CAS: 9005-27-0; Hydroxyethyl Starch

专利信息

专利号:US-2010304368-A1
优先权日:2006-09-20
标 题:Components and method for enzymatic synthesis of nucleic acids
发明人：CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
权利人:CHERKASOV DMITRY; BAEUML ENGLEBERT; BAEUML ELISABETH
摘要:Novel methods for enzymatic synthesis of nucleic acid chains and the substrates for the same are disclosed. The methods are based on a step-wise enzymatic reaction. The sequencing of nucleic acids is an example of the use of the claimed methods.

专利号:US-2023416243-A1
优先权日:2020-11-06
标 题 :Process for Preparing Heterocyclic Methanone Compounds and AZA-Bicyclo Intermediates Thereof
发明人：GRUGEL CHRISTIAN
权利人:ACTINOGEN MEDICAL LTD
摘要:The present disclosure relates to a process for synthesis of heterocyclic methanone compounds, and in particular 3′-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds, and aza-bicyclo intermediates thereof. In particular, the present disclosure also relates to a process for the synthesis of Xanamem. The present disclosure also relates to a process for the synthesis of optionally protected aza-bicyclo intermediate compounds. The present disclosure also relates to 3′-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds and aza-bicyclo intermediate compounds thereof.

专利号:US-7632654-B2
优先权日:2002-04-29
标 题:Means and methods for detecting endoglycosidase activity
发明人：AERTS JOHANNES MARIA FRANCISCU
权利人:AZ UNIV AMSTERDAM
摘要:The invention discloses a method for detecting an activity of an endoglycosidase. The method includes providing the endoglycosidase with a substrate of the endoglycosidase and detecting cleavage of the substrate. The method further includes at least partly inhibiting the transglycosidase activity of the endoglycosidase. The transglycosidase activity may be inhibited by chemically modifying the substrate such that transglycosylation of the substrate by the endoglycosidase is at least partly inhibited while the endoglycosidase is still capable of cleaving the substrate. In one embodiment, the substrate comprises an oligosaccharide chain. Compounds and kits suitable for use in a method of the invention are also disclosed. Methods involving competitive inhibitors are also disclosed as are methods for the synthesis of glycosylated substrates involving the transglycosidase activity of an endoglycosidase.

专利号:US-2017065721-A1
优先权日:2010-08-04
标题:Synthesis and use of therapeutic metal ion containing polymeric particles
发明人：PETROS ROBBY A
权利人:UNIV NORTH TEXAS
摘要:Therapeutic particles contain metal ions and are characterized by the use of unique ligand sets capable of making the metal ion complex soluble in biological media to induce selective toxicity in diseased cells. The particles may comprise a polymeric base particle, at least one pharmaceutically active metal ion, including metal ions from more than one metal element, a ligand that is covalently attached to the polymeric base particle and attached to the metal ion via a stimuli-responsive bond, and a cell targeting component. When the metal ion-containing particle enters a pre-defined environment, the ligands binding the metal to the particle are broken, triggering release of the free metal ion while the original ligands remain covalently bound to the particle.

专利号:RU-2081881-C1
优先权日:1988-01-26
标题 :Macromolecular paramagnetic compound, method of synthesis of macromolecular paramagnetic compound, diagnostic contrasting agent, method of diagnostic contrasting agent preparing

专利号:ES-2965777-T3
优先权日:2012-05-16
标 题:Enzymatic synthesis of L-nucleic acids