CAS: 10138-93-9; Triethylamine Phosphate(1:X)

📜三乙胺置于磷酸体系中,用 水,乙腈 用作溶剂,化学反应生成磷酸-三乙胺 2:1
参考文献:隐孢子虫中非手性(z)-γ-双萜的生物合成的立体化学研究
标题:隐孢子虫中非手性(z)-γ-双萜的生物合成的立体化学研究
摘要:一种新近鉴定的细菌(z)-γ-双萜烯合酶被用于研究倍半萜烯的环化机理.由于非手性产物形成过程中手性推定中间体神经节苷酸二磷酸酯(npp)和双双烯丙基阳离子的立体信息丢失,因此通过将npp的两个对映异构体与重组酶一起孵育解决了其绝对构型的有趣问题.在(R)-Npp的唯一环化中,对(z)-γ-双糖单烯合酶非天然的(S)-Npp被特异地转化为(e)-β-法呢烯.提出了解释这些发现的假设酶机制模型.
Doi:10.3762/bjoc.15.75

专利信息

专利号:US-7241399-B2
优先权日:2000-09-08
标题 :Synthesis of nanoparticles
发明人：HAUBOLD STEPHAN; HAASE MARKUS; RIWOTZKI KARSTEN; WELLER HORST; MEYSSAMY HEIKE; IBARRA FERNANDO
权利人:CT ANGEWANDTE NANOTECH CAN
摘要:Methods for the preparation of inorganic nanoparticles capable of fluorescence, wherein the nanoparticles consist of a host material that comprises at least one dopant. The synthesis of the invention in organic solvents allows to gain a considerably higher yield compared to the prior art synthesis in water. All kinds of objects can advantageously be marked and reliably authenticated by using an automated method on the basis of a characteristic emission. Further, the size distribution of the prepared nanoparticles is nartower which renders a subsequent size-selected separation process superfluous.

专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人：NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:EP-0443532-B1
优先权日:1990-02-20
标题:Temporary minimal protection synthesis of LH-RH analogs
发明人：NESTOR JOHN J JR; MCCLURE NATALIE L
权利人:SYNTEX INC
摘要:A solid phase synthesis of LH-RH analogs in which the amino acids serine and histidine, if present, are side chain protected during the synthesis with groups labile to selected alpha -amino or deprotecting agents.

专利号:US-2007066835-A1
优先权日:2003-03-24
标 题:Process for the synthesis of amorphous atorvastain calcium
发明人：CZIBULA LASZLO; DOBAY LASZLO; PAPP EVA W; JUHASZ IDA D; BALINT SANDORNE
权利人:CZIBULA LASZLO; DOBAY LASZLO; PAPP EVA W; JUHASZ IDA D; BALINT SANDORNE
摘要:The invention relates to a new process for the synthesis of amorphous atorvastatin calcium, which consists of dissolving the salt of the formula (I) of atorvastatin acid formed with a basic amino acid (I); in a mixture of water and a water miscible organic solvent, adding an aqueous solution of a water soluble calcium salt to the solution and isolating the so obtained entirely amorphous atorvastatin calcium of high purity by filtration.

专利号:EP-1960423-B1
优先权日:2004-12-30
标 题:Synthesis of peptide t-20 using peptide intermediate fragments
发明人：HAN YEUN-KWEI; JOHNSTON DAVID A; KHATRI HIRALAL N
权利人:HOFFMANN LA ROCHE
摘要:Methods for the solid phase synthesis of T-20 peptides and peptide intermediates, in particular methods involving synthesizing T-20 peptide intermediates at low loading factors to produce products having excellent purity and yield.

专利号:EP-1232226-B1
优先权日:2000-09-08
标题:Synthesis of nanoparticles
发明人：HAUBOLD STEPHAN; HAASE MARKUS; RIWOTZKY CARSTEN; WELLER HORST; MEYSAMMY HEIKE; IBARRA FERNANDO
权利人:NANOSOLUTIONS GMBH
摘要:Production of inorganic nanoparticles that can be fluoresced consisting of a host material containing a dopant comprises using an organic solvent for liquid phase synthesis of the particles.