CAS: 2122-63-6; 4-Amino-3-Iodobenzoic Acid

上下游产品

CAS号19718-49-1 4-氨基-3-碘苯甲酸甲酯 | CAS号62875-84-7 4-氨基-3-碘苯甲酸乙酯 | CAS号150-13-0 对氨基苯甲酸 | CAS号94-09-7 对氨基苯甲酸乙酯 | CAS号619-45-4 4-氨基苯甲酸甲酯 | CAS号29289-13-2 2-碘-4-甲基苯胺 | CAS号29289-16-5 N-(2-iodo-4-met... | CAS号190071-24-0 4-乙酰氨基-3-碘苯甲酸 | CAS号7647-01-0 盐酸 | CAS号7790-99-0 一氯化碘 | CAS号110073-82-0 2-苯基-5-吲哚羧酸 | CAS号190071-23-9 4-乙酰氨基-3-碘苯甲酸甲酯 | CAS号190071-24-0 4-乙酰氨基-3-碘苯甲酸 | CAS号35674-20-5 3,4-二碘苯甲酸 | CAS号126632-02-8 iodoazidopotentidine | CAS号126632-01-7 iodoaminopotentidine | CAS号19718-49-1 4-氨基-3-碘苯甲酸甲酯 | CAS号190071-25-1 2-苯基-1H-吲哚-5-羧酸甲酯 | CAS号62875-84-7 4-氨基-3-碘苯甲酸乙酯

对氨基苯甲酸置于碘体系中,用 水 用作溶剂,以88 %的收率获得4-氨基-3-碘苯甲酸
参考文献:使用新型路易斯碱加合物 (Lba) [dbbur]+br− 和 [dbui]+i− 作为绿色试剂,在水中对苯酚和苯胺进行温度调节的高度区域选择性单卤化和二卤化:一种简单的方法
标题:使用新型路易斯碱加合物 (Lba) [dbbur]+br− 和 [dbui]+i− 作为绿色试剂,在水中对苯酚和苯胺进行温度调节的高度区域选择性单卤化和二卤化:一种简单的方法
摘要:在此,报道了使用易于获得且高度稳定的路易斯碱加合物(lba)对水中苯酚和苯胺进行操作简单的温度依赖性区域选择性卤化.这些新发现的lba [dbubr] + Br-和[dbui] + I-与多种底物相容,可进行区域选择性溴化和碘化,具有优异的收率(高达95%),并且只需通过过滤和分离即可直接分离产物.无需柱色谱纯化即可表征.有机碱 Dbu 被回收并重新用于制备相应的 Lba,而活性没有显着损失.进一步的卤化是化学选择性和核选择性的,并且以非常好的e因子进行.苯胺和苯酚对于单卤化的互补区域选择性(邻位优于对位)是该方法的独特特征.
Doi:10.1039/d3Nj03370H

专利信息

专利号:US-5856496-A
优先权日:1996-05-23
标题 :Combinatorial solid phase synthesis of a library of indole derivatives
发明人：FAGNOLA MARIA CHIARA; BEDESCHI ANGELO; CANDIANI ILARIA; VISENTIN GIUSEPPINA; MONGELLI NICOLA
权利人:PHARMACIA & UPJOHN SPA
摘要:PCT No. PCT/EP97/02600 Sec. 371 Date Jan. 12, 1998 Sec. 102(e) Date Jan. 12, 1998 PCT Filed May 13, 1997 PCT Pub. No. WO97/44319 PCT Pub. Date Nov. 27, 1997A process for preparing libraries of indole compounds by solid phase synthesis in the presence of organometallic catalysts. The resulting compounds have a very high purity degree, which allows biological testing on the crude products with a high confidence degree, without any cross contaminations.

专利号:US-7427260-B2
优先权日:2001-03-30
标 题:Efficient methods for solid phase synthesis using trityl chloride resins
发明人：PANG YUAN-PING; PARK JEWN GIEW
权利人:MAYO FOUNDATION
摘要:Disclosed are efficient methods for loading amino derivatives onto trityl chloride resins and for cleaving chemically modified amino derivatives from trityl chloride resins. Methods for making a library of discrete chemically modified amino derivatives also disclosed.

专利号:WO-9744319-A1
优先权日:1996-05-23
标 题:Combinatorial solid phase synthesis of a library of indole derivatives

专利号:DE-69718761-T2
优先权日:1996-05-23
标 题 :COMBINATIVE SOLID-PHASE SYNTHESIS OF A LIBRARY OF INDOLDER DERIVATIVES

专利号:EP-0854865-B1
优先权日:1996-05-23
标题:Combinatorial solid phase synthesis of a library of indole derivatives

专利号:EP-0854865-A1
优先权日:1996-05-23
标 题:Combinatorial solid phase synthesis of a library of indole derivatives