CAS: 1878-91-7; 4-Bromophenoxyacetic Acid

上下游产品

CAS号6964-29-0 (4-溴苯氧基)乙酸乙酯 | CAS号106-41-2 对溴苯酚 | CAS号79-11-8 氯乙酸 | CAS号122-59-8 苯氧乙酸 | CAS号4841-23-0 (4-bromophenoxy... | CAS号79-08-3 溴乙酸 | CAS号2555-49-9 苯氧乙酸乙酯 | CAS号7726-95-6 溴素 | CAS号7553-56-2 碘 | CAS号64-19-7 冰醋酸 | CAS号106-41-2 对溴苯酚 | CAS号122-59-8 苯氧乙酸 | CAS号124-38-9 二氧化碳 | CAS号201230-82-2 carbon monoxide | CAS号50-00-0 甲醛 | CAS号6964-29-0 (4-溴苯氧基)乙酸乙酯 | CAS号35368-75-3 2-(4-溴苯氧基)乙酰胺 | CAS号16738-06-0 (4-Bromophenoxy... | CAS号16738-00-4 (4-溴苯氧基)-乙酸肼

(4-溴苯氧基)乙酸甲酯置于氢氧化钾体系中,用 甲醇 用作溶剂,化学反应 1.0H,以87%的收率获得对溴苯氧乙酸
参考文献:常温下用koh-甲醇轻松水解酯
标题:常温下用koh-甲醇轻松水解酯
摘要:据报道,一种简单,快速,有效的方法是在环境温度(约35oc)下用氢氧化钾在甲醇中水解各种芳香族,脂肪族,脂肪族和杂环酸的单酯和二酯.
Doi:10.1007/s00706-003-0114-1

专利信息

专利号:US-7915201-B2
优先权日:2003-03-20
标 题:Ligational encoding of small molecules
发明人：FRANCH THOMAS; JACOBSEN SOEREN NYBOE; RASMUSSEN TORBEN RAVN; NEVE SOEREN; PEDERSEN HENRIK; GOULIAEV ALEX HAAHR
权利人:NUEVOLUTION AS
摘要:The invention relates to a method for synthesising a bifunctional complex comprising an encoded molecule and an identifier polynucleotide identifying the chemical entities having participated in the synthesis of the encoded molecule, said method comprising the steps of i) providing a) at least one template comprising one or more codons capable of hybridising to an anti-codon, wherein said template is optionally associated with one or more chemical entities, and b) a plurality of building blocks each comprising an anti-codon associated with one or more chemical entities, and ii) hybridising the anti-codon of one or more of the provided building blocks to the template, iii) covalently linking said anti-codons and/or linking the at least one template with the anti-codon of at least one building block, thereby generating an identifier polynucleotide capable of identifying chemical entities having participated in the synthesis of the encoded molecule, iv) separating the template from one or more of the anti-codons hybridised thereto, thereby generating an at least partly single stranded identifier polynucleotide associated with a plurality of chemical entities, v) generating a bifunctional complex comprising an encoded molecule and an identifier polynucleotide identifying the chemical entities having participated in the synthesis of the encoded molecule, wherein said encoded molecule is generated by reacting at least two of said plurality of chemical entities associated with the identifier polynucleotide, and wherein said at least two chemical entities are provided by separate building blocks.

专利号:US-2024400608-A1
优先权日:2021-09-03
标题:Synthesis of bicycle toxin conjugates, and intermediates thereof
发明人：WITTY DAVID; LIMB DARREN; MIN BYOUNG JOON; HE LIWEN; SANDERS WILLIAM J; NNANABU ERNEST OBINNA
权利人:BRICYCLETX LTD
摘要:The present invention relates to Bicycle toxin conjugates, methods for preparation, and methods of use for treating cancer.

专利号:WO-2023137518-A1
优先权日:2022-01-21
标题 :Platinum complexes
发明人：ALDRICH-WRIGHT JANICE; GORDON CHRISTOPHER; DEO KRISHANT M; KHOURY ALEEN; MCGHIE BRONDWYN; APUTEN ANGELICO; PLATTEN-MENTI MARIA; RASHID FATIN; JURISINEC ASHLEY; SOLIMAN SARAH
权利人:WESTERN SYDNEY UNIV
摘要:The present disclosure relates to platinum complexes, and in particular platinum(II) and platinum(IV) complexes. The present disclosure also relates to synthesis of the platinum complexes, and to intermediates for the synthesis of the platinum complexes. The present disclosure also relates to methods and use of the platinum complexes for treating cancer.

专利号:WO-2023031623-A2
优先权日:2021-09-03
标 题 :Synthesis of bicycle toxin conjugates, and intermediates thereof

专利号:CN-118103075-A
优先权日:2021-09-03
标题 :Synthesis of bicyclic peptide toxin conjugates and intermediates thereof

专利号:EP-4395830-A2
优先权日:2021-09-03
标 题 :Synthesis of bicycle toxin conjugates, and intermediates thereof