CAS: 22412-97-1; Myristyl Laurate

该化合物是源自十二硝酸(光学)酸和丁二甲醇(丙基醇)的脂肪酸酯,该化合物的特点是具有疏水特性,使其在化妆品和工业配方中用作润滑剂,润滑剂或表面活性剂,其长的烷基链有助于稳定性和低挥发性,而其酯联系则确保其与非极质基体的兼容性.该化合物具有中度粘性,并经常被用于个人护理产品中,以取得其皮肤调节效应.其化学结构允许有针对性地溶解和熔化行为,使之适合需要受控释放或阶段稳定性的应用.

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相似化合物

106-18-3 123-95-5 110-36-1

上下游产品

月桂酸 Laurate 143-07-7

合成工艺路线路线简述

    📜甘油三酯,十四醇置于十二烷基苯磺酸体系中,用 水 用作溶剂,化学反应 168.0H,以87%的收率获得十二(烷)酸十四(烷)酯
    参考文献:Dehydration Reactions In Water. Brønsted Acid−surfactant-Combined Catalyst For Ester,Ether,Thioether,And Dithioacetal Formation In Water
    标题:Dehydration Reactions In Water. Brønsted Acid−surfactant-Combined Catalyst For Ester,Ether,Thioether,And Dithioacetal Formation In Water
    摘要:Dehydration Reactions In Water Have Been Realized By A Surfactant-Type Catalyst,Dodecylbenzenesulfonic Acid (Dbsa). These Reactions Include Dehydrative Esterification,Etherification,Thioetherification,And Dithioacetalization. In These Reactions,Dbsa And Substrates Form Emulsion Droplets Whose Interior Is Hydrophobic Enough To Exclude Water Molecules Generated During The Reactions. Detailed Studies On The Esterification Revealed That The Yields Of Esters Were Affected By Temperature,Amounts Of Dbsa Used,And The Substrates. Esters Were Obtained In High Yields For Highly Hydrophobic Substrates. On The Basis Of The Difference In Hydrophobicity Of The Substrates,Unique Selective Esterification And Etherification In Water Were Attained. Furthermore,Chemospecific,Three-Component Reactions Under Dbsa-Catalyzed Conditions Were Also Found To Proceed Smoothly. This Work Not Only May Lead To Environmentally Benign Systems But Also Will Provide A New Aspect Of Organic Chemistry In Water.
    Doi:10.1021/ja026241J

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    专利信息


    专利号:US-7598291-B2
    优先权日:2004-09-02
    标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

    专利号:US-2010160244-A1
    优先权日:2004-09-02
    标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
    发明人:NIMNI MARCEL; HAN BO
    权利人:NIMNI MARCEL; HAN BO
    摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Vladimír Vrkoslav, Et Al. Analysis Of Wax Ester Molecular Species By High Performance Liquid Chromatography/atmospheric Pressure Chemical Ionisation Mass Spectrometry. J Chromatogr A. 2010 Jun 18;1217(25):4184-94.

    合成参考文献


    摘要:International Journal of Toxicology 34(Suppl.2):5-69, 2015
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