CAS: 36404-89-4; 2-Oxo-1,2-Dihydropyridine-3-Carbaldehyde

相似化合物

67383-31-7 71255-09-9 1227603-42-0

上下游产品

CAS号71255-09-9 2-甲氧基-3-吡啶醛 | CAS号114951-38-1 2-hydroxy-3-pyr... | CAS号14265-48-6 β-2',3'-O-isopr... | CAS号114951-44-9 3-pyridine carb... | CAS号114951-35-8 3-pyridinecarba... | CAS号42463-41-2 3-(羟甲基)-1,2-二氢吡啶-2-酮 | CAS号609-71-2 2-羟基烟酸

2-羟基烟酸置于manganese(Iv) Oxide,Lithium Aluminium Tetrahydride,乙酸乙酯体系中,用 四氢呋喃 用作溶剂,化学反应 20.0H,反应生成2-羟基-3-吡啶甲醛
参考文献:Development Of Oxathiino[6,5-B]Pyridine 2,2-Dioxide Derivatives As Selective Inhibitors Of Tumor-Related Carbonic Anhydrases Ix And Xii
标题:Development Of Oxathiino[6,5-B]Pyridine 2,2-Dioxide Derivatives As Selective Inhibitors Of Tumor-Related Carbonic Anhydrases Ix And Xii
摘要:Oxathiino[6,5-B]Pyridine 2,2-Dioxides Are Identified As A New Class Of Isoform-Selective Nanomolar Inhibitors Of Tumor Associated Human Carbonic Anhydrases (Hca) Ix And Xii. At The Same Time They Do Not Inhibit Or Poorly Inhibit Cytosolic Isoforms Hca I And Ii. Oxathiino[6,5-B]Pyridine 2,2-Dioxides Exhibited Good Antiproliferative Properties On Tumor Cell Lines Mcf-7 (Human Breast Adenocarcinoma),A549 (Human Lung (Alveolar) Adenocarcinoma) And Hela (Epithelioid Cervix Carcinoma). (C) 2020 Elsevier Masson Sas. All Rights Reserved.
Doi:10.1016/j.Ejmech.2020.112300

专利信息

专利号:US-7026339-B2
优先权日:2003-11-07
标题 :Inhibitors of HCV NS5B polymerase
发明人：YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
权利人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
摘要:The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.

专利号:US-7256197-B2
优先权日:2001-10-12
标 题 :Methods for synthesis of diarylmethanes
发明人：ROSOWSKY ANDRE; CHEN HAN
权利人:DANA FARBER CANCER INST INC
摘要:The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; methods of preparation of dihydrofolate reductase inhibitors that include metal mediated cross coupling of an aromatic halide or heteroaromatic halide with an organozinc reagent; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.

专利号:US-10759743-B2
优先权日:2016-10-24
标 题 :Pd-catalyzed γ-C(sp3)-H arylation / heteroarylation of free amines
发明人：YU JIN-QUAN
权利人:SCRIPPS RESEARCH INST
摘要:Pd(II)-catalyzed g-G(sp3)-H arylation or heteroarylation of primary amines is realized by using 2-hydroxynicotinaldehyde as a catalytic transient directing group. Importantly, the catalyst and the directing group loading can be lowered to 2% and 4% respectively, thus demonstrating high efficiency of this newly designed transient directing group. Heterocyclic aryl iodides are also compatible with this reaction. Furthermore, swift synthesis of 1,2,3,4-tetrahydronaphthyridine derivatives is accomplished using this reaction.

专利号:US-2004267011-A1
优先权日:2001-10-12
标题:Methods for synthesis of diarylmethanes

专利号:WO-03031458-A1
优先权日:2001-10-12
标题 :Methods for synthesis of diarylmethanes

专利号:CN-117143013-A
优先权日:2023-11-01
标 题 :A kind of synthesis method of 2-chloronicotinic acid