CAS: 14469-83-1; (5-Bromopentyl)Benzene

该化合物其结构特征为:含有一个附于五角形链的溴原子,在第五碳时进一步以一个苯组替代该物质;该化合物属于烷基卤化物类别,特别是溴甘烷,并具有此类化合物的典型特性,包括溴原子存在的中极性;该苯基组有其芳香特性,有可能影响其再活性和溶性;1-Bromo-5-苯丙烷在室内温度下可能无色无色可染,对黄黄色液体而言,其沸点相对较低,与较大,更复杂的有机分子相比,具有较复杂的有机分子.该化合物可能参与核分裂性替代反应,其中溴原子可由各种核糖类替代;此外,其结构表明在有机合成中的潜在应用,特别是在通过混合反应形成更复杂的分子方面.在处理该化合物时,应采取安全防范措施,因为它可能对卤化有机物质构成典型的健康风险.

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5-phenylpentan-1-ol Essigsaeure-(5-phenylpentyl)ester 1,5-dibromo-pentane benzonitrile acetic acid-[4-(5-phenyl-pentyloxy)-anilide] 1-(5-bromo-pentyl)-4-nitro-benzene bis-(5-phenyl-pentyl)-disulfide [5-(2,4-dinitro-phenyl)-pentyl]-(4-nitro-phenyl)-ether

合成工艺路线路线简述

    📜5-苯基戊酰氯置于lithium Aluminium Tetrahydride,硫酸,氢溴酸体系中,用 乙醚 用作溶剂,化学反应 4.0H,反应生成(5-溴正戊基)苯
    参考文献:254.一些单烷基苯的合成
    标题:254.一些单烷基苯的合成
    摘要:
    Doi:10.1039/jr9600001254

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    专利信息


    专利号:US-7781470-B2
    优先权日:1999-09-13
    标题:Aminodicarboxylic acid derivatives having pharmaceutical properties
    发明人：ALONSO-ALIJA CRISTINA; HEIL MARKUS; FLUBACHER DIETMAR; NAAB PAUL; PERNERSTORFER JOSEF; STASCH JOHANNES-PETER; WUNDER FRANK; DEMBOWSKY KLAUS; PERZBORN ELIZABETH; STAHL ELKE
    权利人:BAYER SCHERING PHARMA AG
    摘要:The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, n nwherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.

    专利号:WO-9829373-A1
    优先权日:1996-12-26
    标 题 :φ-BROMOALKYLBENZENES AND PROCESS FOR PREPARING THE SAME
    发明人：WATANABE KIYOSHI
    权利人:NIPPON ZEON CO; WATANABE KIYOSHI
    摘要:φ-Bromoalkylbenzenes reduced having a small content of positional isomer and a process for preparing the same characterized by bringing a bromoalkylbenzene mixture comprising an φ-bromoalkylbenzene and an (φ-1)-bromoalkylbenzene into contact with an acid and then separating the φ-bromoalkylbenzene therefrom. The above compounds are useful as intermediates for medicines and, for example, 4-bromobutylbenzene is an important intermediate for the synthesis of the compound represented by formula (5) and used as a remedy for asthma.

    专利号:US-2008194590-A1
    优先权日:2005-03-28
    标 题:4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors
    发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; TENBRINK RUTH ELIZABETH
    权利人:PFIZER
    摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , A 7 , A 8 , X 4 , X 6 , X 2k , R 2l , R 4 , R 5 , and R 6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

    专利号:RU-2197960-C2
    优先权日:1994-11-09
    标题:2,2-dichloroalkane carboxylic acids, method of their synthesis, medicinal agents containing thereof and their application for treatment of insulin resistance

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    合成参考文献


    摘要:Shu, X.-Z.; Pang, X., Science of Synthesis: Special Topics, (2022) 1, 404.
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