CAS: 1122-81-2; 4-Propylpyridine

该化合物是属于类的有机化合物,是含有环内氮原子的芳香热循环化合物,这种特殊化合物具有附于环内氮原子的四碳的丙基化合物组,影响环的物理和化学特性.它一般是粉黄的无色液体,具有典型的气味. 4-popylpyridine在有机溶剂中溶解,在水中表现出中等溶解性.它的分子结构有助于其再活动,使其成为有机合成和生产各种药品和农用化学物的有用中间体.该化合物还可能显示出该环内氮原子的基本特性,使其能够参与质子反应.安全数据表明,应当谨慎处理,因为它可能会对皮肤和眼睛产生刺激.

结构式图片

相似化合物

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合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于盐酸,Palladium On Activated Charcoal体系中,化学反应生成4-正丙基吡啶
    参考文献:Suzuki,Pharmaceutical Bulletin,1956,Vol. 4,P. 211,212,214
    标题:Suzuki,Pharmaceutical Bulletin,1956,Vol. 4,P. 211,212,214

    海关参考信息

    专利信息


    专利号:WO-9955664-A1
    优先权日:1998-04-24
    标 题 :Preparation of carbocyclic compounds
    发明人:BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
    权利人:GILEAD SCIENCES INC; BECKER MARK W; CHAPMAN HARLAN H; KELLY DAPHNE E; KENT KENNETH M; LEW WILLARD; LOUIE MICHAEL S; MCGEE LAWRENCE R; PRISBE ERNEST J; POSTICH MICHAEL J; ROHLOFF JOHN C; SCHULTZE LISA M; YU RICHARD H; ZHANG LIJUN
    摘要:The present invention provides new synthetic methods and compositions. In particular, new methods of preparing intermediates useful in the synthesis of neuraminidase inhibitors and compositions useful as intermediates that are themselves useful in the synthesis of neuraminidase inhibitors are provided.

    专利号:US-9802952-B2
    优先权日:2013-07-15
    标 题:Method and apparatus for the synthesis of dihydroartemisinin and artemisinin derivatives
    发明人:KOPETZKI DANIEL; MCQUADE DAVID TYLER; SEEBERGER PETER H; GILMORE KERRY
    权利人:MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V; MAX-PLANK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS E V
    摘要:The present invention is directed to a method for continuous production of dihydroartemisinin and also artemisinin derivatives derived from dihydroartemisinin by using artemisinin or dihydroartemisinic acid (DHAA) as starting material as well as to a continuous flow reactor for producing dihydroartemisinin as well as the artemisinin derivatives. It was found that the reduction of artemisinin to dihydroartemisinin in a continuous process requires a special kind of reactor and a special combination of reagents comprising a hydride reducing agent, at least one activator such as an inorganic activator, at least one solid base, at least one aprotic solvent and at least one C 1 -C 5 alcohol.

    专利号:US-4388310-A
    优先权日:1982-03-01
    标 题:6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
    发明人:CHRISTENSEN BURTON G; DININNO FRANK P; MUTHARD DAVID A; RATCLIFFE RONALD W
    权利人:MERCK & CO INC
    摘要:Disclosed are 6-amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids (I) which are useful as antibiotics and as intermediates in the synthesis of substituted pen-2-em-3-carboxylic acids: I wherein: R1 is H or acyl; R2 is hydrogen or methoxyl; R3 is alkyl having from 1-6 carbon atoms; phenylalkyl having 7-12 carbon atoms; and cycloalkyl having 3-6 carbon atoms; and R4 is hydrogen, a removable protecting group or a pharmaceutically acceptable salt or ester moiety.

    专利号:US-3919155-A
    优先权日:1970-12-18
    标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
    发明人:SQUIRE EDWARD NOONAN
    权利人:DU PONT
    摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.

    专利号:WO-2012002913-A1
    优先权日:2010-07-02
    标 题:Process of forming a cyclic imide
    发明人:HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
    权利人:UNIV NANYANG TECH; HONG SOON HYEOK; ZHANG JIAN; MUTHAIAH SENTHILKUMAR; GHOSH SUBHASH CHANDRA
    摘要:A process is provided for the synthesis of a cyclic imide. A primary amine and a diol compound are contacted in the presence of a Ruthenium (II) complex. The Ruthenium (II) catalyst includes at least one of an alicyclic ligand, an aromatic ligand, an arylalicyclic ligand, an arylaliphatic ligand and a phosphine ligand.

    专利号:US-3591592-A
    优先权日:1968-03-29
    标 题:Synthesis of disubstituted pyridines
    发明人:ANDERSON PAUL S
    权利人:MERCK & CO INC
    摘要:BY INTRODUCING AN ALKYL OR ARYL GROUP INTO THE 2-POSITION OF A 4-ALKYL OR 4-ARYL PYRIDINE WITH AN ALKYL OR ARYL LITHIUM REAGENT 2,4-ALKYL AND ARYL PYRIDINE COMPOUNDS CAN BE CONVENIENTLY PREPARED.
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    合成参考文献


    摘要:A. Fischer, W.J. Galloway and J. Vaughan. J. Chem. Soc., B 1964, 3591.
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