CAS: 1203-68-5; [1,1'-Biphenyl]-2-Carbaldehyde

相似化合物

24973-49-7 2928-43-0 947-84-2

上下游产品

N-(2-phenylbenzoyl)-N'-benzensulfonylhydrazine iodobenzene ortho-bromobenzaldehyde biphenyl-2-ylmagnesium iodide 2-biphenylmethanol (Z)-2-(2-phenylbenzylidene)-3-quinuclidinone α-(cumen-3'-yl)biphenyl-2-methanol α-(4'-chlorophenyl)biphenyl-2-methanol

📜二氢-3-(异十二碳烯基)呋喃-2,5-二酮置于manganese(Iv) Oxide,Lithium Aluminium Tetrahydride体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 4.0H,反应生成联苯-2-甲醛
参考文献:通过ru(II)催化的[3 + 2]环空和分子内friedel-Crafts环化一锅法合成多取代的螺芴-茚
标题:通过ru(II)催化的[3 + 2]环空和分子内friedel-Crafts环化一锅法合成多取代的螺芴-茚
摘要:Ru(II)通过[3 + 2]环化催化一锅法合成多取代的螺芴-茚,然后实现了分子内friedel-Crafts烷基化.这种简单的方法提供了广泛的芳基酮和内部炔烃,以中等到非常好的收率获得了pahs骨架.
Doi:10.1021/acs.Joc.5B01517

专利信息

专利号:US-2016200665-A1
优先权日:2013-08-21
标 题:Synthesis of biphenylalaninol via novel intermediates
发明人：ZIMMERMANN AXEL; HERMSEN PETRUS JOHANNES; HANBAUER MARTIN HELMUT FRIEDRICH
权利人:DPX HOLDINGS BV
摘要:The invention relates to a novel synthesis route towards R-biphenylalaninol and to the intermediates applied in this synthesis route. The process according to the invention and the intermediate compounds are useful in the synthesis of pharmaceutically active compounds.

专利号:US-9139515-B2
优先权日:2011-08-19
标 题:Synthesis of R-biphenylalaninol
发明人：HERMSEN PETRUS JOHANNES; ERMANN PETER HANS; RIEBEL PETER HANS; WOLBERG MICHAEL; DE VRIES ANDREAS HENDRIKUS MARIA
权利人:HERMSEN PETRUS JOHANNES; ERMANN PETER HANS; RIEBEL PETER HANS; WOLBERG MICHAEL; DE VRIES ANDREAS HENDRIKUS MARIA; DPX HOLDINGS BV
摘要:This invention relates to a novel process for the synthesis of R-biphenylalaninol and to intermediate compounds that are formed in the process according to the invention, i.e. novel intermediates useful in the synthesis of R-biphenylalaninol. The invention also relates to R-biphenylalaninol, The process according to the invention, the intermediates to of R-biphenylalaninol and of R-biphenylalaninol are all useful in the synthesis of pharmaceutically active compounds.

专利号:WO-2004011474-A1
优先权日:2002-07-31
标题:Universal support media for synthesis of oligomeric compounds
发明人：GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
权利人:ISIS PHARMACEUTICALS INC; GUZAEV ANDREI P; MANOHARAN MUTHIAH; RAVIKUMAR VASULINGA T; KUMAR RAJU K
摘要:Compounds for the synthesis of oligomeric compounds, particularly oligonucleotide and oligonucleotide mimetics, are provided. In addition, methods for functionalizing a support medium with a first monomeric subunit and methods for the synthesis of oligomeric compounds utilizing the novel compounds bound to support media are provided.

专利号:US-4140708-A
优先权日:1975-10-16
标 题 :Asymmetric synthesis of optically active prostaglandins
发明人：CHADHA NARESH K; PARTRIDGE JR JOHN J; USKOKOVIC MILAN R
权利人:HOFFMANN LA ROCHE
摘要:An asymmetric synthesis of optically active prostaglandin F 2 α from cyclopentadiene including intermediates in this synthesis.

专利号:US-3933892-A
优先权日:1973-02-12
标题 :Asymmetric synthesis of optically active prostaglandins
发明人：CHADHA NARESH KUMAR; PARTRIDGE JR JOHN JOSEPH; USKOKOVIC MILAN RADOJE
权利人:HOFFMANN LA ROCHE
摘要:An asymmetric synthesis of optically active prostaglandin F 2 .sub.α from cyclopentadiene including intermediates in this synthesis.

专利号:US-10323010-B2
优先权日:2015-07-20
标题 :Methods of chemical synthesis of substituted 10H-phenothiazine-3,7-diamine compounds
发明人：STOREY JOHN MERVYN DAVID; LARCH CHRISTOPHER PAUL; KEMP STEVEN JOHN; CLUNAS SCOTT; NICOLL SARAH LOUISE; GIBBARD HELEN SARAH; SIMPSON MICHAEL; SINCLAIR JAMES PETER; MARSHALL COLIN
权利人:WISTA LAB LTD
摘要:The present invention pertains generally to the field of chemical synthesis, and more particularly to methods of chemical synthesis which include the step of preparing a substituted 10H-phenothiazine-3,7-diamine compound of Formula (1) by a step of selective alkylation by reductive amination, in which the corresponding unsubstituted diamine of Formula (4) is reacted with aldehyde/ketone, under reductive amination conditions. The present invention also relates to such methods which incorporate additional subsequent and/or preceding steps, for example, to prepare compounds of Formulae (2) and (3) from compounds of Formula (1), and to prepare compounds of Formula (4) from, for example, compounds of Formulae (5), (6), (7), (8), and (9). Compounds of Formula (1), Formula (2), and Formula (3) are useful, for example, in the treatment of diseases of protein aggregation, such as Alzheimer's disease.