CAS: 6055-52-3; Hexane-1,6-Diamine Dihydrochloride

该化合物是1,6-甲基乙胺和盐酸反应产生的盐,具有血红色特性,可以吸收环境湿度,典型地看起来像是白色晶状固体,在水中可溶解,可提高其在各种应用中的效用.1,6-丙胺本身是一种直链脂二胺,有助于其再活动,特别是形成聚酰胺和其他聚合物.盐酸形式通常用于稳定矿物质并改善其处理特性,用于生产粘合剂,涂层和作为环氧树脂的固化剂.此外,该化合物还可用于合成药物和农用化学物.在处理该物质时,必须采取安全防范措施,因为它可能刺激皮肤,眼睛和呼吸系统.

结构式图片

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51857-17-1 65915-94-8 945923-91-1

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ECHA物质C&L通报REACH预注册

上下游产品

N,N,N',N'-Tetrakis(trimethylsilyl)-1,6-hexandiamin methanol hexamethylenediammonium galactarate 1,6-Hexanediamine N,N-dimethyl-1,6-hexanediamine chlorhexidine 3-cyano-N1-guanidino)hexane1,6-di-(N3-cyano-N1-guanidino)hexane 2-ethyl-pyrrolidine

合成工艺路线路线简述

    专利信息


    专利号:US-5783685-A
    优先权日:1988-12-16
    标题 :Chemical preparation of high specific activity nucleotide probes
    发明人:BAHL CHANDER; MENDOZA LEOPOLDO
    权利人:ORTHO DIAGNOSTIC SYSTEMS INC
    摘要:Methods of chemical synthesis of labeled nucleotide probes are described. The methods comprise providing a first target recognition moiety comprising a nucleotide sequence of at least about 15 nucleotide bases including at least one 5' end and 3' end. The first target recognition moiety is chemically altered to contain a carboxyl group. A second signal generating moiety comprising a hydroxyl group is provided. The carboxyl group of the first target recognition moiety is chemically reacted with hydroxyl group of the second signal generating moiety to chemically join the two moieties and produce said labeled nucleotide probe.

    专利号:US-5538872-A
    优先权日:1988-12-21
    标题 :Method of preparing nucleotide probes using a bridging complement
    发明人:BAHL CHANDER; MENDOZA LEOPOLDO; MCMAHON FRANK J
    权利人:ORTHO DIAGNOSTIC SYSTEMS INC
    摘要:The present invention provides labeled nucleotide probes and a procedure for synthesis of the labeled nucleotide probe by a coupling or joinder of two components of the probe, namely a target recognition sequence moiety and a signal generating moiety, through the use of a bridging complement that holds the two moieties in such a position as to allow formation of a sugar-phosphate chemical linkage between the 3' end of one moiety and the 5' end of the other moiety.

    专利号:US-7851658-B2
    优先权日:2004-08-17
    标 题:Palladium-catalyzed carbon-carbon bond forming reactions
    发明人:LIU DAVID R; KANAN MATTHEW W; ROZENMAN MARY M
    权利人:HARVARD COLLEGE
    摘要:A novel palladium-mediated carbon-carbon bond forming reaction has been discovered using DNA-templated chemistry. The inventive reaction involves the palladium-mediated coupling of a terminal alkyne with an alkene to form an enone. A catalytic amount of palladium may be used in the reaction if an oxidant is present. The reactions is also compatible with a variety of organic solvent as well as aqueous solution. Both intermolecular and intramolecular reactions have been demonstrated. This novel carbon-carbon bond forming reaction is particularly useful in the synthesis of macrocycles. Kits, reagents, catalysts, solvents, oxidants, salts, acids, instructions, and other materials useful in the practice of the inventive reaction are also provided.

    专利号:US-6316669-B1
    优先权日:1998-12-18
    标 题:Bis-amido polybiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions
    发明人:PARK JOONSUP; MCQUEEN NATHANIEL D
    权利人:ALCON MFG LTD
    摘要:Bis-amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of bis-amido polybiguanides is also disclosed. The bis-amido polybiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic and otic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting/cleaning contact lenses.
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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Ahmed Besheer, Et Al. Enzymatically Catalyzed Conjugation Of A Biodegradable Polymer To Proteins And Small Molecules Using Microbial Transglutaminase. Methods Mol Biol. 2011:751:17-27.
    [参考文献]: Jeong Ah Byun, Et Al. Analysis Of Polyamines As Carbamoyl Derivatives In Urine And Serum By Liquid Chromatography-Tandem Mass Spectrometry. Biomed Chromatogr. 2008 Jan;22(1):73-80.
    [参考文献]: Jie Meng, Et Al. Effects Of Long And Short Carboxylated Or Aminated Multiwalled Carbon Nanotubes On Blood Coagulation. Plos One. 2012;7(7):E38995.
    [参考文献]: Leman Tarhan, Et Al. Immobilization Of Phenylalanine Dehydrogenase And Its Application In Flow-Injection Analysis System For Determination Of Plasma Phenylalanine. Appl Biochem Biotechnol. 2011 Jan;163(2):258-67.
    [参考文献]: Linda G T Gaines, Et Al. Effect Of Creatinine And Specific Gravity Normalization On Urinary Biomarker 1,6-Hexamethylene Diamine. J Environ Monit. 2010 Mar;12(3):591-9.

    合成参考文献


    摘要:Li, H.; Wang, Y.; Liu, Q., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 591.
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