CAS: 100114-24-7; 5-Methyl-2-(Methylthio)Pyrimidine

该化合物是七环有机化合物,在5点和2点以一甲基组替代一个火水晶体核心,在5点和甲基硫基组中,这种结构具有独特的反应性,使其成为制药和农用化学合成中有价值的中间体.含有硫的功能组在核糖代谢反应中增强了多功能性,而甲基替代则影响电子特性,用于量身定制应用.该化合物在标准条件下表现出稳定性,确保可靠的处理和储存.其明确界定的分子框架有利于构建复杂的七环系统,特别是在生物活性分子的开发中.它适合于研究和工业用途,它符合合成应用的高纯度标准.

结构式图片

相似化合物

38275-43-3 90905-31-0 19858-50-5

上下游产品

CAS号84755-30-6 4-甲基-2-(甲硫基)嘧啶-5-甲醛

合成工艺路线路线简述

    专利信息


    专利号:WO-2024137329-A1
    优先权日:2022-12-20
    标 题:Methods for the synthesis of complement factor d inhibitors and intermediates thereof
    发明人:HASHIMOTO AKIHIRO; TIPPARAJU SURESH KUMAR
    权利人:ALEXION PHARMA INC
    摘要:The present disclosure provides methods for the synthesis of complement factor D inhibitors and intermediates thereof.

    专利号:US-8772301-B2
    优先权日:2009-12-18
    标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
    发明人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
    权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
    摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

    专利号:WO-2023114200-A2
    优先权日:2021-12-14
    标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof

    专利号:WO-2023114198-A2
    优先权日:2021-12-15
    标题 :Methods for the synthesis of complement factor d inhibitors

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 190.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知