CAS: 203245-17-4; 1,2,3-Trifluoro-5-Methoxybenzene
该化合物是一种芳香化合物,其特点是存在三个氟原子和一个附于苯环的甲氧(-OCH3)组,三氟甲基组对其化学特性有重大影响,提高了其电子密度,使其与非氟类比相比更具反应性.由于苯环的芳香性质,这种化合物一般具有高度稳定性,而氟代成分可产生独特的溶性特征,并改变其与生物系统的互动.甲基氧组有助于其总体极度,并可能影响其在电子代用芳香反应中的再活动. 1,3-三氟-5-氟氧苯因其独特性质,可在各个领域找到应用,包括药品,农业化学品和材料科学.应当参考安全数据,以便处理和使用,因为氟化化合物可构成特定的健康和环境风险.
- 英文名称1,2,3-Trifluoro-5-Methoxybenzene
- 中文名称3,4,5-三氟苯甲醚
- IUPAC名称1,2,3-trifluoro-5-methoxybenzene
- 其它别名1,2,3-三氟-5-甲氧基苯; Benzene, 1,2,3-Trifluoro-5-Methoxy- (9Ci)
- CAS编号203245-17-4
- MFCD编号:MFCD00042397
- EINECS号:670-637-2
- 分子式:C7H5F3O分子量:162.11
- 产品CID: 1031790
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
海关参考信息
- 2905110000-甲醇
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7615634-B2
优先权日:2003-02-10
标题:4-aminopyrimidine-5-one derivatives
发明人：BARTKOVITZ DAVID JOSEPH; CHU XIN-JIE; DING QINGJIE; JIANG NAN; LOVEY ALLEN JOHN; MOLITERNI JOHN ANTHONY; MULLIN JR JOHN GUILFOYLE; VU BINH THANH; WOVKULICH PETER MICHAEL
权利人:HOFFMANN LA ROCHE
摘要:Novel intermediate compounds are disclosed. These compounds are useful in the synthesis of 4-aminopyrimidine-5-one derivatives that inhibit cyclin-dependent kinases, in particular cyclin-dependent kinase 4 (Cdk4). The 4-aminopyrimidine-5-one derivatives and their pharmaceutically acceptable salts have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors.
专利号:CA-3170288-A1
优先权日:2020-03-04
标题:Synthesis of novel ep4 antagonist and use in cancer and inflammation
专利号:EP-4116291-A1
优先权日:2020-03-04
标题:Synthesis of novel ep4 antagonist and use in cancers and inflammations
专利号:US-2023125494-A1
优先权日:2020-03-04
标题 :Synthesis of novel ep4 antagonist and use in cancer and inflammation
专利号:CN-113354585-A
优先权日:2020-03-04
标 题:Synthesis of novel EP4 antagonists and their use in cancer and inflammation
