CAS: 121-72-2; N,N,3-Trimethylaniline

相似化合物

4913-13-7 99-97-8 619-22-7

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CAS号50-00-0 甲醛 | CAS号108-44-1 3-甲基苯胺 | CAS号591-17-3 3-溴甲苯 | CAS号67530-30-7 N,N-dimethyl O-... | CAS号108-41-8 间氯甲苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号13061-96-6 甲基硼酸 | CAS号124-38-9 二氧化碳 | CAS号696-44-6 N-甲基间甲苯胺 | CAS号50638-50-1 4-溴-N,N,3-三甲基苯胺 | CAS号1343610-01-4 N-methyl-N-(m-t... | CAS号42883-79-4 N-甲基-N-苯基丁酰胺 | CAS号108-38-3 间二甲苯 | CAS号24619-07-6 4-[bis[4-(dimet... | CAS号29785-93-1 Benzenamine,N,N... | CAS号54-88-6 4-(二甲氨基)-2-甲基偶氮苯 | CAS号1193-18-6 3-甲基-2-环己烯-1-酮 | CAS号1199-59-3 4-二甲氨基邻甲苯醛 | CAS号137-17-7 2,4,5-三甲基苯胺

4-Chloro-3-Methyl-N,N-Dimethylaniline 以 异丙醇 用作溶剂,化学反应 30.0H,以89%的收率获得n,N-二甲基-间甲基苯胺
参考文献:Solarylations Via 4-Aminophenyl Cations
标题:Solarylations Via 4-Aminophenyl Cations
摘要:The Application Of The Photo-S(N)1 Reaction On Sonic 4-Chloroanilines Was Explored Under Solar Irradiation In View Of Obtaining A Convenient Metal-Free Arylation Method. Several Reactions Previously Carried Out By Uv Irradiation,As Well As Some New Ones,Where Either A New Trap (Alpha-Methylstyrene) Ora New Halide (N,N-Dimethyl-4-Fluoroaniline) Were Adopted,Were Studied Under These Conditions And Found To occur Conveniently. Furthermore,At Least In Some Cases The Halide Starting Concentration Could Be Raised Up To 0.2 M,The Excess Trapping Agent Reduced From 20:1 To 2.5:1,And The Solvent Replaced By More Environmentally Friendly (Co)Solvents Including Water. Under These Improved Conditions,The Photoarylation Was Carried Out In A Gram Scale By Merely Exposing The Solution To Solar Irradiation. This Process Has A Low Impact On The Environment And Can Be Considered A Serious Competitor Of Metal-Catalyzed Arylations.
Doi:10.1021/jo902669J

专利信息

专利号:US-6951878-B2
优先权日:1998-03-12
标 题:Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases)
发明人：MOELLER NIELS PETER HUNDAHL; ANDERSEN HENRIK SUNE; IVERSEN LARS FOGH; OLSEN OLE HVILSTED; BRANNER SVEN; HOLSWORTH DANIEL DALE; BAKIR FARID; JUDGE LUKE MILBURN; AXE FRANK URBAN; JONES TODD KEVIN; RIPKA WILLIAM CHARLES; GE YU; UYEDA ROY TERUYUKI
权利人:NOVO NORDISK AS
摘要:The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. n The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:US-8642798-B2
优先权日:2004-12-07
标 题:Silacycle compounds and methods of use thereof
发明人：LEIGHTON JAMES LINCOLN; BERGER RICHARD; SHIRAKAWA SEIJI; NOTTE GREGORY T
权利人:LEIGHTON JAMES LINCOLN; BERGER RICHARD; SHIRAKAWA SEIJI; NOTTE GREGORY T; TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
摘要:The present invention relates to a diastereomeric mixture of Silacycle Compounds and methods for using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis.

专利号:US-8106031-B2
优先权日:2006-05-02
标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-9650329-B2
优先权日:2013-06-25
标题:Transition-metal-free N-arylation of tertiary amines using arynes
发明人：BIJU AKKATTU THANKAPPAN; BHOJGUDE SACHIN SURESH; KAICHARLA TRINADH
权利人:COUNCIL SCIENT IND RES; COUNCIL SCIENT IND RES
摘要:The present invention relates to transition-metal-free process for the synthesis of tertiary arylamines comprises coupling reaction between arynes and N,N-dimethyl aniline compounds in presence of 18-crown-6, KF and THF.

专利号:US-5786448-A
优先权日:1996-11-07
标题:Combinatorial libraries of cyclic urea and cyclic thiourea derivatives and compounds therein
发明人：NEFZI ADEL; OSTRESH JOHN M; HOUGHTEN RICHARD
权利人:TREGA BIOSCIENCES INC
摘要:The invention provides a rapid approach for combinatorial synthesis and screening of libraries of cyclic urea and cyclic thiourea compounds. The present invention further provides the compounds made by the combinatorial synthesis.

专利号:US-2024100563-A1
优先权日:2020-10-14
标 题 :Enhanced copolymer synthesis methods and applications thereof
发明人：WYATT QUINTON K; YOUNG MATTHIAS J; KINLEN PATRICK J; PARANAMANA NIKHILA C
权利人:UNIV MISSOURI
摘要:Unique polymers and copolymers generated via oMLD processes are described alongside the methods for tuning such polymer and copolymer structures and redox chemistries. The polymers and copolymers described can incorporate monomeric species previously held to have too high an oxidation potential for successful use in oMLD, can exhibit unexpected redox chemistry from the adjustable incorporation of primary amine monomers and resulting azo functional groups, and show superior performance metrics when compared to polymers and copolymers synthesized by other methods. Applications for these polymers and copolymers are also described.