CAS: 17348-76-4; 2'-Hydroxyflavanone

该化合物是一种自然产生的花草衍生物, 具有强健的抗氧化剂和抗炎特性. 它在水溶液中表现出极好的溶解性, 适合食品和制药工业的各种应用. 这个化合物因其在调节生物过程方面的潜力而特别受重视, 为研究人员和开发者提供了一个多功能的选择.

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上下游产品

trans-2,2'-dihydroxychalcone 2-methyl-benzyl alcohol o-hydroxyacetophenone 2-(methoxymethoxy)benzaldehyde 2-(4-ox°Chroman-2-yl)phenyl phenylcarbamate 2-[3-(2-hydroxyphenyl)propyl]phenol 4-[1,3-Bis-(2-hydroxy-phenyl)-propyl]-2-[3-(2-hydroxy-phenyl)-propyl]-phenol

合成工艺路线路线简述

    📜3-苯氧基丙腈置于2,2'-联吡啶,Palladium(II) Trifluoroacetate,三氟甲磺酸,氧气,三氟乙酸体系中,用 1,4-二氧六环,二甲基亚砜 用作溶剂,化学反应 16.0H,反应生成2-羟基黄烷酮
    参考文献:通过钯(II)催化色胺酮与芳基硼酸的一锅β-芳基化反应合成黄酮.
    标题:通过钯(II)催化色胺酮与芳基硼酸的一锅β-芳基化反应合成黄酮.
    摘要:合宜地通过一锅二价的苯并二氢吡喃酮与芳基硼酸通过串联钯(II)催化合成了苯并二氢吡喃酮(一类具有化学未活化β位点的简单酮),合成了47种黄烷酮.该反应提供了一种以高达92%的收率获得各种黄烷酮(包括天然产物,如柚皮苷三甲醚)的新颖途径.
    Doi:10.1021/acs.Joc.9B01162

    海关参考信息

    专利信息


    专利号:US-2019314312-A1
    优先权日:2016-07-11
    标题 :Combination therapy to increase endogenous nitric oxide (no) synthesis
    发明人:EREZ AYELET; STETTNER NOA
    权利人:YEDA RES & DEV
    摘要:Provided are uses of a therapeutically effective amount of citrulline for the manufacture of a medicament for treatment of a subject having an inflammatory bowel disease (IBD) and/or colon cancer. Also provided are pharmaceutical compositions comprising a therapeutic effective amount of citrulline and a therapeutically effective amount of a flavonoid for the treatment of an inflammatory bowel disease (IBD) and/or colon cancer and kits comprising same.

    专利号:US-2013164265-A1
    优先权日:2011-12-21
    标题 :Skin care compositions
    发明人:FLAVIN DANA; OBENLAND SIGRID
    权利人:FLAVIN DANA; OBENLAND SIGRID
    摘要:This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

    专利号:US-2014328952-A1
    优先权日:2011-12-21
    标题:Topical compositions
    发明人:FLAVIN DANA
    权利人:FLAVIN DANA
    摘要:This invention provides compositions and methods of manufacturing such compositions that employ GRAS compounds which can act to promote the generation of stem, epidermal or other skin cells in the epidermis, activation of collagen synthesis, activation of hyaluronic acid synthesis, enhanced skin hydration, and dermal healing by stimulating stem cell and fibroblast migration to sites of needed repair. These compositions and methods are useful for rejuvenating the skin and for treating some skin-related aging or other dermal damaging conditions, including wrinkle reduction and treatment of minor dermal wounds.

    专利号:US-8790720-B2
    优先权日:2011-12-22
    标题:Compositions and methods for treating skin
    发明人:RICHARDS JEANETTE ANTHEA; DAWSON THOMAS LARRY; COMBS MARY JANE; DUEVA-KOGANOV OLGA; KOGANOV MICHAEL
    权利人:PROCTER & GAMBLE
    摘要:The present invention relates to skin care compositions comprising blends of camellia and feverfew serum fractions and/or kelp and parsley serum fractions. The skin care compositions also comprise a dermatologically acceptable carrier. The invention also relates to methods for increasing melanin production in skin by topically applying the skin care composition to areas in order to stimulate one or more steps in melanin synthesis and/or interrupt an inflammatory cycle.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/j.tiv.2020.104966
    摘要:Sonowal H, Ramana KV. 2′-Hydroxyflavanone prevents LPS-induced inflammatory response and cytotoxicity in murine macrophages. Toxicology in Vitro. 2020 Dec;69():104966. doi: 10.1016/j.tiv.2020.104966.
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