CAS: 14206-58-7; (4R,4Ar,5S,5Ar,6S,12Ar)-4-(Dimethylamino)-1,5,6,10,11,12A-Hexahydroxy-6-Methyl-3,12-Dioxo-4,4A,5,5A-Tetrahydrotetracene-2-Carboxamide

该化合物是一种复杂的有机化合物,其特征是复杂的多周期结构和多种功能组.它具有若干氢氧基化合物组的四环状框架,有助于其在极溶剂中的潜在溶解性,以及在不同化学环境中的再活性.由于存在氨基和氢氧化物组群,它可能具有基本和酸性特性,可以与其他分子如氢结合.此外,三甲基氨基团表示一种可传播化学特性的化合物结构,可以传播其特性,在生物系统中或作为功能化学领域的化学领域.

英文名称(4R,4Ar,5S,5Ar,6S,12Ar)-4-(Dimethylamino)-1,5,6,10,11,12A-Hexahydroxy-6-Methyl-3,12-Dioxo-4,4A,5,5A-Tetrahydrotetracene-2-Carboxamide
中文名称4-差向土霉素
IUPAC名称(4R,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
其它别名4-EPIOXYTETRACYCLINE, 'CAN BE USED AS SECONDARY STANDARD', 97; 4-Epioxytetracycline, 'can be used as secondary standard', ; 4-Epioxytetracycline,,'can be used as secondary standard'
CAS编号14206-58-7
MFCD编号:MFCD00021181
FDA UNII编号:73VON8SRY5
分子式:C22H24N2O9分子量:460.441
产品CID: 643098
产品分类原料药 → 抗生素类药物 → 四环素类药

相似结构搜索
InChIKey: IWVCMVBTMGNXQD-DVJPNYBFSA-N
1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31)/t12-
计算化学: 氢键受体数10.0氢键供体数7.0可旋转键数2.0

MSDS等安全信息

UN编号NONH for all modes of transport

上下游产品

Oxytetracycline

合成工艺路线路线简述

📜土霉素置于溶剂黄146体系中,化学反应生成4-差向土霉素
参考文献:Studies Of The Reversible Epimerization occurring In The Tetracycline Family. The Preparation,Properties And Proof Of Structure Of Some 4-Epi-Tetracyclines
标题:Studies Of The Reversible Epimerization occurring In The Tetracycline Family. The Preparation,Properties And Proof Of Structure Of Some 4-Epi-Tetracyclines
摘要:
Doi:10.1021/ja01568A050

海关参考信息

2901210000-乙烯
2901220000-丙烯
2902500000-苯乙烯
2902600000-乙苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-2005130919-A1
优先权日:2003-07-18
标题:Regulatable promoters for synthesis of small hairpin RNA
发明人：XU ZUOSHANG; XIA XUGANG
权利人:UNIV MASSACHUSETTS
摘要:The present invention provides compositions for RNA interference and methods of use thereof. The present invention is based on the development of promoters that can be used to regulate shRNA expression spatially (in specific cells) and temporally (at specific times) in cells or transgenic animals that express a recombinase. The compositions and methods of the present invention feature regulatable promoters that allow for inhibition of the expression of target alleles in a spatially and temporally regulatable manner. Thus, the compositions of the present invention are useful for investigating gene functions, both physiologic and pathologic, in specific cell groups and in specific ages, in normal and disease pathways. Functional and genomic and proteomic methods are featured. Therapeutic methods are also featured.

专利号:WO-2005007877-A2
优先权日:2003-07-18
标题:Regulatable promoters for synthesis of small hairpin rna

其他信息查阅

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

实用工具

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主要参考文献

1. Wu, X., Wei, Y., Zheng, J., et al. The behavior of tetracyclines and their degradation products during swine manure composting. Bioresour. Technol. 102(10), 5924-5931 (2011). 2. Çelik, A., Casey, E., and Hasar, H. Degradation of oxytetracycline under autotrophic nitrifying conditions in a membrane aerated biofilm reactor and community fingerprinting. J. Hazard. Mater. (2018).