间氟苯甲醚 反应生成 2-氟-4-甲氧基苯乙酮 参考文献:Method Of Treating Diabetes And Related Disease States 标题:Method Of Treating Diabetes And Related Disease States 摘要:本发明涉及乙酰苯酚,其作为抗肥胖和抗糖尿病化合物有用.本发明还公开了使用该化合物治疗糖尿病和肥胖症,降低或调节甘油三酯水平和胆固醇水平或提高高密度脂蛋白水平或增加肠道动力或治疗动脉硬化的组合物和方法.
专利号:WO-2013091696-A1 优先权日:2011-12-21 标题 :Synthesis of intermediates for preparing anacetrapib and derivatives thereof 发明人:HUMLJAN JAN; MARAS NENAD 权利人:LEK PHARMACEUTICALS; HUMLJAN JAN; MARAS NENAD 摘要:The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
专利号:EP-2468735-A1 优先权日:2010-12-23 标 题:Synthesis of intermediates for preparing anacetrapib and derivates thereof 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
专利号:US-9212118-B2 优先权日:2010-12-23 标题:Synthesis of intermediates for preparing anacetrapib and derivatives thereof 发明人:HUMLJAN JAN; MARAS NENAD 权利人:HUMLJAN JAN; MARAS NENAD; LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
专利号:US-5877296-A 优先权日:1994-06-03 标题:Process for preparing conjugates of methyltrithio antitumor agents 发明人:HAMANN PHILIP ROSS; HINMAN LOIS; HOLLANDER IRWIN 权利人:AMERICAN CYANAMID CO 摘要:This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.
专利号:US-5739116-A 优先权日:1994-06-03 标题:Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents
专利号:CN-103384663-B 优先权日:2010-12-23 标题:Synthesis of intermediates for the preparation of anacetrapib and derivatives thereof
参考标题: Synthesis Of Intermediates For Preparing Anacetrapib And Derivatives Thereof Synthèse D'Intermédiaires Pour Préparer L'Anacétrapib Et Ses Dérivés 摘要:The Present Invention Relates To The Field Of Organic Chemistry, More Specifically To The Synthesis Of Intermediate Compounds Which Can Be Used In The Synthesis Of Pharmaceutically Active Agents Such As Anacetrapib Or Derivatives Thereof.
合成参考文献
参考文献:10.1007/s11664-025-12060-w 摘要:Jamaludin SHW, Baharudin NAS, Abdullah NS, Mahussin NW, Yushaizad NS, Razak IA, Zainuri DA. Revealing the Connection Between Electronic Structure and Nonlinear Optical Performance in Anthracene Chalcones. J. Electron. Mater. 2025 Jun 09;54(8):6715–27. doi: 10.1007/s11664-025-12060-w.