CAS: 372-39-4; 3,5-Difluoroaniline

上下游产品

CAS号109-86-4 乙二醇甲醚 | CAS号7803-57-8 水合肼 | CAS号1634-04-4 甲基叔丁基醚 | CAS号372-38-3 1,3,5-三氟苯 | CAS号2265-94-3 3,5-二氟硝基苯 | CAS号364-30-7 2,4-二氟-6-硝基苯胺 | CAS号399-36-0 2',4'-二氟乙酰苯胺 | CAS号7664-93-9 硫酸 | CAS号319-88-0 1,3,5-三氯-2,4,6-三氟苯 | CAS号315-14-0 2,4,6-三氟硝基苯 | CAS号455-40-3 3,5-二氟苯甲酸 | CAS号5509-65-9 2,6-二氟苯胺 | CAS号311346-69-7 4-氯-5,7-二氟喹啉-3-甲酸乙酯 | CAS号372-38-3 1,3,5-三氟苯 | CAS号1435-43-4 1-氯-3,5-二氟苯 | CAS号461-96-1 1-溴-3,5-二氟苯 | CAS号198077-69-9 N-(3,5-二氟-苯基)-甲酰胺 | CAS号1111790-44-3 N-(3,5-difluoro...

1-溴-3,5-二氟苯置于copper(I) Oxide,1-D-O-Methyl-Chiro-Inositol,氨,Sodium Hydroxide体系中,用 水 用作溶剂,化学反应 12.0H,以94%的收率获得3,5-二氟苯胺
参考文献:铜和1-(-)-邻苯二酚在空气中催化芳基卤化物的羟基化和胺化
标题:铜和1-(-)-邻苯二酚在空气中催化芳基卤化物的羟基化和胺化
摘要:1-(-)-木瓜醇,一种从橡胶工业废水中获得的天然产物,被用作铜催化的羟基卤化和芳基卤化物胺化的有效配体,以选择性地在水中或95%的乙醇中生成酚和芳基胺.另外,在空气中以100G的规模验证了2-氯-4-羟基苯甲酸的羟基化.
Doi:10.1016/j.Tetlet.2020.152222

专利信息

专利号:US-11976021-B2
优先权日:2022-06-27
标 题:Synthesis of tetrahydronaphthalenols and uses thereof
发明人：VULIGONDA VIDYASAGAR
权利人:IO THERAPEUTICS INC
摘要:Provided herein are compounds and synthetic methods useful for preparing tetrahydronaphthalenol derivatives, and uses of the compounds prepared.

专利号:WO-2024028893-A1
优先权日:2022-08-01
标 题:Substituted benzimidazoles for treating viral diseases
发明人：CHAUDHARI VINOD DINKAR; THAKUR KRISHAN GOPAL; RINGE RAJESH PRAKASH; SINGH DESHKANWAR; KAUR SIMRAN; CHAWLA RAVNEET SINGH; JOSHI AKSHAY
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
摘要:The invention relates to benzimidazole compounds, pharmaceutically acceptable salts thereof and its pharmaceutical compositions for reducing/treating viral infections. The present invention also relates to synthesis of such benzimidazole compounds. The present invention further relates to compositions which comprise such benzimidazole compounds or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination. The compounds of the invention are useful in reducing/treating viral infections particularly coronavirus infections caused by SARS-CoV, MERS-CoV and SARS-CoV-2.

专利号:US-9376400-B2
优先权日:2005-06-08
标 题:Process for the synthesis of triazoles
发明人：CHEN SHILI; LOU RONGLIANG; WU YUSHENG; ZHOU JIACHENG; HANSELMANN ROGER
权利人:MELINTA THERAPEUTICS INC
摘要:The present invention relates to processes for the preparation of triazoles. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

专利号:US-6642390-B2
优先权日:2001-07-11
标 题:One step synthesis of 1,2,3-triazole carboxylic acids
发明人：KOLB HARTMUTH C; CAVALLARO CULLEN; SHI ZHI-CAI; GONTCHAROV ALEXANDER; WANG ZHI-MIN; RICHARDSON PAUL F; KANAMARLAPUDI RAMANAIAH C
权利人:LEXICON PHARMACEUTICALS INC
摘要:Disclosed is a one step method for preparing a 1,2,3-triazole carboxylic acid by treating an azide with a beta-ketoester in the presence of a base.

专利号:WO-9925385-A1
优先权日:1997-11-17
标 题:A method of increasing nucleic acid synthesis with ultrasound
发明人：UNGER EVAN C; MCCREERY THOMAS; SADEWASSER DAVID
权利人:IMARX PHARMACEUTICAL CORP
摘要:The present invention is directed to a method of increasing nucleic acid synthesis in a cell comprising administering to the cell a therapeutically effective amount of ultrasound for a therapeutically effective time such that said administration of said ultrasound results in said increased nucleic acid synthesis. The nucleic acid sequence may comprise an endogenous sequence or an exogenous sequence.

专利号:US-6774125-B2
优先权日:1998-06-22
标 题:Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：AUDIA JAMES E; THOMPSON RICHARD C; WILKIE STEPHEN C; BRITTON THOMAS C; PORTER WARREN J; HUFFMAN GEORGE W; LATIMER LEE H
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.