CAS: 117445-22-4; 3-(((Tert-Butoxycarbonyl)Amino)Methyl)Benzoic Acid

该化合物是一种化学化合物,其特点是存在一种与氨基甲基组和三丁基氧碳基(Boc)保护组的苯并二甲酸,该组通常用于有机合成,以在各种化学反应中保护氨胺,允许有选择的功能化.该组通常具有芳香和碳酸功能的特性,包括有机溶剂中的潜在溶性以及由于碳信化酸组而具有的中度酸性.氨基甲基酸组的存在表明,它可以参与进一步的化学反应,如组合反应或核聚变替代.其结构允许在浸酸合成和药用化学中应用,特别是在开发药物时,因为防雷药至关重要.

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上下游产品

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 3-aminomethylbenzoic acid 3-(aminomethyl)benzoic acid hydr°Chloride tert-butyl dicarbonatedi-tert-butyl dicarbonateB°C-Mamb-Ox 3-{[(tert-butoxycarbonyl)amino]methyl}cyclohexanecarboxylic acid cyclo(D-Ala-Arg-Gly-Asp-Mamb) cyclo(Ala-Arg-Gly-Asp-Mamb)

合成工艺路线路线简述

    📜间甲基苯甲酸置于偶氮二异丁腈 N-溴代丁二酰亚胺(Nbs),氯化亚砜,水,碳酸氢钠,一水合肼,Lithium Hydroxide体系中,用 四氢呋喃,甲醇,四氯化碳,水,乙酸乙酯,N,N-二甲基甲酰胺 用作溶剂,化学反应 25.17H,反应生成3-(N-Boc-氨甲基)苯甲酸
    参考文献:Histone Deacetylase Inhibitors
    标题:Histone Deacetylase Inhibitors
    摘要:该披露提供了i式化合物及其制备方法.这些化合物作为组蛋白去乙酰化酶的抑制剂.

    海关参考信息

    专利信息


    专利号:US-5817749-A
    优先权日:1993-03-29
    标 题:Processes and intermediate compounds for the preparation of platelet glycoprotein IIb/IIIa inhibitors
    发明人:ZHANG LIN-HUA; MA PHILIP; DEGRADO WILLIAM FRANK
    权利人:DU PONT PHARM CO
    摘要:This invention provides processes for the synthesis of platelet glycoprotein IIb/IIIa inhibitors and intermediate compounds useful in said processes. The compounds afforded by this invention have the formula: Formula (I)

    专利号:US-2023295613-A1
    优先权日:2020-02-14
    标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
    发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
    权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
    摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

    专利号:US-8450529-B2
    优先权日:2008-10-02
    标 题:Branched polyamines and formulations thereof for use in medical devices
    发明人:KAPIAMBA MBIYA
    权利人:KAPIAMBA MBIYA; COVIDIEN LP
    摘要:The present disclosure provides for the synthesis of branched polyamines. In embodiments, branched polyamines may be formed by reacting a branched polyol with a nitroaryl carboxylic acid to form a nitrobenzoyl ester which, in turn, may then be subjected to a hydrogenating step to form the branched polyamine. The resulting branched polyamine may then be reacted with another hydrogel precursor to form a hydrogel.

    专利号:NZ-263455-A
    优先权日:1993-03-29
    标题:Synthesis of platelet glycoprotein iib/iiia inhibitors

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献

    合成方法参考DOI号:10.1016/S0040-4039(00)78178-0
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