CAS: 729-81-7; 1,3,5-Tris(Trifluoromethyl)Benzene

上下游产品

CAS号554-95-0 均苯三甲酸 | CAS号328-70-1 1,3-双(三氟甲基)-5-溴苯 | CAS号2923-18-4 三氟乙酸钠 | CAS号455-13-0 4-碘三氟甲苯 | CAS号159566-31-1 tributyl(2,4,6-... | CAS号661-54-1 3,3,3-三氟-1-丙炔 | CAS号729-80-6 1,3,5-tris(tric... | CAS号402-31-3 间二三氟甲苯 | CAS号626-39-1 1,3,5-三溴苯 | CAS号108-67-8 均三甲苯 | CAS号108-67-8 均三甲苯 | CAS号25753-26-8 2,4,6-三(三氟甲基)苯甲酸 | CAS号725-89-3 3,5-双(三氟甲基)苯甲酸 | CAS号135130-97-1 2,4,6-三(三氟甲基)苯甲酰氯 | CAS号25753-22-4 2,4,6-三(三氟甲基)苯胺 | CAS号124927-10-2 [2,4,6-tris(tri... | CAS号114071-28-2 2,4,6-tris(trif... | CAS号650583-81-6 trichloro-[2,4,... | CAS号650583-80-5 dichloro-bis[2,... | CAS号650583-82-7 trichloro-[2,4,...

间二三氟甲苯置于copper(L) Iodide,1,3-二溴-5,5-二甲基海因,硫酸体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 30.0H,反应生成 1,3,5-三(三氟甲基)苯
参考文献:1-Bromo-3,5-双(三氟甲基)苯:一种多用途的有机金属合成原料
标题:1-Bromo-3,5-双(三氟甲基)苯:一种多用途的有机金属合成原料
摘要:可以通过在强酸性介质中用n,N'-二溴-5,5-二甲基乙内酰脲处理1,3-双(氟甲基)苯来选择性地制备1-Bromo-3,5-双(三氟甲基)苯(1).通过3,5-双(三氟甲基)苯基镁,-锂和-铜中间体完成了许多合成上有用的反应.
DOI:10.1002/cber.19961290219

专利信息

专利号:WO-2018154244-A1
优先权日:2017-02-24
标题 :Method for the synthesis of pheromones
发明人：QUEVAL PIERRE; CAIJO FRÉDÉRIC; ROUEN MATHIEU; TRIPOTEAU FABIEN
权利人:DEMETA
摘要:The invention relates to a method for the synthesis of pheromones functionalised on one of the ends thereof and comprising at least two conjugated double bonds with a majority stereochemical configuration (E, Z). The reaction is carried out in two steps, comprising: (a) a metathesis reaction between a functionalised olefin and an unsaturated aldehyde, in the presence of at least one specific catalyst selected from the ruthenium complexes comprising a 1,3-diaryl-imidazolidin-2-yl ligand and a styrenyl ether ligand, and (b) the reaction of the product obtained in this way with a triphenylalkylphosphonium salt.

专利号:WO-2018069146-A1
优先权日:2016-10-11
标题 :Method for the synthesis of pheromones
发明人：QUEVAL PIERRE; CAIJO FRÉDÉRIC; ROUEN MATHIEU; TRIPOTEAU FABIEN
权利人:DEMETA
摘要:The present invention relates to a method for synthesising pheromones and pheromone precursors, by means of the metathesis of terminal olefins including one functionalised olefin. The reaction is carried out in the presence of at least one particular catalyst, selected from among complexes of alkylidene ruthenium comprising a 1-aryl-3-cycloalkyl-imidazoline-2-ylidene ligand and mixtures thereof. The method can include an additional step of reducing the unsaturated compound formed.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:WO-9967219-A1
优先权日:1998-06-22
标 题:Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
发明人：AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
权利人:ELAN PHARM INC; LILLY CO ELI; AUDIA JAMES E; PORTER WARREN J; THOMPSON RICHARD C; WILKIE STEPHEN C; STACK DOUGLAS R; SHI QING
摘要:Compounds of formula (I), wherein W is a cyclic group of the type (2); (3); Y is represented by the formula (II); these compounds inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6774125-B2
优先权日:1998-06-22
标 题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6509331-B1
优先权日:1998-06-22
标题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.