CAS: 615-54-3; 1,2,4-Tribromobenzene

该化合物是一种溴化芳烃化合物,其特点是高热稳定性和化学抗药性;它是有机合成,特别是阻燃剂,药品和农用化学品生产的多用途中间体;该化合物的三种溴替代成分增强了其在电益替代和混合反应中的回弹性,使其对选择性功能化很有价值;其晶状固体形式确保了在标准条件下的处理和储存的方便性;由于其明确的结构和可预测的再活动,1,2,4-三溴苯被广泛用于需要精确溴化模式的研究和工业应用中;由于其潜在的毒性和环境持久性,应当遵守适当的安全措施.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

ethanol 2,5-dibromoaniline 2,4-dibromophenol 1.4-dibromobenzene 2,4,5-tribromo-benzenesulfonic acid 1,2,4-tribromo-3,5-dinitro-benzene 3,4-Dibrom-4'-trifluormethylbenzophenon 2,4,5-tribromo-benzenesulfonyl chloride

合成工艺路线路线简述

    苯胺置于亚硝酸特丁酯,Copper(Ll) Bromide体系中,用 乙腈 作为反应溶剂,化学反应生成 1,2,4-三溴苯
    参考文献:Alkyl Nitrite-Metal Halide Deamination Reactions. 2. Substitutive Deamination Of Arylamines By Alkyl Nitrites And Copper(II) Halides. A Direct And Remarkably Efficient Conversion Of Arylamines To Aryl Halides
    标题:Alkyl Nitrite-Metal Halide Deamination Reactions. 2. Substitutive Deamination Of Arylamines By Alkyl Nitrites And Copper(II) Halides. A Direct And Remarkably Efficient Conversion Of Arylamines To Aryl Halides
    摘要:
    DOI:10.1021/jo00434A017

    专利信息


    专利号:US-2006229475-A1
    优先权日:2005-04-11
    标题:Synthesis of hydroxylated hydrocarbons
    发明人:WEISS MICHAEL J; SUN SHOULI
    权利人:WEISS MICHAEL J; SUN SHOULI
    摘要:Ethylene glycol, other diols, triols, and polyols are made in an efficient manner by reacting dibromides with water in the presence of a metal oxide. An integrated process of dibromide formation, alcohol synthesis, metal oxide regeneration, and bromine recycling is also provided.

    专利号:US-6407299-B1
    优先权日:1999-06-02
    标 题:Alkyl magnesium catalyzed synthesis of ethylene and α-olefin polymers
    发明人:SEN AYUSMAN; KIM JANG SUB
    权利人:EXXONMOBIL RES & ENG CO; PENNSYLVANIA STATE RES FOUNDAT
    摘要:The present invention is a two-component catalyst system comprising (a) an alkyl magnesium (MgR 2 ) component and (b) a Lewis acid component. The catalyst system is used for catalyzing the oligomerization and polymerization of ethylene and/or α-olefins to form homopolymers and copolymers. The products range from highly linear, high molecular weight, solid polymers to highly branched, lower molecular weight oils.

    专利号:WO-2012175725-A1
    优先权日:2011-06-24
    标 题 :Solution polymerization/co-polymerization of dienes, hydrogenation of dienerubbers and hydrogenated dienerubbers
    发明人:SODDEMANN MATTHIAS; GUO SHARON; WEI ZEHNLI; LIU QINGCHUN
    权利人:LANXESS DEUTSCHLAND GMBH; SODDEMANN MATTHIAS; GUO SHARON; WEI ZEHNLI; LIU QINGCHUN
    摘要:The present invention relates to butadiene rubber polymers having low molecular weights and narrower molecular weight distributions than those known in the art. The present invention also relates to a metal-containing catalyst system, a solution polymerization process for the manufacture of said butadiene rubber, a one-pot process for the synthesis of the hydrogenated diene polymers, and a process for the hydrogenation of diene polymers.

    专利号:WO-0073359-A1
    优先权日:1999-06-02
    标题 :Alkyl magnesium catalyzed synthesis of ethylene and alpha-olefin polymers
    发明人:SEN AYUSMAN; KIM JANG SUB
    权利人:EXXONMOBIL RES & ENG CO
    摘要:The present invention is a two-component catalyst system comprising (a) an alkyl magnesium (MgR2) component and (b) a Lewis acid component. The catalyst system is used for catalyzing the oligomerization and polymerization of ethylene and/or α-olefins to form homopolymers and copolymers. The products range from highly linear, high molecular weight, solid polymers to highly branched, lower molecular weight oils.

    专利号:US-2009069606-A1
    优先权日:2005-04-11
    标题:Method of making alkoxylates
    发明人:KOMON ZACHARY JOHN ANTHONY; WEISS MICHAEL J
    权利人:GRT INC
    摘要:Ethoxylates and other alkoxylates are made in an efficient manner by reacting an organic bromide with a diol in the presence of a metal oxide. An integrated process of bromide formation, alkoxylate synthesis, metal oxide regeneration, and bromine recycling is also provided.

    专利号:US-2009227697-A1
    优先权日:2006-02-24
    标题 :Synthesis of a highly crystalline, covalently linked porous network
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    主要参考文献

    [参考文献]: E N Smith, Et Al. Various Pharmacokinetic Parameters In Relation To Enzyme-Inducing Abilities Of 1,2,4-Trichlorobenzene And 1,2,4-Tribromobenzene. J Toxicol Environ Health. 1980 Jul;6(4):737-49.
    [参考文献]: Eric Hittinger, Et Al. Synthesis And Characterization Of Cross-Linked Conjugated Polymer Milli-, Micro-, And Nanoparticles. Angew Chem Int Ed Engl. 2004 Mar 26;43(14):1808-11.
    [参考文献]: J A Szymańska, Et Al. Hepatotoxicity Of Brominated Benzenes: Relationship Between Chemical Structure And Hepatotoxic Effects In Acute Intoxication Of Mice. Arch Toxicol. 1998;72(2):97-103.
    [参考文献]: P K Freeman, Et Al. Differential Photohydrodehalogenation Reactivity Of Bromobenzenes (1,2,4-Tribromobenzene, 1,2,3,5-Tetrabromobenzene) And Pentachlorobenzene: Sunlight-Based Remediation. J Chem Technol Biotechnol. 1998 May;72(1):45-9.
    [参考文献]: Y Chaisuksant, Et Al. Effects Of Halobenzenes On Growth Rate Of Fish (Gambusia Affinis). Ecotoxicol Environ Saf. 1998 Feb;39(2):120-30.
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