CAS: 71-73-8; Thiopental Sodium

专利信息

专利号:WO-2004099229-A1
优先权日:2003-05-06
标题:Process for the synthesis of base addition salts of 2,3-0-isopropylidene-1-0-substituted-5,6-dideoxy-5-n- (4-(2-hydroxy-2-oxoethyl)-phenylaminocarbonyl) amino-l-gulofuranosides
发明人：KHANNA JAG MOHAN; YADAV GYAN CHAND; RAY ABHIJIT; KRISHNA NARUGANAHALLI SIDDARAN
权利人:RANBAXY LAB LTD; KHANNA JAG MOHAN; YADAV GYAN CHAND; RAY ABHIJIT; KRISHNA NARUGANAHALLI SIDDARAN
摘要:The present invention relates to processes for the synthesis of base addition salts of particular ß-L- gulofuranosides. More specifically, the invention relates to synthetic processes for making base addition salts of 2,3-O-isopropylidene-1-O-substituted-5,6-dideoxy-5-N-[4-(2-hydroxy-2-oxoethy)-phenylaminocarbony]amino-ß-L-gulofuranosides.

专利号:WO-9925385-A1
优先权日:1997-11-17
标 题:A method of increasing nucleic acid synthesis with ultrasound
发明人：UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID
权利人:IMARX PHARMACEUTICAL CORP
摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.

专利号:US-2004067197-A1
优先权日:1997-11-26
标 题:Radiolabeled DNA carrier, method of preparation and therapeutic uses thereof
发明人：LECLERC GUY; MARTEL REMI
摘要:The present invention relates to a radiolabeled DNA carrier, a method of preparation thereof and the therapeutic uses of this substance to prevent uncontrolled cellular proliferation. The invention also relates to devices incorporating the above radiolabeled DNA carrier (such as an oligonucleotide) for the therapeutic treatment of uncontrolled cellular proliferation. More specifically, the present invention is concerned with the prevention of restenosis by intravascular delivery of radiolabeled DNA carrier at a dilatation site of an artery. This invention is also directed to a method of treatment of vascular proliferative diseases and/or other proliferative disorders such as cancer and related metastasis. More particularly, the invention relates to the preparation of DNA sequences carrying one or several radioisotopes, located within the DNA sequence, and which are able to prevent cell proliferation in vitro and, pursuant to local drug delivery and/or systemic drug delivery, are able to prevent cell proliferation in vivo, more particularly restenosis and malignant tumors. In other words, the invention relates to the synthesis process, the stability data of the radiolabeled DNA carrier, the efficacy of the invention in vitro, in cell culture, and the in vivo delivery of the molecule.

专利号:US-7781470-B2
优先权日:1999-09-13
标题:Aminodicarboxylic acid derivatives having pharmaceutical properties
发明人：ALONSO-ALIJA CRISTINA; HEIL MARKUS; FLUBACHER DIETMAR; NAAB PAUL; PERNERSTORFER JOSEF; STASCH JOHANNES-PETER; WUNDER FRANK; DEMBOWSKY KLAUS; PERZBORN ELIZABETH; STAHL ELKE
权利人:BAYER SCHERING PHARMA AG
摘要:The invention relates to compounds of formulae (II), (IV), and (VI) as shown below, n nwherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.

专利号:WO-2007080560-A2
优先权日:2006-01-16
标 题:The use of the process of induction of de novo synthesis of p-glycoprotein (p-gp) in the treatment of xenobiotic-induced intoxications in mammals

专利号:PT-103420-B
优先权日:2006-01-16
标 题 :USE OF THE INDUCTION PROCESS OF THE NEW SYNTHESIS OF GLYCOPROTEIN P (GP - P) IN THE TREATMENT OF XENOBIOTIC MAMMALS INTOXICATIONS