CAS: 616-39-7; N,N-Diethylmethylamine

该化合物是一种有机化合物,被归类为第三级矿物质,其分子结构包括两个乙基组和一个附于氮原子的甲基组,该化合物一般是一种无色液体,具有典型的矿味.二乙基甲基胺在水中具有中等溶解性,在有机溶剂中具有高溶性,因而在各种化学应用中具有实用性.它主要用作有机合成的建筑块,特别是在生产药品和农用化学品方面.由于氮原子的存在,化合物具有基本特性,使得氮原子在化学反应中能够作为核分裂物.此外,二乙基甲基胺可以参与氢结合,影响其再活性和与其他物质的互动.在处理该化合物时,必须谨慎小心谨慎,因为它可能会刺激皮肤,眼睛和呼吸系统.应当遵循适当的储存和处理程序,以减少与使用该化合物有关的潜在危害.

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CAS号50-00-0 甲醛 | CAS号109-89-7 二乙胺 | CAS号127-19-5 N,N-二甲基乙酰胺(DMAC) | CAS号75-07-0 乙醛 | CAS号74-89-5 氨基甲烷 | CAS号617-84-5 N,N-二乙基甲酰胺 | CAS号617-86-7 三乙基硅烷 | CAS号102-53-4 N,N,N',N'-四乙基甲二胺 | CAS号75-52-5 硝基甲烷 | CAS号74-88-4 碘甲烷 | CAS号3166-62-9 溴甲贝那替秦 | CAS号50-00-0 甲醛 | CAS号624-78-2 N-甲基乙胺 | CAS号75-07-0 乙醛 | CAS号109-89-7 二乙胺 | CAS号3010-02-4 二乙氨基乙腈 | CAS号307-22-2 1-CHLORO-6H-DOD... | CAS号1210-12-4 9-氰基蒽 | CAS号1467-01-2 10-methylanthra...

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于水体系中,化学反应生成 N,N-二乙基甲胺
    参考文献:Stewart; Aston,Journal Of The American Chemical Society,1926,Vol. 48,P. 1650
    标题:Stewart; Aston,Journal Of The American Chemical Society,1926,Vol. 48,P. 1650

    海关参考信息

    专利信息


    专利号:US-5145957-A
    优先权日:1988-03-18
    标 题:Stereoselective synthesis of a chiral cis 3-beta hydrogen (3R) 4-aroyloxy azetidinone
    发明人:TSCHAEN DAVID M; LYNCH JOSEPH E; LASWELL WILLIAM L; VOLANTE RALPH P; SHINKAI ICHIRO
    权利人:MERCK & CO INC
    摘要:A process is described for the stereocontrolled synthesis of (3R,4R)-3-[(1R)-1-hydroxyethyl]-4-benzoyloxyazetidin-2-ones and their derivatives by cycloaddition involving an imine and a ketone, generated from 3(S)-hydroxybutyrate which are useful intermediates in the synthesis of carbapenem antibiotics.

    专利号:US-8975358-B2
    优先权日:2010-07-23
    标题 :Compositions and methods for synthesis of organic-silica hybrid materials
    发明人:SHEA KENNETH J; HU LI-CHIH
    权利人:SHEA KENNETH J; HU LI-CHIH; UNIV CALIFORNIA
    摘要:The present invention relates to compositions and methods for synthesis of organic-silica hybrid microparticles and nanoparticles. In particular, the present invention provides compositions and methods for particle size control during synthesis of organic-silica hybrid microparticles and nanoparticles.

    专利号:US-9688644-B2
    优先权日:2009-04-30
    标 题 :Synthesis of Tetracyclines and intermediates thereto
    发明人:MYERS ANDREW G; KUMMER DAVID A; LI DERUN; HECKER EVAN; DION AMELIE; WRIGHT PETER M
    权利人:HARVARD COLLEGE
    摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for substituents at positions 4a, 5, 5a, and 12a of the tetracycline ring system.

    专利号:EP-0269236-B1
    优先权日:1986-10-24
    标题:Process for synthesis of a chiral azetidinone
    摘要:A process is described for the stereo-controlled synthesis of 3-(R)-3-[1'-(R)-hydroxyethyl]-4-(R)-benzoyl-2-oxo-1-aze tidines and their derivatives which are useful intermediates in the synthesis of carbapenem antibiotics.

    专利号:EP-0333268-A1
    优先权日:1988-03-18
    标题:Process for synthesis of a chiral 3-beta hydrogen (3R) 4-aroyloxy azetidinone
    发明人:TSCHAEN DAVID M; LYNCH JOSEPH E; LASWELL WILLIAM L; VOLANTE RALPH P; SHINKAI ICHIRO
    权利人:MERCK & CO INC
    摘要:A process is described for the stereo-­controlled synthesis of (3R,4R)-3-[(1R)-1-hydroxy­ethyl]-4-benzoyloxyazetidin-2-ones and their derivatives which are useful intermediates in the synthesis of carbapenem antibiotics.

    专利号:US-6951932-B2
    优先权日:2001-10-25
    标 题:Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
    发明人:MOORMAN ALLAN R
    权利人:KING PHARMACEUTICALS RES & DEV
    摘要:The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine. Preferred methods of the invention include activating a guanosine compound followed by hydrolysis; alkylating the hydrolyzed compound with subsequent animation to provide a 2-aralkyloxyadenosine or a 2-alkoxyadenosine compound.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Catalytic Hydrogenation Of Amides To Amines Under Mild Conditions
    作者:Mario Stein,Bernhard Breit |发布日期:2013.2.18
    摘要:Under (Not So Much) Pressure: A General Method For The Hydrogenation Of Tertiary And Secondary Amides To Amines With Excellent Selectivity Using A Bimetallic Pd-Re Catalyst Has Been Developed. The Reaction Proceeds Under Low Pressure And Comparatively Low Temperature. This Method Provides Organic Chemists With A Simple And Reliable Tool For The Synthesis Of Amines.

    合成参考文献


    摘要:André-Joyaux, E.; Gnägi, L.; Meléndez, C.; Soulard, V.; Renaud, P., Science of Synthesis, (2021) , 459.
    参考文献:10.1007/s11030-005-9009-x
    摘要:Roy DR, Sarkar U, Chattaraj PK, Mitra A, Padmanabhan J, Parthasarathi R, Subramanian V, Van Damme S, Bultinck P. Analyzing toxicity through electrophilicity. Mol Divers. 2006 May;10(2):119–31. doi: 10.1007/s11030-005-9009-x.
    参考文献:10.1385/abab:79:1-3:609
    摘要:Holtzapple MT, Davison RR, Ross MK, Aldrett-Lee S, Nagwani M, Lee C, Lee C, Adelson S, Kaar W, Gaskin D, Shirage H, Chang N, Chang VS, Loescher ME. Biomass conversion to mixed alcohol fuels using the MixAlco process. Applied Biochemistry and Biotechnology. 1999 Mar;79(1-3):609–31. doi: 10.1385/abab:79:1-3:609.
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