相似化合物
14866-33-2 4368-51-8 4328-13-6欧盟法规
ECHA物质C&L通报REACH预注册Tetradecylammonium Iodide 反应生成四癸基溴化铵
参考文献:Raxmanko,E. M.;Egorov,V. V.;Tsvirko,G. A.;Koleshko,L. V.;Sloboda,N. +,Sostoyanie I Perspektivy Razvitiya Assortimenta Xim. Reaktivov Dlya Vazhn+
标题:Raxmanko,E. M.;Egorov,V. V.;Tsvirko,G. A.;Koleshko,L. V.;Sloboda,N. +,Sostoyanie I Perspektivy Razvitiya Assortimenta Xim. Reaktivov Dlya Vazhn+
专利信息
专利号:US-6695969-B1
优先权日:1998-09-18
标 题 :Process for obtaining HMG-CoA reductase inhibitors of high purity
发明人:GRAHEK ROK; MILIVOJEVIC DUSAN; BASTARDA ANDREJ
权利人:LEK PHARMACEUTICALS
摘要:Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as and antihypercholesterolemic agents. The majority of them are produced by fermentation using microorganisms of different species identified as species belonging to Aspergilus, Monascus, Nocardia, Amycolatopsis, Mucor or Penicilium genus, some are obtained by treating the fermentation products using the method of chemical synthesis or they are the products of total chemical synthesis. The purity of the active ingredient is an important factor for manufacturing the safe and effective pharmaceutical, especially if the pharmaceutical product must be taken on a longer term basis in the treatment or prevention of high plasma cholesterol. The accumulation of the impurities from the pharmaceuticals of lower purity may cause many side effects during the medical treatment. The present invention relates to a new industrial process for the isolation of HMG-CoA reductase inhibitors using so-called displacement chromatography. Use of the invention enables to obtain HMG-CoA reductase inhibitors of high purity, with high yields, lower production costs and suitable ecological balance.
专利号:US-7141602-B2
优先权日:1998-09-18
标题:Process for obtaining HMG-CoA reductase inhibitors of high purity
发明人:GRAHEK ROK; MILIVOJEVIC DUSAN; BASTARDA ANDREJ
权利人:LEK PHARMACEUTICALS
摘要:Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The majority of them are produced by fermentation using microorganisms of different species identified as species belonging to Aspergillus, Monascus, Nocardia, Amycolatopsis, Mucor or Penicillium genus, Streptomyces, Actinomadura, Micromonospora , some are obtained by treating the fermentation products using the method of chemical synthesis or they are the products of total chemical synthesis. The purity of the active ingredient is an important factor for manufacturing the safe and effective pharmaceutical, especially if the pharmaceutical product must be taken on a longer term basis in the treatment or prevention of high plasma cholesterol. The accumulation of the impurities from the pharmaceuticals of lower purity may cause many side effects during the medical treatment. The present invention relates to a new industrial process for the isolation of HMG-CoA reductase inhibitors using so-called displacement chromatography. Use of the invention enables one to obtain HMG-CoA reductase inhibitors of high purity, with high yields, lower production costs and suitable ecological balance.
专利号:US-2008214386-A1
优先权日:2004-03-01
标题:Catalyst for Cyclic Carbonate Synthesis
发明人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU
权利人:TAKAHASHI TOSHIKAZU; WATAHIKI TSUTOMU; YASUDA HIROYUKI; SAKAKURA TOSHIYASU
摘要:Provided are a solid catalyst which gives a cyclic carbonate at a high yield and a high selectivity, which is stable and which may be readily separated after reaction; and a method of industrially advantageous, inexpensive and safe production of a cyclic carbonate by the use of the catalyst. The catalyst contains an inorganic solid substance having a surface modified with an ionic substance containing a Group 15 element; or contains an ionic substance containing a Group 15 element, and an inorganic solid substance. The modifying group for surface modification of an inorganic solid substance is an ionic substance containing a Group 15 element. The ionic substance containing a Group 15 element is at least one substance selected from organic phosphonium salts, organic ammonium salts, organic arsonium salts and organic antimonium salts.
专利号:US-10442696-B2
优先权日:2014-05-06
标 题 :Shape-controlled cement hydrate synthesis and self-assembly
发明人:SHAHSAVARI ROUZBEH; EBRAHIMPOURMOGHADDAM SAKINEH; WHITMIRE KENTON HERBERT
权利人:UNIV RICE WILLIAM M
摘要:In some embodiments, the present disclosure pertains to methods of forming calcium-silicate-hydrate particles by mixing a calcium source with a silicate source. In some embodiments, the mixing comprises sonication. In some embodiments, the mixing occurs in the presence of a surfactant and a solvent. In some embodiments, the methods of the present disclosure further comprise a step of controlling the morphology of the calcium-silicate-hydrate particles. In some embodiments, the step of controlling the morphology of calcium-silicate-hydrate particles comprises selecting a stoichiometric ratio of the calcium source over the silicate source. In some embodiments, the formed calcium-silicate-hydrate particles have cubic shapes. In some embodiments, the formed calcium-silicate-hydrate particles have rectangular shapes. In some embodiments, the formed calcium-silicate-hydrate particles are in the form of self-assembled particles of controlled shapes. Additional embodiments of the present disclosure pertain to compositions that contain the calcium silicate-hydrate particles of the present disclosure.
专利号:US-12344944-B2
优先权日:2019-06-24
标题 :Method for HF-free facile and rapid synthesis of MXenes related compounds
发明人:HAO JIANHUA; PANG SIN YI
权利人:UNIV HONG KONG POLYTECHNIC
摘要:Provided herein is a method for preparing MXenes, such as Ti2CTx, Cr2CTx, and V2CTx, products prepared therefrom, and compositions and devices including the same.
专利号:US-2020399771-A1
优先权日:2019-06-24
标 题:Method for hf-free facile and rapid synthesis of mxenes related compounds