CAS: 63-98-9; N-Carbamoyl-2-Phenylacetamide

该化合物是抗凝固剂和止痛剂而闻名.苯丙胺的分子结构具有附属于碳基组(C=O)的联苯组和一个有助于其生物活动的安咪(NH)组,它溶于有机溶剂,但水溶性有限.Phecemide的动作机制包括调控...

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ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

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CAS号102618-95-1 6-Benzyl-2H-1,3... | CAS号111155-59-0 phenylacetylcar... | CAS号57-13-6 尿素 | CAS号103-80-0 苯乙酰氯 | CAS号103-82-2 苯乙酸

合成工艺路线路线简述

    📜Phenylacetyl-Carbamoyl Chloride置于氨体系中,用 乙醚 作为反应溶剂,化学反应 0.5H,反应生成 苯乙酰脲
    参考文献:Sidky,M. M.; El-Kateb,A. A.; Mahran,M. R.,Phosphorus And Sulfur And The Related Elements,1987,Vol. 29,P. 11-16
    标题:Sidky,M. M.; El-Kateb,A. A.; Mahran,M. R.,Phosphorus And Sulfur And The Related Elements,1987,Vol. 29,P. 11-16

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    专利信息


    专利号:WO-2011103648-A1
    优先权日:2010-02-23
    标 题:Method for preparing ointments containing antioxidants from polyphenol-rich plants for use in the treatment of wounds of various origins which involve an increase in oxidation-promoting agents and/or increased formation of oxygen-derived reactive species and/or reduced formation of nitric oxide
    发明人:SOARES DE MOURA ROBERTO
    权利人:UNIV DO ESTADO DO RIO DE JANEIRO UERJ; SOARES DE MOURA ROBERTO
    摘要:This invention relates to a method for producing oitnments and/or creams that contain antioxidants from polyphenol-rich plants such as Euterpe oleracea (assai palm), for use in the treatment of wounds, in order to accelerate the cicatrisation process, whenever there is an increase in the formation of oxidation-promoting compounds and a reduced synthesis of nitric oxide.

    专利号:US-2008214827-A1
    优先权日:2004-02-03
    标 题:Synthesis of Cyanoimino-Benzoimidazoles
    发明人:GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
    权利人:EURO CELTIQUE SA
    摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

    专利号:US-2020352889-A1
    优先权日:2011-06-03
    标题 :Cystathionine compositions and methods of treatment for health conditions
    发明人:MACLEAN KENNETH; AUSTIN RICHARD
    权利人:UNIV COLORADO REGENTS; UNIV MCMASTER
    摘要:The present invention relates to uses of and methods of treatment with cystathionine. In one embodiment, cystathionine reduces the development of toxin-induced liver and/or kidney disease induced by homocystinuria and/or acute nephropathy. In one embodiment, a cystathionine synthesis inhibitor is administered to increase tumor cell apoptosis and/or increase the efficacy of chemotherapeutic treatment. More particularly, cystathionine can protect cells against toxin-induced cellular apoptosis and/or cystathionine synthesis inhibitors can increase neuroblastoma cell kill rates during chemotherapy.

    专利号:BR-102013018473-B1
    优先权日:2012-07-24
    标题 :HERBICIDAL COMPOSITIONS COMPENDIENT 4-AMINO-3-CHLORO-5-FLUORO-6- (4-CHLORO-2-FLUORO-3-ETOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE OF THE SAME AND HERBICIDES INHIBITING THE SYNTHESIS OF VLCFA AND SYNTHESIS OF GRAIN ACID / LIPID, AND METHOD FOR UNDESIRABLE VEGETATION CONTROL

    专利号:CA-2555219-A1
    优先权日:2004-02-03
    标 题 :Synthesis of cyanoimino-benzoimidazoles

    专利号:US-8945508-B2
    优先权日:2009-10-13
    标 题 :Dendrimer compositions and methods of synthesis
    发明人:BAKER JR JAMES R; HUANG BAOHUA
    权利人:BAKER JR JAMES R; HUANG BAOHUA; UNIV MICHIGAN
    摘要:The present invention relates to novel dendrimer compounds and methods of synthesizing the same. In particular, the present invention is directed to novel polyamidoamine (PAMAM) dendrimers, novel dendrimer branching units, methods for synthesizing such novel PAMAM dendrimers and functionalized dendrimers, as well as systems and methods utilizing the dendrimers (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease diagnosis and/or therapy, etc.))).

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    主要参考文献


    1: Cahen R, Martin A, Francois B, Baltassat P, Louisot P. Creatinine metabolism impairment by an anticonvulsant drug, phenacemide. Ann Pharmacother. 1994 Jan;28(1):49-51. doi: 10.1177/106002809402800110. a preliminary report. AMA Arch Neurol Psychiatry. 1953 Oct;70(4):510-5. doi: 10.1001/archneurpsyc.1953.02320340100010. 37(12):1861-6. doi: 10.1212/wnl.37.12.1861. 147(1):17-21. doi: 10.1001/jama.1951.03670180023004. 23(4):430-7. doi: 10.1002/cpt1978234430. 72(3):297-312. Japanese. doi: 10.1254/fpj.72.297. 74(3):1264-6. doi: 10.1073/pnas.74.3.1264.
    8: Andreev E, Koopman M, Arisz L. A rise in plasma creatinine that is not a sign of renal failure: which drugs can be responsible? J Intern Med. 1999 Sep;246(3):247-52. doi: 10.1046/j.1365-2796.1999.00515.x. 71(11):1287-8. doi: 10.1002/jps.2600711126. 244(1):107-12.

    合成参考文献


    摘要:Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, -(366), 1972
    摘要:Arzneimittel-Forschung. Drug Research., 18(524), 1968 []
    摘要:USP Convention. USPDI - Drug Information for the Health Care Professional. 17th ed. Volume I. Rockville, MD: Convention, Inc., 1997. (Plus Updates)., p. 2317
    摘要:
    摘要:Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 218
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