CAS: 22352-19-8; (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)-5-(((2R,3R,4S,5R,6R)-3,4,5-Triacetoxy-6-(Acetoxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Tetrahydro-2H-Pyran-2,3,4-Triyl Triacetate

上下游产品

1,2,3,6-tetra-O-acetyl-4-O-trityl-β-D-glucopyranose 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl thi°Cyanate acetic anhydride syringic aldehyde4-nitrophenyl-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-2,3,6-tetra-O-acetyl-β-D-glucopyranoside phenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-acetyl-α-D-glucopyranoside O2,O3,O6-triacetyl-O4-(tetra-O-acetyl-β-D-galactopyranosyl)-α-D-glucopyranoside]phenyl-[O2,O3,O6-triacetyl-O4-(tetra-O-acetyl-β-D-galactopyranosyl)-α-D-glucopyranoside] O2,O3,O6-Triacetyl-O4-(tetra-O-acetyl-β-D-galactopyranosyl)-D-glucoseO2,O3,O6-Triacetyl-O4-(tetra-O-acetyl-β-D-galactopyranosyl)-D-glucose

麦芽糖,乙酸酐置于sodium Acetate体系中,用92%的收率获得β-D-麦芽糖八乙酸酯
参考文献:合成带有带有不同保护基的麦芽糖侧链的三个osw-1类似物.
标题:合成带有带有不同保护基的麦芽糖侧链的三个osw-1类似物.
摘要:为了简化osw-1的二糖侧链的合成并探索osw-1的结构-活性关系,设计并合成了三个带有三个具有不同保护基的麦芽糖侧链的16α-O-麦芽糖osw-1类似物.
Doi:10.1080/10286020.2013.863185

专利信息

专利号:US-5530107-A
优先权日:1992-10-15
标 题:Method for making steroidal peracyl glycosides
发明人：ALLAN DOUGLAS J M; BUSCH FRANK R; LAMBERT JOHN F; SHINE RUSSELL J; WALINSKY STANLEY W
权利人:PFIZER
摘要:Processes for the synthesis of tigogenin beta-O-cellobioside heptaalkanoate which is an intermediate for the known hypocholesterolemic agent tigogenin beta-cellobioside. The process comprises reacting α-cellobiosyl bromide heptaalkanoate and β-tigogenin in the presence of zinc fluoride or zinc cyanide under conditions capable of forming said tigogenyl β-O-cellobioside heptaalkanoate. The analogous preparations of hecogenin β-O-cellobioside heptaalkanoate, 11-ketotigogenin β-O-cellobioside heptaalkanoate, and diosgenin β-O-cellobioside heptaalkanoate are also disclosed. The process provides both high β-anomeric selectivity and high yields.

专利号:US-5010185-A
优先权日:1989-06-13
标 题:Processes for tigogenin beta-cellobioside
发明人：URBAN FRANK J
权利人:PFIZER
摘要:Improved processes for the synthesis of tigogenin beta-cellobioside, a known hypocholesterolemic agent, using cellobiose heptaacetate and tigogenin as starting materials.