CAS: 1904-58-1; 2-Aminobenzhydrazide

该化合物是有机化合物,其特点是存在一个氨基氨基化合物和一个附属于苯环的氢氮功能组,通常看起来像白色的离白晶状固体,在水和各种有机溶剂中可溶解,该化合物以其反应性而著称,特别是形成氢氮和其他衍生物,使其在各种化学合成物中有用,该化合物在制药,农用化学品和作为分析化学的试剂中都有应用,氨基化合物有助于其基本性,而水合物的功能可以参与凝聚反应.此外,2-mingobenzohydazide可能展示生物活动,从而导致研究其作为抗微生物剂或抗癌剂的潜力.应当参考安全数据,以便处理和储存,如同任何化学物质一样,确保采取适当的预防措施.

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上下游产品

CAS号87-25-2 2-氨基苯甲酸乙酯 | CAS号118-48-9 靛红酸酐 | CAS号134-20-3 邻氨基苯甲酸甲酯 | CAS号118-92-3 邻氨基苯甲酸 | CAS号31385-12-3 methyl 2-[(trif... | CAS号16417-02-0 3-丁基-4(3h)-喹唑啉酮 | CAS号21563-73-5 Benzoyl chlorid... | CAS号79903-04-1 N-butyl-2-nitro... | CAS号10494-82-3 2-氨基-N-丁基苯甲酰胺( | CAS号610-14-0 2-硝基苯甲酰氯 | CAS号14663-46-8 3-氨基-4(3H)-喹唑啉酮 | CAS号57711-25-8 3,4-dihydro-1,3... | CAS号14663-48-0 ethyl (1E)-N-(4... | CAS号90-16-4 3,4-二氢-4-氧-1,2,... | CAS号19542-04-2 2-[5-(2-aminoph... | CAS号19050-68-1 2-amino-N-[(4-m... | CAS号30386-01-7 3-氨基-1H-喹唑烷-2,4-二酮 | CAS号28864-26-8 Benzoic acid, 2... | CAS号25518-15-4 2-(3-Phenyl-1H-...

合成工艺路线路线简述

    📜2-氨基苯甲酸乙酯置于一水合肼体系中,用 乙醇 用作溶剂,化学反应生成2-氨基亚苯基肼
    参考文献:铬(III)-肼化物配合物的化学,光谱学和抗氧化活性研究
    标题:铬(III)-肼化物配合物的化学,光谱学和抗氧化活性研究
    摘要:酰肼由于其生物活性而成为重要的化学实体.与某些金属离子络合后,已知它们的生物学活性会得到正向增强.本工作介绍了cr(III)-酰肼配合物的合成及其结构,光谱和抗氧化性能,以揭示其化学和生物化学性质. 物理(磁矩,电导率测量),分析(c,H,N和cr分析)和光谱(ei-Mass,Ftir)技术用于表征合成化合物.所有cr(III)-酰肼络合物均具有八面体几何结构,通式为[cr(l)2(h 2 O)2 ] Cl 3.在这些配合物中,酰肼配体通过羰基氧和末端氨基氮以二齿形式配位. 筛选了所有cr(III)-酰肼配合物的体外二苯基二吡啶甲基肼(dpph),超氧化物歧化酶和一氧化氮自由基清除活性.发现大多数cr(III)-酰肼配合物比其未配位的酰肼配体更有效.这项研究证明了一个有趣的结构-活性关系(sar),在此介绍.
    Doi:10.2174/1573406411666150401103442

    海关参考信息

    专利信息


    专利号:US-4713383-A
    优先权日:1984-10-01
    标 题:Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
    发明人:FRANCIS JOHN E; GELOTTE KARL O
    权利人:CIBA GEIGY CORP
    摘要:[1,2,4]triazolo[1,5-c]quinazoline compounds of the formula wherein R1 is optionally substituted phenyl, pyridyl, furyl thienyl, dihydro or tetrahydro furanyl or thienyl, pyranyl, or 0-ribofuranosyl; R2 is hydrogen or lower alkyl; X is oxygen or NR3, R3 is as defined in the claims, and ring A is unsubstituted or substituted as set forth in the claims. The compounds wherein X is N-R3 are especially useful as adenosine antagonists and for the treatment of asthma. The compounds wherein X is oxygen are useful as benzodiazepine antagonists and as intermediates in the synthesis of the compounds wherein X is N-R3.

    专利号:US-6429311-B2
    优先权日:1997-12-15
    标 题:Compositions containing N-amino- and N-hydroxy-quinazolinones and methods for preparing libraries thereof
    发明人:GAO YUN
    权利人:SEPRACOR INC
    摘要:The present invention is directed to certain N-amino- and N-hydroxy-quinazolinone compounds and synthetic methods for synthesis thereof, which compounds may find use in combinatorial libraries. More specifically, the invention is directed to the synthesis of 3-hydroxy- and 3-amino-4 (1H)-quinazolinones via the reaction of an appropriate 2-aminobenzamide compound with a carboxylic acid or acyl halide at ambient temperature performed on a solid support or in solution.

    专利号:US-9943809-B2
    优先权日:2014-02-27
    标题 :Solvent resistant thin film composite membrane and its preparation
    发明人:DOM ELKE; HERMANS SANNE; KOECKELBERGHS GUY; VANKELECOM IVO
    权利人:KATHOLIEKE UNIV LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT; UNIV LEUVEN KATH
    摘要:The present invention relates to improved methods for synthesis of thin film composite membranes by interfacial polymerization. More in particular, the method of the present invention comprises the impregnation of an ultrafiltration porous support membrane with an aqueous solution containing a polyfunctional nucleophilic monomer, and contacting the impregnated support membrane with a second largely water-immiscible solvent containing a polyfunctional epoxide monomer.

    专利号:CN-107698599-A
    优先权日:2017-09-26
    标题:Synthesis of pyridazino[6,1‑b]pyrrolo[1,2‑a]quinazolinone derivatives

    专利号:CN-115785133-A
    优先权日:2022-12-02
    标题:In-situ synthesis method and application of quinazolinone Schiff base dysprosium complex

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Synthesis And Properties Of 1,2-Dihydro-4(3H)-Quinazolinones
    作者:D. S. Khachatryan,S. K. Belus,V. A. Misyurin,M. A. Baryshnikova,A. V. Kolotaev,K. R. Matevosyan |发布日期:2017.6
    摘要:We Modified The Preparative-Scale Method For The Synthesis Of 2-Aryl 1,2-Dihydro-4(3H)-Quinazolinone Derivatives Obtained In High Yields By The Reaction Of New And Commercially Available Aromatic Aldehydes With Anthranilic Acid Amides. A Series Of Quinazolinone Derivatives Possessing Anticancer And Antiparasitic Activities, As Well As Capable Of Preventing The Progress Of Neurodegenerative Diseases

    合成参考文献


    参考文献:10.1007/bf02152135
    摘要:Casy AF. Ketal formation in 4-piperidones. Cellular and Molecular Life Sciences. 1964 Aug;20(8):437–8. doi: 10.1007/bf02152135.
    摘要:V. D. Canic. Naturwiss. 46, 575 (1959).
    摘要:Collier, S. J., Science of Synthesis, (2004) 13, 367.
    摘要:Weaver, G. W., Science of Synthesis, (2004) 13, 222.
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