOTHY; DAVIES IEUAN; OTTER CARL; BATCHELOR RHYS
权利人:NZP UK LTD
摘要:The present invention relates to compounds which are intermediates in the synthesis of bile acid derivatives with pharmacological activity. The invention relates to compounds of general formula (I):wherein:, R1, R2, R3, R4, R5, R6 and Y are as defined herein.The compounds are intermediates in the synthesis of synthetic bile acids which are useful in the treatment of conditions such as liver disease. In addition, the invention relates to a method of synthesizing these intermediates and a method of preparing obeticholic acid and obeticholic acid analogues from the compounds of the invention.

专利号:US-6207858-B1
优先权日:1999-03-03
标 题 :Regioselective synthesis of DTPA derivatives
发明人：CHINN PAUL; GYORKOS ALBERT; LABARRE MICHAEL J; RUHL STEVE; RYSKAMP THOMAS
权利人:IDEC PHARMA CORP
摘要:The present invention provides a process for high yield regioselective synthesis of DTPA derivatives that eliminates the need for ion exchange chromotographic separation of intermediates. Moreover, as this process yields a single regioisomer of the chelate, it provides for the regiospecific synthesis of desired chelates useful as radiolabeling agents.