CAS: 27314-13-2; Norflurazon

该化合物是一种选择性除草剂,主要用于控制各种作物中的年草和某些大叶杂草,属于微米津酮化学类,其功能是抑制对植物开发和光合作用至关重要的类动物生物合成,对植物发育和光合作用至关重要;这种抑制导致植物组织脱色,最终导致植物死亡;诺氟布拉松的特点是水溶性相对较低,这助长了其在土壤中的持久性和杂草管理的有效性;它通常是在长发之前针对杂草使用前的预发性;该化合物对哺乳动物具有中度的毒性,但必须小心处理,以尽量减少环境影响;它的应用在许多区域受到管制,以确保安全使用和保护非目标生物;

结构式图片

相似化合物

1698-60-8 23576-24-1 37627-05-7

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

methylamine 4,5-dichloro-2-(3-trifluoromethylphenyl)-pyridazine-3(2H)-one

合成工艺路线路线简述

  • 合成目标产物 Norflurazon 主要起始原料 Methylamine And 4,5-Dichloro-2-[3-(Trifluoromethyl)Phenyl]Pyridazin-3(2H)-One
  • (文献来源)合成步骤主要原料 Methylamine 和 4,5-Dichloro-2-[3-(Trifluoromethyl)Phenyl]Pyridazin-3(2H)-One
📜甲胺,4,5-二氯-2-(3-三氟甲基苯基)-3(2H)哒嗪酮 以 甲苯 用作溶剂,化学反应 7.0H,以27%的收率获得5-Chloro-4-Methylamino-2-(3-Trifluoromethyl-Phenyl)-2H-Pyridazin-3-One
参考文献:Konecny,Vaclav; Kovac,Stefan; Varkonda,Stefan,Collection Of Czechoslovak Chemical Communications,1985,Vol. 50,# 2,P. 492-502
标题:Konecny,Vaclav; Kovac,Stefan; Varkonda,Stefan,Collection Of Czechoslovak Chemical Communications,1985,Vol. 50,# 2,P. 492-502

海关参考信息

专利信息


专利号:US-2015239796-A1
优先权日:2014-02-19
标题:One pot synthesis of 18f labeledtrifluoromethylated compounds with difluoro(iodo)methane
发明人:RüHL THOMAS; RISS PATRICK; RAFIQUE WAQAS
权利人:UNIV OSLO
摘要:The present invention relates to compositions and methods for the synthesis of 18 F labeled compounds. In particular, the present invention relates to a copper (I) mediated one pot method for 18 F-trifluoromethylation of aromatic- or heteroaromatic halides with difluoro(iodo)methane (e.g., for use at PET imaging agents).

专利号:US-11919928-B2
优先权日:2016-03-16
标题 :Method for producing dihydrotentoxin
发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:KUMIAI CHEMICAL INDUSTRY CO
摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

专利号:US-5877186-A
优先权日:1997-04-28
标题 :Carotenoid synthesis inhibiting herbicides and fatty acid synthesis inhibiting oxime herbicides as anti-apicomplexa protozoan parasite agents
发明人:LEEF JAMES L; CARLSON PETER S
权利人:PARAPRO LLC
摘要:Protozoan parasites of the phylum Apicomplexa include some of the most important causative agents of human and animal diseases, in particular, malaria. The discovery that an organelle found inside parasites of this phylum probably stems from a plastid of plant origin has stimulated research on the effect of chemical herbicidal agents on Apicomplexa. Members of the triazine family and of the dinitroaniline family of herbicides have been found to be active against some Apicomplexa. The present invention extends the list of chemical herbicidal agents active against Apicomplexa to include classes of herbicides active as carotenoid synthesis inhibitory agents in plants and herbicidal agents effective against fatty acid synthesis in plants.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人:KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

专利号:ES-2717283-T3
优先权日:2012-07-24
标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献


1: Sathishkumar P, Mangalaraja RV, Rozas O, Vergara C, Mansilla HD, Gracia-Pinilla MA, Anandan S. Sonophotocatalytic mineralization of Norflurazon in aqueous environment. Chemosphere. 2016 Mar;146:216-25. doi: 10.1016/j.chemosphere.2015.12.011. Epub 2015 Dec 28. doi: 10.1371/journal.pone.0099894. eCollection 2014.
3: Wilson PC, Koch R. Influence of exposure concentration and duration on effects and recovery of Lemna minor exposed to the herbicide norflurazon. Arch Environ Contam Toxicol. 2013 Feb;64(2):228-34. doi: 10.1007/s00244-012-9834-8. Epub 2012 Dec 1. doi: 10.1007/s00253-014-5593-y. Epub 2014 Mar 4. doi: 10.1093/mp/sst020. Epub 2013 Feb 1.
6: Saini G, Meskauskiene R, Pijacka W, Roszak P, Sjögren LL, Clarke AK, Straus M, Apel K. 'happy on norflurazon' (hon) mutations implicate perturbance of plastid homeostasis with activating stress acclimatization and changing nuclear gene expression in norflurazon-treated seedlings. Plant J. 2011 Mar;65(5):690-702. doi: 10.1111/j.1365-313X.2010.04454.x. Epub 2011 Jan 5. doi: 10.1007/s00128-011-0380-2. Epub 2011 Aug 11. doi: 10.1021/jf902525n. doi: 10.1016/j.jhazmat.2011.08.039. Epub 2011 Aug 31. doi: 10.1016/j.scitotenv.2012.08.022. Epub 2012 Oct 5. doi: 10.1093/pcp/pcr069. Epub 2011 Jun 1. Epub 2007 Apr 4.

合成参考文献


参考文献:10.3390/md9061101
摘要:Takaichi S. Carotenoids in algae: distributions, biosyntheses and functions. Mar Drugs. 2011;9(6):1101–18.
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