CAS: 3459-92-5; Dibenzyl Carbonate

相似化合物

31139-36-3 140-11-4 39608-52-1

上下游产品

CAS号124-38-9 二氧化碳 | CAS号100-51-6 苯甲醇 | CAS号616-38-6 碳酸二甲酯 | CAS号298-14-6 碳酸氢钾 | CAS号100-44-7 氯化苄 | CAS号480-63-7 2,4,6-三甲基苯甲酸 | CAS号501-53-1 氯甲酸苄酯 | CAS号1001067-06-6 benzyl 3-nitro-... | CAS号534-17-8 碳酸铯 | CAS号100-39-0 溴化苄 | CAS号36443-80-8 1-苄基-3-甲基咪唑氯盐 | CAS号451-40-1 二苯乙酮 | CAS号3333-14-0 2,3-二苯基丙腈 | CAS号103-50-4 二苄醚 | CAS号3333-16-2 2-benzyl-2,3-di... | CAS号120-51-4 苯甲酸苄酯 | CAS号2510-95-4 α-苯基肉桂腈 | CAS号14309-92-3 N-苯甲基-4-硝基苯胺 | CAS号946-80-5 苄基苯基醚 | CAS号46460-73-5 N-(3-氨基丙基)氨基甲酸苄酯

Benzyl 1-Methylimidazole-2-Carboxylate置于三乙烯二胺体系中,用 二氯甲烷,丙酮 作为反应溶剂,化学反应生成 二苄基碳酸盐[脂]
参考文献:Bakhtiar,Cuross; Smith,Edward H.,Journal Of The Chemical Society. Perkin Transactions I,1994,# 3,P. 239-244
标题:Bakhtiar,Cuross; Smith,Edward H.,Journal Of The Chemical Society. Perkin Transactions I,1994,# 3,P. 239-244

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2012165520-A1
优先权日:2010-12-23
标题:Process for the synthesis of prodrugs of opioids
发明人：MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
权利人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
摘要:The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.

专利号:US-9045788-B2
优先权日:2012-07-17
标题:Process for the enzymatic synthesis of (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl) N-methyl methanamine, and application in the synthesis of ivabradine and salts thereof
发明人：PEDRAGOSA-MOREAU SANDRINE; LEFOULON FRANÇOIS; MORIS VARAS FRANCISCO; GONZALEZ SABIN JAVIER
权利人:SERVIER LAB
摘要:Process for the enzymatic synthesis of the compound of formula (I), (7S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)N-methyl methanamine: n nand application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid.

专利号:US-2006287520-A1
优先权日:2005-05-16
标 题 :Synthesis of salinosporamide A and analogues thereof
发明人：DANISHEFSKY SAMUEL J; ENDO ATSUSHI
权利人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
摘要:A novel synthesis of salinosporamide A is provided. Salinospoamide A as well as structurally related natural products, omuralide and lactacystin, have been shown to be proteasome inhibitors. Therefore, these compounds as well as analogues of these natural products may be useful in the treatment of proliferative diseases such as cancer, autoimmune diseases, diabetic retinopathy, etc. The invention provides for the synthesis of salinosporamide A as well as analogs thereof using a convenient point for derivatization of the bicyclic core. Pharmaceutical compositions and method of using the inventive compounds are also provided.

专利号:US-11542269-B2
优先权日:2018-01-03
标 题:Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof
发明人：CHOI HYEONG-WOOK; FANG FRANCIS G
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods utilizing Prins reaction in the preparation of compounds that may be useful as intermediates in the synthesis of halichondrin macrolides and analogs thereof. The invention also provides compounds that may be useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.

专利号:US-7910623-B2
优先权日:2005-07-22
标 题 :Synthesis of scabronines and analogues thereof
发明人：DANISHEFSKY SAMUEL J; WATERS STEPHEN P
权利人:SLOAN KETTERING INST CANCER
摘要:A novel synthesis of scabronines, which are related to a broader class of angularly fused tricyclic diterpenoids known as cyathanes, is provided. Scabronine G, its methyl ester derivative, and other analogs have been shown to have neurotrophic activity. Therefore, these compounds are particularly useful in treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's diseases, etc. The invention provides for the synthesis of scabronines as well as analogs thereof. Pharmaceutical compositions and method of using the inventive compounds are also provided.