专利号:US-2004110228-A1 优先权日:2002-04-01 标 题:Combinatorial organic synthesis of unique biologically active compounds 发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M 摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.
专利号:US-2017246690-A1 优先权日:2014-06-20 标 题:Stabilizing agent-free metal nanoparticle synthesis and uses of metal nanoparticles synthesized therefrom 发明人:MURPHY RYAN J; DREYFUS REMI; HOUGH LAWRENCE ALAN; MALASSIS LUDIVINE; MURRAY CHRISTOPHER; DONNIO BERTRAND 权利人:RHODIA OPERATIONS; CENTRE NAT RECH SCIENT; UNIV PENNSYLVANIA 摘要:Described herein are methods of synthesizing metal nanoparticles and the metal nanoparticles synthesized therefrom. Further described in the present disclosure are methods of modifying the surfaces of metal nanoparticles and the metal nanoparticles modified thereby. Also described herein are uses of such metal nanoparticles.
专利号:US-6214875-B1 优先权日:1998-04-14 标题:Anticancer effects of specific branched-chain fatty acids and related production process 发明人:YANG ZHENHUA 摘要:A group of specific branched-chain fatty acids, with significant anticancer effects on human and animals; methods of making using either chemical synthesis or biosynthesis methods; and methods of treating cancer.
专利号:CN-106852132-A 优先权日:2014-06-20 标题:Stabilizer-free synthesis of metal nanoparticles and use of metal nanoparticles synthesized therefrom
专利号:MX-2007005591-A 优先权日:2004-11-08 标 题:SYNTHESIS OF CARDIOLIPINE ANALOGS AND USES OF THE SAME.
专利号:CN-1714095-A 优先权日:2002-10-16 标题:Cardiolipin molecules and method of synthesis
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