专利号:WO-9617589-A1 优先权日:1994-12-08 标 题 :Method of smoothing or removing wrinkles and method of stimulating collagen synthesis 发明人:FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO 权利人:KAO CORP; FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO 摘要:The present invention relates to methods of stimulating collagen synthesis and of smoothing or removing wrinkles, which comprise administering an effective amount of a benzoic acid derivative of formula (1) or a salt thereof, wherein X is -O- or -N(R4)- (R4 is H or the like), R1 is a C¿4-25?-alkyl or C4-25-alkenyl group, R?2¿ is H, OH, or a C¿1-6?-alkoxyl or C1-6-alkanoyloxy group, and R?3 is -OR5¿ or -N(R?6)R7 (R5? is H, or a C1-25-alkyl or C1-25-alkenyl group), and R?6 and R7¿ are individually H, or a C¿1-3?-alkyl or C1-3-alkenyl group, and use of this compound for agents for stimulating synthesis of collagen, and smoothing or removing wrinkles. This compound (1) stimulates collagen synthesis in human dermal fibroblasts and consequently smooths or removes wrinkles caused by aging and/or photoaging.
专利号:US-9136483-B1 优先权日:2014-04-17 标 题:Thiophene fused azacoronenes: regioselective synthesis, self organization, charge transport, and its incorporation in conjugated polymers 发明人:LIU YI; HE BO 权利人:LIU YI; HE BO; UNIV CALIFORNIA 摘要:A regioselective synthesis of an azacoronene fused with two peripheral thiophene groups has been realized through a concise synthetic route. The resulting thienoazacoronene (TAC) derivatives show high degree of self-organization in solution, in single crystals, in the bulk, and in spuncast thin films. Spuncast thin film field-effect transistors of the TACs exhibited mobilities up to 0.028 cm 2 V −1 S −1 , which is among the top field effect mobilities for solution processed discotic materials. Organic photovoltaic devices using TAC-containing conjugated polymers as the donor material exhibited a high open-circuit voltage of 0.89 V, which was ascribable to TAC's low-lying highest occupied molecular orbital energy level.
专利号:US-2008021209-A1 优先权日:2006-06-01 标题:Ethers of bisanhydrohexitols 发明人:EAST ANTHONY; JAFFE MICHAEL; ZHANG YI; CATALANI LUIZ H 权利人:NEW JERSEY TECH INST 摘要:A novel method for the synthesis of ethers of anhydrosugars, such as isosorbide, isomannide, and isoidide, is disclosed. The bisglycidyl ethers are useful as substitutes for bisphenol A in the manufacture of thermoset epoxy ethers. Anhydrosugar ethers are derived from renewable sources and are not xenoestrogenic. Higher alkyl and aralkyl ethers are stable high-boiling oils that are good plasticizers for materials such as PVC.
专利号:US-9777034-B2 优先权日:2013-05-21 标题 :Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes 发明人:PERCEC VIRGIL 权利人:UNIV PENNSYLVANIA 摘要:The invention concerns compounds of the formula (I) wherein: Y 1 and Y 2 are independently a monosaccharide or disaccharide; X 1 and X 2 are independently —(R 9 —O) m —, —(R 10 ) p —, —O—(R 11 —O) q —, —R 16 —O—R 17 —O— or a covalent bond; Q 1 and Q 2 are independently a nitrogen-containing heterocycle moiety; Z 1 and Z 2 are independently —(O—R 7 )—, —(O—C(â•?O)—R 8 )a-, —O—C(â•?O)—R 12 —C(=0)-R 13 —, —O—C(â•?O)—R 14 —C(â•?O)—R 15 or a covalent bond; R 7 -R 17 are each independently C 1 -C 6 alkyl; R 1 -R 6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.
专利号:US-7799932-B2 优先权日:2005-10-06 标 题:N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles 发明人:REYNOLDS JOHN R; WALCZAK RYAN M; COWART II JOHN SIGURE 权利人:UNIV FLORIDA 摘要:A family of N-substituted 3,4-alkylenedioxypyrrole includes monomers for of formula (I) electropolymerization to conjugated polymers and key intermediates for the preparation of the monomers. The preparation of the //-substituted 3,4-alkylenedioxypyrroles is carried out via a synthetic intermediate, an ester substituted dihydroxypyrrole. The synthetic method to prepare the //-substituted 3,4-alkylenedioxypyrrole intermediates and ultimately the N-substituted 3,4-alkylenedioxypyrrole monomers begins with a reaction to form the ester substituted dihydroxypyrrole.
专利号:US-2009149661-A1 优先权日:2005-10-06 标题 :N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles
[参考文献]: Lijun Huo, Et Al. Synthesis Of A 4,8-Dialkoxy-Benzo[1,2-B:4,5-B']Difuran Unit And Its Application In Photovoltaic Polymer. Chem Commun (Camb). 2012 Apr 4;48(27):3318-20.
合成参考文献
摘要:Braun, M., Science of Synthesis Knowledge Updates, (2017) 1, 452.