CAS: 102089-75-8; (R)-2-((Tert-Butoxycarbonyl)Amino)-2-Phenylethyl Methanesulfonate

相似化合物

67341-01-9 117049-14-6 102089-74-7

上下游产品

Boc-D-苯甘氨醇 (R)-N-(Tert-Butoxycarbonyl)Phenylglycinol 102089-74-7
Tert-Butyl 2-Hydroxy-1-Phenylethylcarbamate
(R)-N-(Tert-Butoxycarbonyl)Phenylglycine Methyl Ester

(R)-N-(Tert-Butoxycarbonyl)Phenylglycine Methyl Ester置于锂硼氢,三乙胺体系中,用 乙醇,二氯甲烷 用作溶剂,化学反应 0.5H,反应生成N-[(1R)-2-[(甲基磺酰基)氧基]-1-苯基乙基]氨基甲酸叔丁酯
参考文献:Higashiura,Kunihiko; Morino,Hiroe; Matsuura,Hirohide,Journal Of The Chemical Society. Perkin Transactions I,1989,P. 1479-1481
标题:Higashiura,Kunihiko; Morino,Hiroe; Matsuura,Hirohide,Journal Of The Chemical Society. Perkin Transactions I,1989,P. 1479-1481

专利信息

专利号:US-11858901-B2
优先权日:2019-10-30
标 题:3-((R)-2-(amino-2-phenylethyl)-1-(2-fluoro-6 trifluoromethyl benzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione or a salt thereof, process for its preparation, and its use in the synthesis of elagolix
发明人：BALLETTE ROBERTO; JIMÉNEZ ALONSO OSCAR; GARCÃ?A GARCÃ?A ELENA; DOBARRO RODRÃ?GUEZ ALICIA
权利人:MOEHS IBERICA SL
摘要:A new intermediate is useful in the synthesis of elagolix. A process for obtaining the intermediate includes reacting a precursor with iodine monochloride in the presence of an organic solvent. A process for preparing elagolix makes use of the intermediate. The intermediate can be 3-((R)-2-(amino-2-phenylethyl)-1-(2-fluoro-6-trifluoromethylbenzyl)-5-iodo-6-methyl-1H-pyrimidine-2,4-dione or a salt thereof, such as a hydrochloride.

专利号:US-2018312463-A1
优先权日:2015-10-22
标题:Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products
发明人：YELM KENNETH EDWARD; WOS JOHN AUGUST; BUNKE GREGORY MARK; FREDERICK HEATH; HAUGHT JOHN CHRISTIAN; HOKE STEVEN HAMILTON; SREEKRISHNA KOTI TATACHAR; LIN YAKANG
权利人:PROCTER & GAMBLE
摘要:Synthesis methods to produce a series of carboxamides built off of an (S)-2-amino acid backbone or an (R)-2-amino acid backbone, depending upon the desired diastereomer of the end product.

专利号:WO-2017070418-A1
优先权日:2015-10-22
标 题:Synthesis of cyclohexane carboxamide derivatives useful as sensates in consumer products

专利号:US-2022411382-A1
优先权日:2019-10-30
标 题 :3-((r)-2-(amino-2-phenylethyl)-1-(2-fluoro-6 trifluoromethyl benzyl)-5-iodo-6-methyl-1h-pyrimidine-2,4-dione or a salt thereof, process for its preparation, and its use in the synthesis of elagolix

专利号:EP-3365324-A1
优先权日:2015-10-22
标题:Synthesis of cyclohexane carboxamide derivatives useful as sensates in consumer products

专利号:ES-2822398-B2
优先权日:2019-10-30
标 题:3-((R)-2-(Amino-2-phenylethyl)-1-(2-fluoro-6-trifluoromethylbenzyl)-5-iodo-6-methyl-1H-pyrimidin-2,4-dione or a salt of the same, procedure for its preparation and its use in the synthesis of elagolix