CAS: 399-76-8; 5-Fluoroindole-2-Carboxylic Acid

上下游产品

CAS号348-36-7 5-氟吲哚-2-甲酸乙酯 | CAS号823-85-8 4-氟苯肼盐酸盐 | CAS号371-40-4 4-氟苯胺 | CAS号351-64-4 Propanoic acid,... | CAS号20893-71-4 4-fluorobenzene... | CAS号348-36-7 5-氟吲哚-2-甲酸乙酯 | CAS号443-73-2 5-氟吲哚-3-乙酸 | CAS号399-52-0 5-氟吲哚 | CAS号343-90-8 5-氟芦竹碱 | CAS号220941-93-5 5-氟-2-{[4-(2-吡啶... | CAS号167631-84-7 5-氟吲哚-2-甲酸甲酯 | CAS号79112-09-7 1H-INDOLE-2-CAR... | CAS号99532-53-3 1-(5-Fluoro-1H-... | CAS号518059-66-0 5-fluoro-N-(3-h...

(5-Fluoro-2-Nitro-Phenyl)-Pyruvic Acid置于ammonium Hydroxide,Iron(II) Sulfate体系中,化学反应生成 5-氟吲哚-2-甲酸
参考文献:Bergmann; Pelchowicz,Journal Of The Chemical Society,1959,P. 1913
标题:Bergmann; Pelchowicz,Journal Of The Chemical Society,1959,P. 1913

专利信息

专利号:US-11572354-B2
优先权日:2018-01-10
标题 :Inhibitor of indoleamine 2,3-dioxygenase-1 and methods of manufacture and use thereof
发明人：WEAVER DONALD; BRANT MICHAEL G; WOHNIG STEPHANIE; WU FAN; GOODWIN-TINDALL JAKE; MEEK AUTUMN; SCHIAVINI PAOLO
权利人:UNIV HEALTH NETWORK
摘要:Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of Formula (Ia) and (Ib) of IDO, their synthesis, and uses thereof are provided.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:US-6989384-B2
优先权日:2000-06-14
标题:Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis
发明人：HUA YE; LUU HIEP THE; CHAN FORA P; JOHNSON JR THEODORE O; REICH SIEGFRIED HEINZ; SKALITZKY DONALD JAMES; YANG YI; HENDRICKSON THOMAS F; CHU SHAO SONG; EASTMAN BRIAN WALTER
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n nwhere the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.

专利号:US-7122549-B2
优先权日:2000-11-03
标题:Saframycins, analogues and uses thereof
发明人：MYERS ANDREW G; PLOWRIGHT ALLEYN T
权利人:HARVARD COLLEGE
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. n n n n n n n n n n In another aspect, the present invention provides pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. In yet another aspect, the present invention provides methods for treating cancer comprising administering a therapeutically effective amount of a compound of formula (I) to a subject in need thereof.

专利号:US-2024327418-A1
优先权日:2021-08-04
标 题 :Multi-target inhibitor targeting hdac and nad synthesis and use of multi-target inhibitor

专利号:WO-2023011416-A1
优先权日:2021-08-04
标题:Multi-target inhibitor targeting hdac and nad synthesis and use of multi-target inhibitor