专利号:US-5817749-A 优先权日:1993-03-29 标 题:Processes and intermediate compounds for the preparation of platelet glycoprotein IIb/IIIa inhibitors 发明人:ZHANG LIN-HUA; MA PHILIP; DEGRADO WILLIAM FRANK 权利人:DU PONT PHARM CO 摘要:This invention provides processes for the synthesis of platelet glycoprotein IIb/IIIa inhibitors and intermediate compounds useful in said processes. The compounds afforded by this invention have the formula: Formula (I)
专利号:US-2023295613-A1 优先权日:2020-02-14 标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming 发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:US-8450529-B2 优先权日:2008-10-02 标 题:Branched polyamines and formulations thereof for use in medical devices 发明人:KAPIAMBA MBIYA 权利人:KAPIAMBA MBIYA; COVIDIEN LP 摘要:The present disclosure provides for the synthesis of branched polyamines. In embodiments, branched polyamines may be formed by reacting a branched polyol with a nitroaryl carboxylic acid to form a nitrobenzoyl ester which, in turn, may then be subjected to a hydrogenating step to form the branched polyamine. The resulting branched polyamine may then be reacted with another hydrogel precursor to form a hydrogel.
专利号:NZ-263455-A 优先权日:1993-03-29 标题:Synthesis of platelet glycoprotein iib/iiia inhibitors