1-乙基-1-甲基-环丙烷置于nickel Kieselguhr体系中,250.0 °C,17.65 Mpa 条件下,反应生成 2,2-二甲基丁烷 参考文献:Derfer; Greenlee; Boord,Journal Of The American Chemical Society,1949,Vol. 71,P. 180 标题:Derfer; Greenlee; Boord,Journal Of The American Chemical Society,1949,Vol. 71,P. 180
专利号:US-11926589-B2 优先权日:2019-07-09 标 题 :Process for the synthesis of non-racemic cyclohexenes 发明人:REISMAN SARAH; ROMBOLA MICHAEL; LADD CAROLYN L; MCLAUGHLIN MARTIN JOHN; ZUEND STEPHAN; GOETZ ROLAND 权利人:BASF CORP; CALIFORNIA INST OF TECHN 摘要:This invention relates to a process for the synthesis of a non-racemic cyclohexene compound of formula (I) by a Diels-Alder reaction of a compound of formula (II) with a compound of formula (III) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and Y have the meanings as defined in the description in the presence of a catalyst comprising at least one m-valent metal cation M m+ wherein the metal M is selected from Scandium (Sc), Yttrium (Y), Lanthanum (La), Cerium (Ce), Praseodymium (Pr), Neodymium (Nd), Promethium (Pm), Samarium (Sm), Europium (Eu), Gadolinium 15 (Gd), Terbium (Tb), Dysprosium (Dy), Holmium (Ho), Erbium (Er), Thulium (Tm), Ytterbium (Yb), Lutetium (Lu), Gallium (Ga) and Indium (In), and m is an integer of 1, 2 or 3, and a chiral ligand of the formula (IV) wherein R 10a , R 10b , R 10c , R 10d , R 10a′ , R 10b′ , R 10c′ , R 10d′ , Z and Z′ have the meanings as defined in the description.
专利号:US-2021107859-A1 优先权日:2018-04-06 标题 :A process for the synthesis of carbon labeled organic compounds 发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA 权利人:COMMISSARIAT ENERGIE ATOMIQUE 摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.
专利号:US-7973171-B2 优先权日:2005-06-13 标题:Process for synthesis of dialkoxyorganoboranes 发明人:BURKHARDT ELIZABETH; ATKINS WILLIAM 权利人:BURKHARDT ELIZABETH; ATKINS WILLIAM 摘要:The invention relates to a process for the synthesis of dialkoxyorganoboranes, in particular to a process for the synthesis of dialkoxyorganoboranes by an ester exchange reaction. Moreover, the invention relates to a process for the synthesis of organo-oxazaborolidine catalysts (organo-CBS) and of trialkylboroxins. Furthermore, the invention relates to methods of using dialkoxyorganoboranes for the preparation of organo-CBS catalysts and in Suzuki-type coupling reactions.
专利号:US-10711138-B2 优先权日:2016-04-08 标题:Intermediates and procedures for the synthesis of functional materials 发明人:KIRSCH PEER; GUNST SUSANN 权利人:MERCK PATENT GMBH 摘要:The present invention relates to heteroaromatic compounds which have two different reactive groups, their use in the synthesis of asymmetrically substituted compounds, and synthesis processes in which the compounds according to the invention are reacted sequentially with two different compounds, whereby an asymmetrically substituted compound is formed.
专利号:US-2024228455-A1 优先权日:2021-04-27 标 题 :Synthesis of cbn and cbnv 发明人:KAVARANA MALCOLM J 权利人:TEEWINOT LIFE SCIENCES CORP 摘要:The invention includes chemical synthesis for preparing cannabinol (CBN) and cannabinovarin (CBNV). The process is suitable for inter alia the large-scale synthesis of pharmaceutical grade CBN and CBNV.
专利号:US-8569560-B2 优先权日:2006-10-13 标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis 发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J 权利人:ELEVANCE RENEWABLE SCIENCES 摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.
摘要:Molnár, Á.; Margaretha, P., Science of Synthesis, (2009) 48, 465. 摘要:Zaidlewicz, M.; Krzemiński, M. P.; Dzieleńdziak, A., Science of Synthesis, (2009) 48, 373. 摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 550. 摘要:de Meijere, A.; Kozhushkov, S. I., Science of Synthesis, (2009) 48, 504. 摘要:Eilbracht, P., Science of Synthesis, (2009) 48, 414.